메뉴 건너뛰기




Volumn 134, Issue 4, 2014, Pages 909-913

Ex vivo reversal of the anticoagulant effects of edoxaban

Author keywords

Anticoagulant reversal; Edoxaban; EIBA; Factor Xa; rFVIIa

Indexed keywords

ACTIVATED PROTHROMBIN COMPLEX; BIOLOGICAL MARKER; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 10A ANTIBODY; D DIMER; EDOXABAN; PROTEIN ANTIBODY; RECOMBINANT BLOOD CLOTTING FACTOR 7A; UNCLASSIFIED DRUG; ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR; BLOOD CLOTTING FACTOR 7A; HEMOSTATIC AGENT; PYRIDINE DERIVATIVE; RECOMBINANT FVIIA; RECOMBINANT PROTEIN; THIAZOLE DERIVATIVE;

EID: 84908145070     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2014.07.036     Document Type: Article
Times cited : (41)

References (25)
  • 1
  • 3
    • 84885618705 scopus 로고    scopus 로고
    • Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism
    • The Hokusai-VTE Investigators. Buller HR, Decousus H, Grosso MA, Mercuri M, Middeldorp S, et al. Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism. N Engl J Med 2013;369:1406-15.
    • (2013) N Engl J Med , vol.369 , pp. 1406-1415
    • Buller, H.R.1    Decousus, H.2    Grosso, M.A.3    Mercuri, M.4    Middeldorp, S.5
  • 4
    • 77953787643 scopus 로고    scopus 로고
    • Clinical safety, tolerability, pharmacokinetics, and pharmacodynamics of the novel factor Xa inhibitor edoxaban in healthy volunteers
    • Ogata K, Mendell-Harary J, Tachibana M, Masumoto H, Oguma T, Kojima M, et al. Clinical safety, tolerability, pharmacokinetics, and pharmacodynamics of the novel factor Xa inhibitor edoxaban in healthy volunteers. J Clin Pharmacol 2010;50:743-53.
    • (2010) J Clin Pharmacol , vol.50 , pp. 743-753
    • Ogata, K.1    Mendell-Harary, J.2    Tachibana, M.3    Masumoto, H.4    Oguma, T.5    Kojima, M.6
  • 5
    • 84885129987 scopus 로고    scopus 로고
    • Drug-drug interaction studies of cardiovascular drugs involving P-glycoprotein, an efflux transporter, on the pharmacokinetics of edoxaban, an oral factor Xa inhibitor
    • Mendell J, Zahir H, Matsushima N, Noveck R, Lee F, Chen S, et al. Drug-drug interaction studies of cardiovascular drugs involving P-glycoprotein, an efflux transporter, on the pharmacokinetics of edoxaban, an oral factor Xa inhibitor. Am J Cardiovasc Drugs 2013;13:331-42.
    • (2013) Am J Cardiovasc Drugs , vol.13 , pp. 331-342
    • Mendell, J.1    Zahir, H.2    Matsushima, N.3    Noveck, R.4    Lee, F.5    Chen, S.6
  • 6
    • 84877743192 scopus 로고    scopus 로고
    • Treatment of bleeding complications when using oral anticoagulants for prevention of strokes
    • Akwaa F, Spyropoulos AC. Treatment of bleeding complications when using oral anticoagulants for prevention of strokes. Curr Treat Options Cardio Med 2013;15:288-98.
    • (2013) Curr Treat Options Cardio Med , vol.15 , pp. 288-298
    • Akwaa, F.1    Spyropoulos, A.C.2
  • 7
    • 84880737167 scopus 로고    scopus 로고
    • Practical management of bleeding due to the anticoagulants dabigatran, rivaroxaban, and apixaban
    • Fawole A, Daw HA, Crowther MA. Practical management of bleeding due to the anticoagulants dabigatran, rivaroxaban, and apixaban. Cleve Clin J Med 2013;80:443-51.
    • (2013) Cleve Clin J Med , vol.80 , pp. 443-451
    • Fawole, A.1    Daw, H.A.2    Crowther, M.A.3
  • 8
    • 84898538852 scopus 로고    scopus 로고
    • Novel oral anticoagulants: Pharmacology, coagulation measures, and considerations for reversal
    • Jackson II LR, Becker RC. Novel oral anticoagulants: pharmacology, coagulation measures, and considerations for reversal. J Thromb Thrombolysis 2014;37:380-91.
    • (2014) J Thromb Thrombolysis , vol.37 , pp. 380-391
    • Jackson, L.R.1    Becker, R.C.2
  • 9
    • 80052635170 scopus 로고    scopus 로고
    • New anticoagulants: How to deal with treatment failure and bleeding complications
    • Kazmi RS, Lwaleed BA. New anticoagulants: how to deal with treatment failure and bleeding complications. Br J Clin Pharmacol 2011;72:593-603.
    • (2011) Br J Clin Pharmacol , vol.72 , pp. 593-603
    • Kazmi, R.S.1    Lwaleed, B.A.2
  • 10
    • 84878645045 scopus 로고    scopus 로고
    • Managing new oral anticoagulants in the perioperative and intensive care unit setting
    • Levy JH, Faraoni D, Spring JL, Douketis JD, Samama CM. Managing new oral anticoagulants in the perioperative and intensive care unit setting. Anesthesiology 2013;118:1466-74.
    • (2013) Anesthesiology , vol.118 , pp. 1466-1474
    • Levy, J.H.1    Faraoni, D.2    Spring, J.L.3    Douketis, J.D.4    Samama, C.M.5
  • 12
    • 84880571372 scopus 로고    scopus 로고
    • Management of major bleeding complications and emergency surgery in patients on long-term treatment with direct oral anticoagulants, thrombin or factor-Xa inhibitors: Proposals of the working group on perioperative haemostasis (GIHP) - March 2013
    • Pernod G, Albaladejo P, Godier A, Samama CM, Susen S, Gruel Y, et al. Management of major bleeding complications and emergency surgery in patients on long-term treatment with direct oral anticoagulants, thrombin or factor-Xa inhibitors: proposals of the working group on perioperative haemostasis (GIHP) - March 2013. Arch Cardiovasc Dis 2013;106:382-93.
    • (2013) Arch Cardiovasc Dis , vol.106 , pp. 382-393
    • Pernod, G.1    Albaladejo, P.2    Godier, A.3    Samama, C.M.4    Susen, S.5    Gruel, Y.6
  • 13
    • 82955195818 scopus 로고    scopus 로고
    • Surgery and invasive procedures in patients on long-term treatment with direct oral anticoagulants: Thrombin or factor-Xa inhibitors. Recommendations of the Working Group on Perioperative Haemostasis and the French Study Group on Thrombosis and Haemostasis
    • Sie P, Samama CM, Godier A, Rosencher N, Steib A, Llau JV, et al. Surgery and invasive procedures in patients on long-term treatment with direct oral anticoagulants: thrombin or factor-Xa inhibitors. Recommendations of the Working Group on Perioperative Haemostasis and the French Study Group on Thrombosis and Haemostasis. Arch Cardiovasc Dis 2011;104:669-76.
    • (2011) Arch Cardiovasc Dis , vol.104 , pp. 669-676
    • Sie, P.1    Samama, C.M.2    Godier, A.3    Rosencher, N.4    Steib, A.5    Llau, J.V.6
  • 14
    • 84878479730 scopus 로고    scopus 로고
    • Full prescribing information. Bagsvaerd, Denmark: Novo Nordisk A/S; Available at
    • NovoSeven® RT Coagulation Factor VIIa (Recombinant). Full prescribing information. Bagsvaerd, Denmark: Novo Nordisk A/S; 2012 [Available at: http://www.novo-pi.com/novosevenrt.pdf].
    • (2012) NovoSeven® RT Coagulation Factor VIIa (Recombinant)
  • 15
    • 59049098711 scopus 로고    scopus 로고
    • Evaluation of the safety and pharmacokinetics of a fast-acting recombinant FVIIa analogue, NN1731, in healthy male subjects
    • Moss J, Scharling B, Ezban M, Moller Sorensen T. Evaluation of the safety and pharmacokinetics of a fast-acting recombinant FVIIa analogue, NN1731, in healthy male subjects. J Thromb Haemost 2009;7:299-305.
    • (2009) J Thromb Haemost , vol.7 , pp. 299-305
    • Moss, J.1    Scharling, B.2    Ezban, M.3    Moller Sorensen, T.4
  • 17
    • 35148857177 scopus 로고    scopus 로고
    • Factor eight inhibitor bypass activity (FEIBA) in the management of bleeds in hemophilia patientswith high-titer inhibitors
    • Tjonnfjord GE, Holme PA. Factor eight inhibitor bypass activity (FEIBA) in the management of bleeds in hemophilia patientswith high-titer inhibitors. Vasc Health Risk Manag 2007;3:527-31.
    • (2007) Vasc Health Risk Manag , vol.3 , pp. 527-531
    • Tjonnfjord, G.E.1    Holme, P.A.2
  • 18
    • 85028290261 scopus 로고    scopus 로고
    • Full prescribing information. Marburg, Germany: CSL Behring GmbH; Available at
    • Prothrombin Complex Concentrate (Human), Kcentra™. Full prescribing information. Marburg, Germany: CSL Behring GmbH; 2013 [Available at: www.kcentra.com/prescribing-information.aspx].
    • (2013) Prothrombin Complex Concentrate (Human), Kcentra™
  • 19
    • 84856631805 scopus 로고    scopus 로고
    • Reversal of anticoagulant effects of edoxaban, an oral, direct factor Xa inhibitor, with haemostatic agents
    • Fukuda T, Honda Y, Kamisato C, Morishima Y, Shibano T. Reversal of anticoagulant effects of edoxaban, an oral, direct factor Xa inhibitor, with haemostatic agents. Thromb Haemost 2012;107:253-9.
    • (2012) Thromb Haemost , vol.107 , pp. 253-259
    • Fukuda, T.1    Honda, Y.2    Kamisato, C.3    Morishima, Y.4    Shibano, T.5
  • 20
    • 84896117299 scopus 로고    scopus 로고
    • Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: A meta-analysis of randomised trials
    • Ruff CT, Giugliano RP, Braunwald E, Hoffman EB, Deenadayalu N, Ezekowitz MD, et al. Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials. Lancet 2014;383:955-62. http://dx.doi.org/10.1016/S0140-6736(13)62343-0.
    • (2014) Lancet , vol.383 , pp. 955-962
    • Ruff, C.T.1    Giugliano, R.P.2    Braunwald, E.3    Hoffman, E.B.4    Deenadayalu, N.5    Ezekowitz, M.D.6
  • 21
    • 84864370719 scopus 로고    scopus 로고
    • Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: A randomised crossover ex vivo study in healthy volunteers
    • Marlu R, Hodaj E, Paris A, Albaladejo P, Crackowski JL, Pernod G. Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: A randomised crossover ex vivo study in healthy volunteers. Thromb Haemost 2012;108:217-24.
    • (2012) Thromb Haemost , vol.108 , pp. 217-224
    • Marlu, R.1    Hodaj, E.2    Paris, A.3    Albaladejo, P.4    Crackowski, J.L.5    Pernod, G.6
  • 22
    • 84907362631 scopus 로고    scopus 로고
    • Current strategies to minimize the bleeding risk of warfarin
    • Snipelisky D, Kusumoto F. Current strategies to minimize the bleeding risk of warfarin. J Blood Med 2013;4:89-99.
    • (2013) J Blood Med , vol.4 , pp. 89-99
    • Snipelisky, D.1    Kusumoto, F.2
  • 23
    • 84655176578 scopus 로고    scopus 로고
    • Evaluation of prothrombin complex concentrate and recombinant activated factor VII to reverse rivaroxaban in a rabbit model
    • Godier A, Miclot A, Le Bonniec B, Durand M, Fischer AM, Emmerich J, et al. Evaluation of prothrombin complex concentrate and recombinant activated factor VII to reverse rivaroxaban in a rabbit model. Anesthesiology 2012;116:94-102.
    • (2012) Anesthesiology , vol.116 , pp. 94-102
    • Godier, A.1    Miclot, A.2    Le Bonniec, B.3    Durand, M.4    Fischer, A.M.5    Emmerich, J.6
  • 24
    • 84886258579 scopus 로고    scopus 로고
    • Evaluation of recombinant activated factor VII, prothrombin complex concentrate, and fibrinogen concentrate to reverse apixaban in a rabbit model of bleeding and thrombosis
    • Martin AC, Le Bonniec B, Fischer AM, Marchand-Leroux C, Gaussem P, Samama CM, et al. Evaluation of recombinant activated factor VII, prothrombin complex concentrate, and fibrinogen concentrate to reverse apixaban in a rabbit model of bleeding and thrombosis. Int J Cardiol 2013;168:4228-33.
    • (2013) Int J Cardiol , vol.168 , pp. 4228-4233
    • Martin, A.C.1    Le Bonniec, B.2    Fischer, A.M.3    Marchand-Leroux, C.4    Gaussem, P.5    Samama, C.M.6
  • 25
    • 84906939260 scopus 로고    scopus 로고
    • Four-factor prothrombin complex concentrate (4-PCC) effectively reverses edoxaban induced bleeding in a rabbit model of acute injury
    • Herzog E, Kaspereit F, Krege W, Pragst I, Yoshiyuki M, Dickneite G. Four-factor prothrombin complex concentrate (4-PCC) effectively reverses edoxaban induced bleeding in a rabbit model of acute injury. Blood 2013;122:1133.
    • (2013) Blood , vol.122 , pp. 1133
    • Herzog, E.1    Kaspereit, F.2    Krege, W.3    Pragst, I.4    Yoshiyuki, M.5    Dickneite, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.