Localized micro- and nano-scale remodelling in the diabetic aorta

Acta Biomaterialia

Volumn 10, Issue 11, 2014, Pages 4843-4851

  Akhtar, R ^a   Cruickshank, J K ^b   Zhao, X ^c   Walton, L A ^d   Gardiner, N J ^e   Barrett, S D ^a   Graham, H K ^e   Derby, B ^c   Sherratt, M J ^e  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Arterial stiffening; Extracellular matrix; Fibrillin microfibrils; Mechanical properties; Type 1 diabetes

Indexed keywords

ATOMIC FORCE MICROSCOPY; BIOMECHANICS; MACROMOLECULES; NANOTECHNOLOGY; RATS; SCAFFOLDS (BIOLOGY); SIZE EXCLUSION CHROMATOGRAPHY; STIFFNESS; TISSUE;

ARTERIAL STIFFENING; EXTRACELLULAR MATRICES; EXTRACELLULAR PROTEASE; FIBRILLIN; FIBRILLIN MICROFIBRIL; LOCALISED; MICROFIBRIL; PROTEASE ACTIVITIES; TISSUE REMODELING; TYPE 1 DIABETES;

BLOOD VESSELS;

ELASTIN; FIBRILLAR COLLAGEN; FIBRILLIN; FIBRILLIN MICROFBRIL; GELATIN; PROTEINASE; STREPTOZOCIN; STRUCTURAL PROTEIN; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; COLLAGEN; GELATINASE; GLUCOSE BLOOD LEVEL;

ACOUSTIC MICROSCOPY; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTERIAL STIFFNESS; ARTICLE; ATOMIC FORCE MICROSCOPY; BLOOD VESSEL REMODELLING; BLOOD VESSEL WALL; CONTROLLED STUDY; DISEASE MODEL; ELASTIC FIBER; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; GEL PERMEATION CHROMATOGRAPHY; GLYCATION; IN VITRO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; MALE; NONHUMAN; PROTEIN DEGRADATION; RAT; RAT MODEL; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; ULTRASTRUCTURE; VASCULAR DISEASE; ZYMOGRAPHY; ANIMAL; BLOOD; BODY WEIGHT; DIABETES MELLITUS; FIBER; GLUCOSE BLOOD LEVEL; GLYCOSYLATION; METABOLISM; NANOTECHNOLOGY; PATHOLOGY; PATHOPHYSIOLOGY; SOUND; TUNICA MEDIA; VASCULAR REMODELING; WISTAR RAT;

ANIMALS; AORTA; BLOOD GLUCOSE; BODY WEIGHT; COLLAGEN; DIABETES MELLITUS; GELATINASES; GLYCOSYLATION; MALE; MICROFIBRILS; MICROFILAMENT PROTEINS; NANOTECHNOLOGY; RATS, WISTAR; SOUND; TUNICA MEDIA; VASCULAR REMODELING;

EID: 84908121980     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2014.07.001     Document Type: Article

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