Let-7b/g silencing activates AKT signaling to promote gastric carcinogenesis

Journal of Translational Medicine

Volumn 12, Issue 1, 2014, Pages

  Kang, Wei ^a,b,c   Tong, Joanna H M ^a,b   Lung, Raymond W M ^a,b   Dong, Yujuan ^b   Yang, Weiqin ^b   Pan, Yi ^a,b   Lau, Kin M ^a   Yu, Jun ^b   Cheng, Alfred S L ^b   To, Ka F ^a,b,c  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c THE CHINESE UNIVERSITY OF HONG KONG   (China)

Author keywords

AKT2; Gastric cancer; let 7b; let 7g; Tumor suppressor

Indexed keywords

MICRORNA; PROTEIN KINASE B; SMALL INTERFERING RNA; 3' UNTRANSLATED REGION; AKT2 PROTEIN, HUMAN; MIRNLET7 MICRORNA, HUMAN; PROTEIN BINDING;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CANCER SURVIVAL; CARCINOGENESIS; CELL INVASION ASSAY; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; DOWN REGULATION; DOWNSTREAM PROCESSING; ENZYME ACTIVATION; ENZYME BINDING; GASTRIC CANCER CELL LINE; GENE EXPRESSION; GENE FUNCTION; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; LET 7B GENE; LET 7G GENE; LYMPH NODE METASTASIS; MALE; MOUSE; MTT ASSAY; NONHUMAN; ONCOGENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STOMACH CANCER; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; NUDE MOUSE; PATHOLOGY; STOMACH TUMOR; SURVIVAL; TUMOR CELL LINE; UPREGULATION;

3' UNTRANSLATED REGIONS; ANIMALS; BASE SEQUENCE; CARCINOGENESIS; CELL LINE, TUMOR; CELL PROLIFERATION; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; HUMANS; MICE, NUDE; MICRORNAS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; SURVIVAL ANALYSIS; UP-REGULATION;

EID: 84908087069     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/s12967-014-0281-3     Document Type: Article

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