Heterodimerization of apelin receptor and neurotensin receptor 1 induces phosphorylation of ERK1/2 and cell proliferation via Gαq-mediated mechanism

Journal of Cellular and Molecular Medicine

Volumn 18, Issue 10, 2014, Pages 2071-2081

  Bai, Bo ^a   Cai, Xin ^a   Jiang, Yunlu ^a   Karteris, Emmanouil ^b   Chen, Jing ^a,c  

^a JINING MEDICAL UNIVERSITY   (China)

^b BRUNEL UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

Apelin receptor; ERK 1 2; G protein coupled receptor; Heterodimerization; Neurotensin receptor 1; Resonance energy transfer

Indexed keywords

APLNR PROTEIN, HUMAN; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; MAPK1 PROTEIN, HUMAN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEUROTENSIN RECEPTOR; NEUROTENSIN TYPE 1 RECEPTOR; SMALL INTERFERING RNA;

ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL PROLIFERATION; CONFOCAL MICROSCOPY; CYTOLOGY; ENZYME IMMUNOASSAY; FLOW CYTOMETRY; GENETICS; HEK293 CELL LINE; HUMAN; IMMUNOPRECIPITATION; METABOLISM; PHOSPHORYLATION; PROTEIN MULTIMERIZATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; FLOW CYTOMETRY; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HEK293 CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IMMUNOENZYME TECHNIQUES; IMMUNOPRECIPITATION; MICROSCOPY, CONFOCAL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; PROTEIN MULTIMERIZATION; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROTENSIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84908053927     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.12404     Document Type: Article

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