Providing rapid out of hospital acute cardiovascular treatment 3 (PROACT-3)

Canadian Journal of Cardiology

Volumn 30, Issue 10, 2014, Pages 1208-1215

  Ezekowitz, Justin A ^a,b   Welsh, Robert C ^a,b   Gubbels, Courtney ^a   Brass, Neil ^c   Chan, Michael ^c   Keeble, William ^d   Khadour, Fadi ^e   Koshy, Thomas L ^f   Knapp, Darren ^g   Sharma, Sanjay ^h   Sookram, Sunil ⁱ   Tymchak, Wayne ^a,b   Weiss, Dale ^g   Westerhout, Cynthia M ^a   Armstrong, Paul W ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b MAZANKOWSKI ALBERTA HEART INSTITUTE   (Canada)

^c ROYAL ALEXANDRA HOSPITAL   (Canada)

^d Misericordia Community Hospital   (Canada)

^e Sturgeon Hospital   (Canada)

^f SolidBase Consulting and Development   (Canada)

^g ALBERTA HEALTH SERVICES   (Canada)

^h GREY NUNS COMMUNITY HOSPITAL   (Canada)

ⁱ UNIVERSITY OF ALBERTA HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBOCYTIC AGENT; BRAIN NATRIURETIC PEPTIDE; FIBRINOGEN RECEPTOR ANTAGONIST; FUROSEMIDE; GLYCERYL TRINITRATE; LOW MOLECULAR WEIGHT HEPARIN; TROPONIN I; BIOLOGICAL MARKER; TROPONIN;

ACUTE CORONARY SYNDROME; ADULT; AGED; AORTA DISSECTION; ARTICLE; ASTHMA; CARDIOVASCULAR SYMPTOM; CHOLECYSTITIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DIABETES MELLITUS; DIAGNOSTIC TEST ACCURACY STUDY; DYSPNEA; EMERGENCY HEALTH SERVICE; EMERGENCY TREATMENT; EMERGENCY WARD; FEMALE; GASTROESOPHAGEAL REFLUX; HEALTH CARE QUALITY; HEART ARRHYTHMIA; HUMAN; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; MYOCARDITIS; NON ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; PANCREATITIS; PERICARDITIS; PREDICTIVE VALUE; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT INFECTION; SENSITIVITY AND SPECIFICITY; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; THORAX PAIN; TIME TO TREATMENT; TREATMENT OUTCOME; UNSTABLE ANGINA PECTORIS; BLOOD; EARLY TERMINATION OF CLINICAL TRIAL; HEART FAILURE; HOSPITAL INFORMATION SYSTEM; HOSPITALIZATION; INTENTION TO TREAT ANALYSIS; STATISTICS AND NUMERICAL DATA;

ACUTE CORONARY SYNDROME; AGED; BIOLOGICAL MARKERS; EARLY TERMINATION OF CLINICAL TRIALS; EMERGENCY MEDICAL SERVICES; EMERGENCY SERVICE, HOSPITAL; FEMALE; HEART FAILURE; HOSPITALIZATION; HUMANS; INTENTION TO TREAT ANALYSIS; MALE; NATRIURETIC PEPTIDE, BRAIN; POINT-OF-CARE SYSTEMS; TROPONIN;

EID: 84908030819     PISSN: 0828282X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cjca.2014.04.012     Document Type: Article

References (29)

1. Thygesen K., Alpert J.S., Jaffe A.S., et al. Third universal definition of myocardial infarction. JAm Coll Cardiol 2012, 60:1581-1598.
2. Mehta R.H., Eagle K.A. Missed diagnoses of acute coronary syndromes in the emergency room-continuing challenges. NEngl J Med 2000, 342:1207-1210.
3. Ezekowitz J.A., Bakal J.A., Kaul P., Westerhout C.M., Armstrong P.W. Acute heart failure in the emergency department: short and long-term outcomes of elderly patients with heart failure. Eur J Heart Fail 2008, 10:308-314.
4. Farkouh M.E., Smars P.A., Reeder G.S., et al. Aclinical trial of a chest-pain observation unit for patients with unstable angina. Chest Pain Evaluation in the Emergency Room (CHEER) Investigators. NEngl J Med 1998, 339:1882-1888.
5. Hugli O., Braun J.E., Kim S., Pelletier A.J., Camargo C.A. United States emergency department visits for acute decompensated heart failure, 1992 to 2001. Am J Cardiol 2005, 96:1537-1542.
6. Reichlin T., Hochholzer W., Bassetti S., et al. Early diagnosis of myocardial infarction with sensitive cardiac troponin assays. NEngl J Med 2009, 361:858-867.
7. Armstrong P.W., Westerhout C.M., Welsh R.C. Duration of symptoms is the key modulator of the choice of reperfusion for ST-elevation myocardial infarction. Circulation 2009, 119:1293-1303.
8. Apple F.S., Collinson P.O. Analytical characteristics of high-sensitivity cardiac troponin assays. Clin Chem 2011, 58:54-61. for the IFCC Task Force on Clinical Applications of Cardiac Biomarkers.
9. Than M., Cullen L., Aldous S., et al. 2-Hour Accelerated Diagnostic Protocol to Assess Patients With Chest Pain Symptoms Using Contemporary Troponins as the Only Biomarker: the ADAPT Trial. JAm Coll Cardiol 2012, 59:2091-2098.
10. Sørensen J.T., Terkelsen C.J., Steengaard C., et al. Prehospital troponin T testing in the diagnosis and triage of patients with suspected acute myocardial infarction. Am J Cardiol 2011, 107:1436-1440.
11. Roth A., Malov N., Golovner M., et al. The "SHAHAL" experience in Israel for improving diagnosis of acute coronary syndromes in the prehospital setting. Am J Cardiol 2001, 88:608-610.
12. Leshem-Rubinow E., Abramowitz Y., Malov N., et al. Prehospital cardiac markers in defining ambiguous chest pain. Arch Intern Med 2011, 171:2056-2057.
13. Newman J., Aulick N., Cheng T., et al. Prehospital identification of acute coronary ischemia using a troponin T rapid assay. Prehosp Emerg Care 1999, 3:97-101.
14. Schuchert A., Hamm C., Scholz J., et al. Prehospital testing for troponin T in patients with suspected acute myocardial infarction. Am Heart J 1999, 138:45-48.
15. Maisel A.S., Krishnaswamy P., Nowak R.M., et al. Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure. NEngl J Med 2002, 347:161-167.
16. Januzzi J.L. NT-proBNP testing for diagnosis and short-term prognosis in acute destabilized heart failure: an international pooled analysis of 1256 patients: the International Collaborative of NT-proBNP Study. Eur Heart J 2005, 27:330-337.
17. Moe G.W., Howlett J., Januzzi J.L., Zowall H. N-terminal pro-B-type natriuretic peptide testing improves the management of patients with suspected acute heart failure: primary results of the Canadian prospective randomized multicenter IMPROVE-CHF Study. Circulation 2007, 115:3103-3110. for the Canadian Multicenter Improved Management of Patients With Congestive Heart Failure (IMPROVE-CHF) Study Investigators.
18. Teboul A., Gaffinel A., Meune C., et al. Management of acute dyspnoea: use and feasibility of brain natriuretic peptide (BNP) assay in the prehospital setting. Resuscitation 2004, 61:91-96.
19. Arnold J.M., Howlett J.G., Dorian P., et al. Canadian Cardiovascular Society Consensus Conference recommendations on heart failure update 2007: prevention, management during intercurrent illness or acute decompensation, and use of biomarkers. Can J Cardiol 2007, 23:21-45.
20. Yancy C.W., Jessup M., Bozkurt B., et al. 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 2013, 128:e240-327.
21. McMurray J.J., Adamopoulos S., Anker S.D., et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J 2012, 33:1787-1847. [erratum in 2013;34:158].
22. Triage Cardio3 Panel, Triage Cardio2 Panel, Triage Troponin I Test.Available at: . Accessed September 3, 2013. http://www.alere.ca/pdf/Triage-Cardio-Kit-EN-PI.pdf.
23. Maisel A.S., Peacock W.F., McMullin N., et al. Timing of immunoreactive B-type natriuretic peptide levels and treatment delay in acute decompensated heart failure: an ADHERE (Acute Decompensated Heart Failure National Registry) analysis. JAm Coll Cardiol 2008, 52:534-540.
24. De Luca G., Suryapranata H., Ottervanger J.P., Antman E.M. Time delay to treatment and mortality in primary angioplasty for acute myocardial infarction: every minute of delay counts. Circulation 2004, 109:1223-1225.
25. Ryan R.J., Lindsell C.J., Hollander J.E., et al. Amulticenter randomized controlled trial comparing central laboratory and point-of-care cardiac marker testing strategies: the Disposition Impacted by Serial Point of Care Markers in Acute Coronary Syndromes (DISPO-ACS) trial. Ann Emerg Med 2009, 53:321-328.
26. Goodacre S.W., Bradburn M., Cross E., et al. The Randomised Assessment of Treatment using Panel Assay of Cardiac Markers (RATPAC) trial: a randomised controlled trial of point-of-care cardiac markers in the emergency department. Heart 2011, 97:190-196.
27. Antman E.M., Cohen M., Bernink P.J., et al. The TIMI risk score for unstable angina/non-ST elevation MI: a method for prognostication and therapeutic decision making. JAMA 2000, 284:835-842.
28. Than M., Cullen L., Reid C.M., et al. A2-h diagnostic protocol to assess patients with chest pain symptoms in the Asia-Pacific region (ASPECT): a prospective observational validation study. Lancet 2011, 377:1077-1084.
29. Fox K.A., Dabbous O.H., Goldberg R.J., et al. Prediction of risk of death and myocardial infarction in the six months after presentation with acute coronary syndrome: prospective multinational observational study (GRACE). BMJ 2006, 333:1091.