Bacterial biofilm formation and treatment in soft tissue fillers

Pathogens and Disease

Volumn 70, Issue 3, 2014, Pages 339-346

  Alhede, Morten ^a,b   Er, Özge ^a   Eickhardt, Steffen ^a   Kragh, Kasper ^a   Alhede, Maria ^a   Christensen, Louise Dahl ^a   Poulsen, Steen Seier ^c   Givskov, Michael ^a,d   Christensen, Lise H ^c   Høiby, Niels ^a,b   Tvede, Michael ^b   Bjarnsholt, Thomas ^a,b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b Rigshospitalet   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

Biofilm; Calcium hydroxyl apatite microspheres; Hyaluronic acid gel; Polyacrylamide hydrogel; Prophylactic treatment; Soft tissue fillers

Indexed keywords

COLISTIN; HYALURONIC ACID; HYDROXYAPATITE; MICROSPHERE; POLYACRYLAMIDE; RIFAMPICIN; TOBRAMYCIN; TRIAMCINOLONE ACETONIDE; VANCOMYCIN; ANTIINFECTIVE AGENT; BIOMATERIAL; HYDROGEL;

ANIMAL EXPERIMENT; ARTICLE; BACTERIAL GROWTH; BACTERIAL INFECTION; BACTERIUM CULTURE; BIOFILM; CONTROLLED STUDY; FEMALE; GEL; HYDROGEL; INJECTABLE IMPLANT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROPIONIBACTERIUM ACNES; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS EPIDERMIDIS; ANIMAL; BACTERIA; BACTERIAL PHENOMENA AND FUNCTIONS; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; MICROBIOLOGY; PHYSIOLOGY; PSEUDOMONAS INFECTIONS;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIA; BACTERIAL PHYSIOLOGICAL PHENOMENA; BIOCOMPATIBLE MATERIALS; BIOFILMS; FEMALE; HYDROGELS; MICE; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS;

EID: 84908027830     PISSN: None     EISSN: 2049632X     Source Type: Journal    
DOI: 10.1111/2049-632X.12139     Document Type: Article

References (25)

1. Alhede M, Kragh KN, Qvortrup K et al. (2011) Phenotypes of non-attached Pseudomonas aeruginosa aggregates resemble surface attached biofilm. PLoS ONE 6: e27943.
2. Alijotas-Reig J & Garcia-Gimenez V (2011) Adverse reactions caused by different filler injections in the same region. J Eur Acad Dermatol Venereol 25: 736-737.
3. Alijotas-Reig J, Miro-Mur F, Planells-Romeu I, Garcia-Aranda N, Garcia-Gimenez V & Vilardell-Tarres M (2010) Are bacterial growth and/or chemotaxis increased by filler injections? Implications for the pathogenesis and treatment of filler-related granulomas. Dermatology 221: 356-364.
4. Bachmann F, Erdmann R, Hartmann V, Becker-Wegerich P, Wiest L & Rzany B (2011) Adverse reactions caused by consecutive injections of different fillers in the same facial region: risk assessment based on the results from the Injectable Filler Safety study. J Eur Acad Dermatol Venereol 25: 902-912.
5. Barber FA & Dockery WD (2006) Long-term absorption of poly-L-lactic Acid interference screws. Arthroscopy 22: 820-826.
6. Bjarnsholt T, Jensen PO, Burmolle M et al. (2005) Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent. Microbiology 151: 373-383.
7. Bjarnsholt T, Tolker-Nielsen T, Givskov M, Janssen M & Christensen LH (2009) Detection of bacteria by fluorescence in situ hybridization in culture-negative soft tissue filler lesions. Dermatol Surg 35(suppl 2): 1620-1624.
8. Brahm J, Lessel R, Ditlev S & Schmidt R (2011) Flux of selected body fluid constituents and benzylpenicillin in polyacrylamide hydrogel (PAAG). J Tissue Eng Regen Med 6: 793-802.
9. Christensen L (2007) Normal and pathologic tissue reactions to soft tissue gel fillers. Dermatol Surg 33(suppl 2): S168-S175.
10. Christensen LH (2009) Host tissue interaction, fate, and risks of degradable and nondegradable gel fillers. Dermatol Surg 35 (suppl 2): 1612-1619.
11. Christensen L, Breiting V, Janssen M, Vuust J & Hogdall E (2005) Adverse reactions to injectable soft tissue permanent fillers. Aesthetic Plast Surg 29: 34-48.
12. Christensen K, Vang S, Brady C, Isler J, Allen K, Anderson J & Holt D (2006) Autologous platelet gel: an in vitro analysis of platelet-rich plasma using multiple cycles. J Extra Corpor Technol 38: 249-253.
13. Christensen LH, Nielsen JB, Mouritsen L, Sorensen M & Lose G (2008) Tissue integration of polyacrylamide hydrogel: an experimental study of periurethral, perivesical, and mammary gland tissue in the pig. Dermatol Surg 34(suppl 1): S68-S77; discussion S77.
14. Christensen L, Breiting V, Bjarnsholt T et al. (2013) Bacterial infection as a likely cause of adverse reactions to polyacrylamide hydrogel fillers in cosmetic surgery. Clin Infect Dis 56: 1438- 1444.
15. de Maio M (2004) The minimal approach: an innovation in facial cosmetic procedures. Aesthetic Plast Surg 28: 295-300.
16. Herrmann G, Yang L, Wu H et al. (2010) Colistin-tobramycin combinations are superior to monotherapy concerning the killing of biofilm Pseudomonas aeruginosa. J Infect Dis 202: 1585- 1592.
17. Klein AW & Elson ML (2000) The history of substances for soft tissue augmentation. Dermatol Surg 26: 1096-1105.
18. Mack D, Siemssen N & Laufs R (1992) Parallel induction by glucose of adherence and a polysaccharide antigen specific for plastic- adherent Staphylococcus epidermidis: evidence for functional relation to intercellular adhesion. Infect Immun 60: 2048-2057.
19. Morhenn VB, Lemperle G & Gallo RL (2002) Phagocytosis of different particulate dermal filler substances by human macrophages and skin cells. Dermatol Surg 28: 484-490.
20. Narins RS & Bowman PH (2005) Injectable skin fillers. Clin Plast Surg 32: 151-162.
21. Pamp SJ, Gjermansen M, Johansen HK & Tolker-Nielsen T (2008) Tolerance to the antimicrobial peptide colistin in Pseudomonas aeruginosa biofilms is linked to metabolically active cells, and depends on the pmr and mexAB-oprM genes. Mol Microbiol 68: 223-240.
22. Rohrich RJ, Rios JL & Fagien S (2003) Role of new fillers in facial rejuvenation: a cautious outlook. Plast Reconstr Surg 112: 1899- 1902.
23. Sperling B, Bachmann F, Hartmann V, Erdmann R, Wiest L & Rzany B (2010) The current state of treatment of adverse reactions to injectable fillers. Dermatol Surg 36(suppl 3): 1895- 1904.
24. Tzikas TL (2008) A 52-month summary of results using calcium hydroxylapatite for facial soft tissue augmentation. Dermatol Surg 34(suppl 1): S9-S15.
25. Van Gennip M, Christensen LD, Alhede M et al. (2009) Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes. APMIS 117: 537-546.