Inhibitory mechanism of dimercaptopropanesulfonic acid (DMPS) in the cellular biomethylation of arsenic

Biochimie

Volumn 106, Issue , 2014, Pages 167-174

  Wang, Shuping ^a   Shi, Nan ^a   Geng, Zhirong ^a   Li, Xiangli ^a   Hu, Xin ^b   Wang, Zhilin ^a  

^a NANJING UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

Author keywords

Arsenic; Biomethylation; DMPS; Inhibition; Mechanism

Indexed keywords

ARSENIC; ARSENIC METHYLTRANSFERASE; DIMERCAPTOPROPANESULFONIC ACID; METHYLTRANSFERASE; REACTIVE OXYGEN METABOLITE; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; ANTIDOTE; MONOMETHYLARSONOUS ACID; ORGANOMETALLIC COMPOUND; UNITHIOL;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG DETOXIFICATION; DRUG ELIMINATION; DRUG INHIBITION; DRUG METABOLISM; ENZYME ACTIVITY; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; METHYLATION; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; ARSENIC POISONING; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION; GENETICS; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANTIDOTES; APOPTOSIS; ARSENIC; ARSENIC POISONING; BLOTTING, WESTERN; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; HEP G2 CELLS; HUMANS; METHYLATION; METHYLTRANSFERASES; ORGANOMETALLIC COMPOUNDS; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; UNITHIOL;

EID: 84908019297     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2014.08.017     Document Type: Article

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