Diagnoses, procedures, drug utilization, comorbidities, and cost of health care for people with epilepsy in 2012

Epilepsy and Behavior

Volumn 41, Issue , 2014, Pages 83-90

  Wilner, A N ^a   Sharma, B K ^b   Thompson, A ^b   Soucy, A ^b   Krueger, A ^b  

^a Lawrence and Memorial Hospital   (United States)

^b Accordant Health Services   (United States)

Author keywords

Comorbidities; Drugs; Epilepsy; Medical claims; Procedures; Seizure

Indexed keywords

AMOXICILLIN; ANALGESIC AGENT; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ANTIHYPERTENSIVE AGENT; ANXIOLYTIC AGENT; AZITHROMYCIN; CITALOPRAM; CLONAZEPAM; DRUG; ETIRACETAM; FLUTICASONE PROPIONATE; HYDROCODONE; LAMOTRIGINE; MACROLIDE; OMEPRAZOLE; OPIATE; OXYCODONE; PARACETAMOL; PENICILLIN DERIVATIVE; PENICILLIN V POTASSIUM; PHENYTOIN; PREDNISONE; PRESCRIPTION DRUG; PSEUDOMONIC ACID; SERTRALINE; TOPIRAMATE; TRAZODONE; TRIAMCINOLONE ACETONIDE; UNINDEXED DRUG;

ADULT; ARTICLE; BLOOD CELL COUNT; COMORBIDITY; COMPLEX PARTIAL SEIZURE; COMPUTER ASSISTED TOMOGRAPHY; CONVULSION; DRUG UTILIZATION; ELECTROCARDIOGRAPHY; EMERGENCY WARD; EPILEPSY; FEMALE; HEALTH CARE COST; HEALTH INSURANCE; HOSPITAL PATIENT; HUMAN; IMMUNIZATION; INTRACTABLE EPILEPSY; MAJOR CLINICAL STUDY; MALE; PREVALENCE; RESOURCE ALLOCATION; SEIZURE; THORAX PAIN; THORAX RADIOGRAPHY; ULCER; ADOLESCENT; AGED; CHILD; ECONOMICS; INFANT; MIDDLE AGED; PRESCHOOL CHILD; STATISTICS AND NUMERICAL DATA; UNITED STATES; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHILD; CHILD, PRESCHOOL; COMORBIDITY; DRUG UTILIZATION; EPILEPSY; FEMALE; HEALTH CARE COSTS; HUMANS; INFANT; INSURANCE, HEALTH; MALE; MIDDLE AGED; UNITED STATES; YOUNG ADULT;

EID: 84908006680     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2014.08.131     Document Type: Article

References (29)

1. Fisher R.S., van Emde Boas W., Blume W., Elger C., Genton P., Lee P., et al. Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE). Epilepsia 2005, 46(4):470-472.
2. Begley C.E., Famulari M., Annegers J.F., Lairson D.R., Reynolds T.F., Coan S., et al. The cost of epilepsy in the United States: an estimate from population-based clinical and survey data. Epilepsia 2000, 41(3):342-351.
3. Ivanova J.I., Birnbaum H.G., Kidolezi Y., Qiu Y., Mallett D., Caleo S. Economic burden of epilepsy among the privately insured in the US. Pharmacoeconomics 2010, 28(8):675-685.
4. Wilner A.N., Sharma B.K., Soucy A., Krueger A. Health plan paid cost of epilepsy in 2009 in the U.S. Epilepsy Behav 2012, 25:412-416.
5. Begley C.E., Lairson D.R., Reynolds T.F., Coan S. Early treatment cost in epilepsy and how it varies with seizure type and frequency. Epilepsy Res 2001, 47:205-215.
6. Manjunath R., Paradis P.E., Parise H., Lafeuille M.H., Bowers B., Duh M.S., et al. Burden of uncontrolled epilepsy in patients requiring an emergency room visit or hospitalization. Neurology 2012, 79:1908-1916.
7. Vivas A.C., Baaj A.A., Benbadis S.R., Vale F.L. The health care burden of patients with epilepsy in the United States: an analysis of a nationwide database over 15years. Neurosurg Focus 2012, 32(3):E1. 10.3171/2012.1.FOCUS11322.
8. Cramer J.A., Wang Z.J., Chang E., Powers A., Copher R., Cherepanov D., et al. Healthcare utilization and costs in adults with stable and uncontrolled epilepsy. Epilepsy Behav 2014, 31:356-362.
9. Cardarelli W.J., Smith B.J. The burden of epilepsy to patients and payers. Am J Manag Care 2010, 16:S331-S336.
10. Cramer J.A., Blum D., Fanning K., Reed M., Epilepsy Impact Project Group The impact of comorbid depression on health resource utilization in a community sample of people with epilepsy. Epilepsy Behav 2004, 337-342.
11. Wilner A.N., Sharma B.K., Soucy A., Thompson A., Krueger A. Common comorbidities in women and men with epilepsy and the relationship between number of comorbidities and health plan paid costs in 2010. Epilepsy Behav 2014, 32:15-20.
12. Gaitatzis A., Sisodiya S.M., Sander J.W. The somatic comorbidity of epilepsy: a weighty but often unrecognized burden. Epilepsia 2012, 53(8):1282-1293.
13. Feinstein A.R. The pre-therapeutic classification of co-morbidity in chronic disease. J Chronic Dis 1970, 23:455-468.
14. Pugliatti M., Beghi E., Forsgren L., Ekman M., Sobocki P. Estimating the cost of epilepsy in Europe: a review with economic modeling. Epilepsia 2007, 48:2224-2233.
15. Goldenberg M.M. Overview of drugs used for epilepsy and seizures. Proc Natl Acad Sci U S A 2010, 35:392-415.
16. Christensen J., Kjeldsen M.J., Andersen H., Friis M.L., Sidenius P. Gender differences in epilepsy. Epilepsia 2005, 46(6):956-960.
17. Kadima N.T., Kobau R., Zack M.M., Helmers S. Comorbidity in adults with epilepsy-United States, 2010. MMWR Morb Mortal Wkly Rep 2013, 62(43):849-853.
18. Kessler R.C., Lane M.C., Shahly V., Stang P.E. Accounting for comorbidity in assessing the burden of epilepsy among US adults: results from the National Comorbidity Survey Replication (NCS-R). Mol Psychiatry 2012, 17:748-758.
19. Lee W.C., Arcona S., Thomas S.K., Wang Q., Hoffmann M.S., Pashos C.L. Effect of comorbidities on medical care use and cost among refractory patients with partial seizure disorder. Epilepsy Behav 2005, 7:123-126.
20. St.Germaine-Smith C., Liu M., Quan H., Wiebe S., Jette N. Development of an epilepsy-specific risk adjustment comorbidity index. Epilepsia 2011, 52:2161-2167.
21. Institute of Medicine Epilepsy across the spectrum: promoting health and understanding 2012, [Internet], The National Academies Press, Washington, [[Accessed 2014 May 14] at: http://www.ncbi.nlm.nih.gov/books/NBK91506/].
22. Tellez-Zenteno J.F., Patten S.B., Jetté N., Williams J., Wiebe S. Psychiatric comorbidity in epilepsy: a population-based analysis. Epilepsia 2007, 48(12):2336-2344.
23. Gaitatzis A., Carroll K., Majeed A., Sander J. The epidemiology of the comorbidity of epilepsy in the general population. Epilepsia 2004, 45(12):1613-1622.
24. Fazel S., Wolf A., Langstrom N., Newton C.R., Lichtenstein P. Premature mortality in epilepsy and the role of psychiatric comorbidity: a total population study. Lancet 2013, 382(9905):1646-1654.
25. Ottman R., Lipton R.B., Ettinger A.B., Cramer J.A., Reed M.L., Morrison A., et al. Comorbidities of epilepsy: results from the Epilepsy Comorbidities and Health (EPIC) survey. Epilepsia 2011, 52(2):308-315.
26. Wolff J.L., Starfield B., Anderson G. Prevalence, expenditures, and complications of multiple chronic conditions. Arch Intern Med 2002, 162:2269-2276.
27. LaFrance W.C., Benbadis S.R. Avoiding the costs of unrecognized psychological nonepileptic seizures. Neurology 2006, 66:1620-1621.
28. Bonavita V., De Simone R. Towards a definition of comorbidity in the light of clinical complexity. Neurol Sci 2008, 29:S99-S102.
29. Valderas J.M., Starfield B., Sibbald B., Salisbury C., Ronald M. Defining comorbidity: implications for understanding health and health services. Ann Fam Med 2009, 7:357-363.