SMILE upregulated by metformin inhibits the function of androgen receptor in prostate cancer cells

Cancer Letters

Volumn 354, Issue 2, 2014, Pages 390-397

  Lee, Seung Yon ^a   Song, Chin Hee ^a   Xie, Yuan Bin ^a   Jung, Chaeyong ^b   Choi, Hueng Sik ^a   Lee, Keesook ^a  

^a Chonnam National University   (South Korea)

^b Chonnam National University Medical School   (South Korea)

Author keywords

Androgen receptor; Corepressor; Metformin; Prostate cancer cells; SMILE

Indexed keywords

ANDROGEN RECEPTOR; CELL NUCLEUS RECEPTOR; METFORMIN; REGULATOR PROTEIN; SHORT HAIRPIN RNA; SMALL HETERODIMER PARTNER INTERACTING LEUCINE ZIPPER PROTEIN; UNCLASSIFIED DRUG; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; CREBZF PROTEIN, HUMAN;

ARTICLE; CANCER CELL; CANCER INHIBITION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GENETIC TRANSFECTION; HEK293 CELL LINE; HUMAN; HUMAN CELL; LNCAP CELL LINE; NKX3.1 GENE; NORTHERN BLOTTING; PLASMID; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN FUNCTION; PSA GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CELL GROWTH; DRUG EFFECTS; GENETICS; MALE; METABOLISM; MOUSE; NEOPLASMS, HORMONE-DEPENDENT; PHYSIOLOGY; PROSTATIC NEOPLASMS; TRANSCRIPTION INITIATION; TUMOR CELL LINE;

ANIMALS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL GROWTH PROCESSES; CELL LINE, TUMOR; HEK293 CELLS; HUMANS; MALE; METFORMIN; MICE; NEOPLASMS, HORMONE-DEPENDENT; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 84908005181     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.09.001     Document Type: Article

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