Cross-reactivity and tolerability of cephalosporins in patients with cell-mediated allergy to penicillins

Journal of Investigational Allergology and Clinical Immunology

Volumn 24, Issue 5, 2014, Pages 331-337

  Buonomo, Alessandro ^a   Nucera, E ^a   Pecora, V ^a   Rizzi, A ^a   Aruanno, A ^a   Pascolini, L ^a   Ricci, A G ^a   Colagiovanni, A ^a   Schiavino, D ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

Cell mediated hypersensitivity; Cephalosporins; Cross reactivity; Penicillins

Indexed keywords

AMINOPENICILLIN; AMOXICILLIN; AMPICILLIN; AZTREONAM; CEFACLOR; CEFALEXIN; CEFUROXIME AXETIL; CEPHALOSPORIN; CILASTATIN PLUS IMIPENEM; CLAVULANIC ACID; CLOXACILLIN; IMMUNOGLOBULIN E; MEZLOCILLIN; PENICILLIN DERIVATIVE; PENICILLIN G; PIPERACILLIN; SULBACTAM; TICARCILLIN; CEPHALOSPORIN DERIVATIVE;

ADOLESCENT; AGED; ANGIONEUROTIC EDEMA; ARTICLE; BLOOD ANALYSIS; CONTACT DERMATITIS; CROSS REACTION; DELAYED HYPERSENSITIVITY; DRUG TOLERABILITY; ERYTHEMA; ERYTHEMA MULTIFORME; HUMAN; MACULOPAPULAR RASH; MAJOR CLINICAL STUDY; PATCH TEST; PROVOCATION TEST; PRURITUS; SKIN TEST; STEVENS JOHNSON SYNDROME; URTICARIA; ADULT; DRUG HYPERSENSITIVITY; FEMALE; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; MALE; MIDDLE AGED;

ADULT; AGED; CEPHALOSPORINS; CROSS REACTIONS; DRUG HYPERSENSITIVITY; FEMALE; HUMANS; IMMUNE TOLERANCE; MALE; MIDDLE AGED; PENICILLINS;

EID: 84908004593     PISSN: 10189068     EISSN: 16980808     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Liu XD, Gao N, Qiao HL. Cephalosporin and penicillin crossreactivity in patients allergic to penicillins. Int J Clin Pharmacol Ther. 2011; 49: 206-16.
2. Romano A, Guéant-Rodriguez RM, Viola M, Pettinato R, Guéant JL. Cross-reactivity and tolerability of cephalosporins in patients with immediate hypersensitivity to penicillins. Ann Intern Med. 2004; 141: 16-22.
3. Park MA, Koch CA, Klemawesch P, Joshi A, Li JT. Increased adverse drug reactions to cephalosporins in penicillin allergy patients with positive penicillin skin test. Int Arch Allergy Immunol. 2010; 153: 268-73.
4. Kelkar PS, Li JTC. Cephalosporin allergy N Engl J Med. 2001; 345: 804-9.
5. Patriarca G, D’Ambrosio C, Schiavino D, Larocca LM, Nucera E, Milani A. Clinical usefulness of patch and challenge tests in the diagnosis of cell-mediated allergy to betalactams. Ann Allergy Asthma Immunol. 1999; 83: 257-66.
6. Phillips E, Knowles SR, Weber EA, Blackburn D. Cephalexin tolerated despite delayed aminopenicillin reactions. Allergy. 2001; 56: 790.
7. Trcka J, Seitz CS, Bröcker E-B, Gross GE, Trautmann A. Aminopenicillin-induced exanthema allows treatment with certain cephalosporins or phenoxymethyl penicillin. J Antimicrob Chemother. 2007; 60: 107-11.
8. Patriarca G, D’Ambrosio C, Schiavino D, Nucera E, Sun JY, Del Ninno M, Misuraca C, Buonomo A. Allergy to betalactams. Where are we going? Int Arch Allergy Immunol. 1999; 118: 247-50.
9. Brockow K, Romano A, Blanca M, Ring J, Pichler W, Demoly P. General considerations for skin test procedures in the diagnosis of drug hypersensitivity. Allergy. 2002; 57: 45-51.
10. Torres MJ, Blanca M, Fernandez J, Romano A, de Weck A, Aberer W, Brockow K, Pichler WJ, Demoly P, for ENDA and the EAACI interest group on drug hypersensitivity. Diagnosis of immediate allergic reactions to beta-lactam antibiotics Allergy. 2003; 58: 961-72.
11. Romano A, Viola M, Bousquet PJ, Gaeta F, Valluzzi R, Caruso C, Demoly P. A comparison of the performance of two penicillin reagent kits in the diagnosis of b-lactam hypersensitivity. Allergy. 2007; 62: 53-8.
12. Torres MJ, Sánchez-Sabaté E, Álvarez J, Mayorga C, Fernández J, Padial A, Cornejo-García JA, Bellón T, Blanca M. Skin test evaluation in nonimmediate allergic reactions to penicillins. Allergy. 2004; 59: 219-24.
13. Schiavino D, Nucera E, Lombardo C, Decinti M, Pascolini L, Altomonte G, Buonomo A, Patriarca G. Cross-reactivity and tolerability of imipenem in patients with delayed-type, cellmediated hypersensitivity to b-lactams. Allergy. 2009; 64: 1644-48.
14. Buonomo A, Nucera E, De Pasquale T, Pecora V, Lombardo C, Sabato V, Colagiovanni A, Rizzi A, Aruanno A, Pascolini L, Patriarca G, Schiavino D. Tolerability of aztreonam in patients with cell-mediated allergy to β-lactams. Int Arch Allergy Immunol. 2011; 155: 155-9.
15. Novalbos A, Sastre J, Cuesta J, De Las Heras M, Lluch-Bernal M, Bombín C, Quirce S. Lack of allergic cross-reactivity to cephalosporins among patients allergic to penicillins. Clin Exp Allergy. 2001; 31: 438-43.
16. Caimmi S, Galéra C, Bousquet-Rouanet L, Arnoux B, Demoly P, Bousquet PJ. Safety of cefuroxime as an alternative in patients with a proven hypersensitivity to penicillins: a DAHD cohort survey. Int Arch Allergy Immunol. 2010; 153: 53-60.
17. Phillips E, Knowles SR, Weber EA, Blackburn D. Cephalexin tolerated despite delayed aminopenicillin reactions. Allergy. 2001; 56:790.
18. Atanasković-Marković M, Ćirković Veličković T, Gavrović-Jankulović M, Vučković O, Nestorović B. Immediate allergic reactions to cephalosporins and penicillins and their crossreactivity in children. Pediatr Allergy Immunol. 2005; 16: 341-7.
19. Trcka J, Seitz CS, Bröcker EB, Gross GE, Trautmann A. Aminopenicillin-induced exanthema allows treatment with certain cephalosporins or phenoxymethyl penicillin. J Antimicrob Chemother. 2007; 60: 107-111.
20. Perez-Inestrosa E, Suau R, Montañez MI, Rodriguez R, Mayorga C, Torres MJ, Blanca M. Cephalosporin chemical reactivity and its immunological implications. Curr Opin Allergy Clin Immunol. 2005; 5: 323-30.
21. Pichichero ME, Casey JR. Safe use of selected cephalosporins in penicillin-allergic patients: a meta-analysis. Otolaryngol Head Neck Surg. 2007; 136: 340-7.
22. Campagna JD, Bond MC, Schabelman E, Hayes BD. The use of cephalosporins in penicillin-allergic patients: a literature review. J Emerg Med. 2012; 42: 612-20.