Effects of bone marrow mononuclear cells from healthy or ovalbumin-induced lung inflammation donors on recipient allergic asthma mice

Stem Cell Research and Therapy

Volumn 5, Issue 5, 2014, Pages

  Abreu, Soraia C ^a   Antunes, Mariana A ^a   Mendonça, Lucas ^a   Branco, Vivian C ^a   De Melo, Elga Bandeira ^a   Olsen, Priscilla C ^a   Diaz, Bruno L ^a   Weiss, Daniel J ^b   Paredes, Bruno D ^a   Xisto, Debora G ^a   Morales, Marcelo M ^a   Rocco, Patricia R M ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; OVALBUMIN; SODIUM CHLORIDE; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

AIRWAY REMODELING; AIRWAY RESISTANCE; ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATELECTASIS; BONE MARROW DERIVED MONONUCLEAR CELL; BRONCHOCONSTRICTION; CELL INFILTRATION; CELL TRANSPLANTATION; COLLAGEN FIBER; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EOSINOPHIL COUNT; FEMALE; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; HISTOPATHOLOGY; LEUKOCYTE COUNT; LUNG ALVEOLAR COLLAPSE; LUNG DISEASE; LUNG FUNCTION; LUNG HOMOGENATE; LUNG MECHANICS; MESENCHYMAL STEM CELL; MONOCYTE; MOUSE; NONHUMAN; PNEUMONIA; THERAPY EFFECT; ANIMAL; ASTHMA; BIOLOGICAL THERAPY; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; C57BL MOUSE; CYTOLOGY; DISEASE MODEL; IMMUNOLOGY; IMMUNOPHENOTYPING; MONONUCLEAR CELL; PATHOLOGY; PROCEDURES; RANDOMIZATION; TRANSPLANTATION;

ANIMALS; ASTHMA; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CELL- AND TISSUE-BASED THERAPY; DISEASE MODELS, ANIMAL; FEMALE; IMMUNOPHENOTYPING; LEUKOCYTES, MONONUCLEAR; MICE; MICE, INBRED C57BL; OVALBUMIN; PNEUMONIA; RANDOM ALLOCATION;

EID: 84907993927     PISSN: None     EISSN: 17576512     Source Type: Journal    
DOI: 10.1186/scrt496     Document Type: Article

References (36)

1. Global strategy for the diagnosis and management of asthma in children 5 years and younger. Pedersen SE, Hurd SS, Lemanske RF Jr, Becker A, Zar HJ, Sly PD, Soto-Quiroz M, Wong G, Bateman ED, Pediatr Pulmonol 2011 46 1 17 20963782
2. Remodeling in asthma. Al-Muhsen S, Johnson JR, Hamid Q, J Allergy Clin Immunol 2011 128 451 462 quiz 463-464 10.1016/j.jaci.2011.04.047 21636119
3. Mechanisms of remodeling in asthmatic airways. Shifren A, Witt C, Christie C, Castro M, J Allergy (Cairo) 2012 2012 316 349
4. Novel therapies in asthma: leukotriene antagonists, biologic agents, and beyond. Papierniak ES, Lowenthal DT, Harman E, Am J Ther 2013 20 79 103 10.1097/MJT.0b013e31826915c2 23299231
5. Mesenchymal stromal cells mediate Aspergillus hyphal extract-induced allergic airway inflammation by inhibition of the th17 signaling pathway. Lathrop MJ, Brooks EM, Bonenfant NR, Sokocevic D, Borg ZD, Goodwin M, Loi R, Cruz F, Dunaway CW, Steele C, Weiss DJ, Stem Cells Transl Med 2014 3 194 205 10.5966/sctm.2013-0061 24436442
6. Suppressive effect of compact bone-derived mesenchymal stem cells on chronic airway remodeling in murine model of asthma. Ogulur I, Gurhan G, Aksoy A, Duruksu G, Inci C, Filinte D, Kombak FE, Karaoz E, Akkoc T, Int Immunopharmacol 2014 20 101 109 10.1016/j.intimp.2014.02.028 24613203
7. Bone marrow-derived mesenchymal stromal cells inhibit Th2-mediated allergic airways inflammation in mice. Goodwin M, Sueblinvong V, Eisenhauer P, Ziats NP, LeClair L, Poynter ME, Steele C, Rincon M, Weiss DJ, Stem Cells 2011 29 1137 1148 10.1002/stem.656 21544902
8. Tolerance-like mediated suppression by mesenchymal stem cells in patients with dust mite allergy-induced asthma. Kapoor S, Patel SA, Kartan S, Axelrod D, Capitle E, Rameshwar P, J Allergy Clin Immunol 2012 129 1094 1101 10.1016/j.jaci.2011.10.048 22196773
9. Effects of bone marrow-derived mononuclear cells on airway and lung parenchyma remodeling in a murine model of chronic allergic inflammation. Abreu SC, Antunes MA, Maron-Gutierrez T, Cruz FF, Carmo LG, Ornellas DS, Junior HC, Absaber AM, Parra ER, Capelozzi VL, Morales MM, Rocco PR, Respir Physiol Neurobiol 2011 175 153 163 10.1016/j.resp.2010.10.006 21050897
10. Bone marrow mononuclear cell therapy in experimental allergic asthma: intratracheal versus intravenous administration. Abreu SC, Antunes MA, Maron-Gutierrez T, Cruz FF, Ornellas DS, Silva AL, Diaz BL, Ab'Saber AM, Capelozzi VL, Xisto DG, Morales MM, Rocco PR, Respir Physiol Neurobiol 2013 185 615 624 10.1016/j.resp.2012.11.005 23164835
11. Bone marrow-derived mononuclear cells vs. mesenchymal stromal cells in experimental allergic asthma. Abreu SC, Antunes MA, de Castro JC, de Oliveira MV, Bandeira E, Ornellas DS, Diaz BL, Morales MM, Xisto DG, Rocco PR, Respir Physiol Neurobiol 2013 187 190 198 10.1016/j.resp.2013.03.014 23548824
12. Effect of hypoxia on gene expression of bone marrow-derived mesenchymal stem cells and mononuclear cells. Ohnishi S, Yasuda T, Kitamura S, Nagaya N, Stem Cells 2007 25 1166 1177 10.1634/stemcells.2006-0347 17289933
13. Lung parenchyma remodeling in a murine model of chronic allergic inflammation. Xisto DG, Farias LL, Ferreira HC, Picanco MR, Amitrano D, Lapa ESJR, Negri EM, Mauad T, Carnielli D, Silva LF, Capelozzi VL, Faffe DS, Zin WA, Rocco PR, Am J Respir Crit Care Med 2005 171 829 837 10.1164/rccm.200408-997OC 15657464
14. lung mechanics and histology during sevoflurane anesthesia in a model of chronic allergic asthma. Burburan SM, Xisto DG, Ferreira HC, Riva Ddos R, Carvalho GM, Zin WA, Rocco PR, Anesth Analg 2007 104 631 637 10.1213/01.ane.0000255073.96001.cb 17312222
15. Interrupter resistance elucidated by alveolar pressure measurement in open-chest normal dogs. Bates JH, Ludwig MS, Sly PD, Brown K, Martin JG, Fredberg JJ, J Appl Physiol (1985) 1988 65 408 414 3042744
16. Fish oil has beneficial effects on allergen-induced airway inflammation and hyperreactivity in mice. Bargut TC, Ferreira TP, Daleprane JB, Martins MA, Silva PM, Aguila MB, PLoS One 2013 8 75059 10.1371/journal.pone.0075059 24040386
17. Lung tissue mechanics and extracellular matrix remodeling in acute lung injury. Rocco PR, Negri EM, Kurtz PM, Vasconcellos FP, Silva GH, Capelozzi VL, Romero PV, Zin WA, Am J Respir Crit Care Med 2001 164 1067 1071 10.1164/ajrccm.164.6.2007062 11587998
18. Morphometry: stereological theory and practical methods. Weibel ER, Models of Lung Disease-Microscopy and Structural Methods New York: Marcel Dekker, Gil J, 1990 199 247
19. An official research policy statement of the American Thoracic Society/European Respiratory Society: standards for quantitative assessment of lung structure. Hsia CC, Hyde DM, Ochs M, Weibel ER, Am J Respir Crit Care Med 2010 181 394 418 10.1164/rccm.200809-1522ST 20130146
20. Different strains of mice present distinct lung tissue mechanics and extracellular matrix composition in a model of chronic allergic asthma. Antunes MA, Abreu SC, Damaceno-Rodrigues NR, Parra ER, Capelozzi VL, Pinart M, Romero PV, Silva PM, Martins MA, Rocco PR, Respir Physiol Neurobiol 2009 165 202 207 10.1016/j.resp.2008.12.003 19135181
21. DNA nanoparticle-mediated thymulin gene therapy prevents airway remodeling in experimental allergic asthma. da Silva AL, Martini SV, Abreu SC, Samary CD, Diaz BL, Fernezlian S, de Sa VK, Capelozzi VL, Boylan NJ, Goya RG, Suk JS, Rocco PR, Hanes J, Morales MM, J Control Release 2014 180 125 133 24556417
22. Sex-specific lung remodeling and inflammation changes in experimental allergic asthma. Antunes MA, Abreu SC, Silva AL, Parra-Cuentas ER, Ab'Saber AM, Capelozzi VL, Ferreira TP, Martins MA, Silva PM, Rocco PR, J Appl Physiol (1985) 2010 109 855 863 10.1152/japplphysiol.00333.2010 20634353
23. Stem cell plasticity. Lakshmipathy U, Verfaillie C, Blood Rev 2005 19 29 38 10.1016/j.blre.2004.03.001 15572215
24. IL-5 production by bone marrow stromal cells: implications for eosinophilia associated with asthma. Hogan MB, Piktel D, Landreth KS, J Allergy Clin Immunol 2000 106 329 336 10.1067/mai.2000.108309 10932078
25. Expression of interleukin-5 by human bone marrow microvascular endothelial cells: implications for the regulation of eosinophilopoiesis in vivo. Mohle R, Salemi P, Moore MA, Rafii S, Br J Haematol 1997 99 732 738 10.1046/j.1365-2141.1997.4713279.x 9432015
26. Haemopoietic processes in allergic disease: eosinophil/basophil development. Gauvreau GM, Ellis AK, Denburg JA, Clin Exp Allergy 2009 39 1297 1306 10.1111/j.1365-2222.2009.03325.x 19622087
27. Basophil and eosinophil differentiation in allergic reactions. Denburg JA, Woolley M, Leber B, Linden M, O'Byrne P, J Allergy Clin Immunol 1994 94 1135 1141 10.1016/0091-6749(94)90321-2 7528232
28. Expression of the secondary granule proteins major basic protein 1 (MBP-1) and eosinophil peroxidase (EPX) is required for eosinophilopoiesis in mice. Doyle AD, Jacobsen EA, Ochkur SI, McGarry MP, Shim KG, Nguyen DT, Protheroe C, Colbert D, Kloeber J, Neely J, Shim KP, Dyer KD, Rosenberg HF, Lee JJ, Lee NA, Blood 2013 122 781 790 10.1182/blood-2013-01-473405 23736699
29. Interleukin-12 inhibits eosinophil differentiation from bone marrow stem cells in an interferon-gamma-dependent manner in a mouse model of asthma. Rais M, Wild JS, Choudhury BK, Alam R, Stafford S, Dharajiya N, Sur S, Clin Exp Allergy 2002 32 627 632 10.1046/j.0954-7894.2002.01350.x 11972612
30. Eosinophil differantiation in the bone marrow is inhibited by T cell-derived IFN-γ de Bruin AMBM, van der Sluijs KF, van Gisbergen KP, Boon L, Nolte MA, Blood 2010 116 2559 2569 10.1182/blood-2009-12-261339 20587787
31. Immunosuppressive properties of mesenchymal stem cells: advances and applications. De Miguel MP, Fuentes-Julian S, Blazquez-Martinez A, Pascual CY, Aller MA, Arias J, Arnalich-Montiel F, Curr Mol Med 2012 12 574 591 10.2174/156652412800619950 22515979
32. Immunomodulatory properties of mesenchymal stem cells and their therapeutic applications. Yi T, Song SU, Arch Pharm Res 2012 35 213 221 10.1007/s12272-012-0202-z 22370776
33. Intratracheal transplantation of bone marrow-derived mesenchymal stem cells reduced airway inflammation and up-regulated CD4(+)CD25(+) regulatory T cells in asthmatic mouse. Ge X, Bai C, Yang J, Lou G, Li Q, Chen R, Cell Biol Int 2013 37 675 686 10.1002/cbin.10084 23483727
34. Mesenchymal stem cells derived from human induced pluripotent stem cells modulate T-cell phenotypes in allergic rhinitis. Fu QL, Chow YY, Sun SJ, Zeng QX, Li HB, Shi JB, Sun YQ, Wen W, Tse HF, Lian Q, Xu G, Allergy 2012 67 1215 1222 10.1111/j.1398-9995.2012.02875.x. 22882409
35. Ovalbumin sensitization and challenge increases the number of lung cells possessing a mesenchymal stromal cell phenotype. Bentley JK, Popova AP, Bozyk PD, Linn MJ, Baek AE, Lei J, Goldsmith AM, Hershenson MB, Respir Res 2010 11 127 10.1186/1465-9921-11-127 20858250
36. Myocardial substrate and route of administration determine acute cardiac retention and lung bio-distribution of cardiosphere-derived cells. Bonios M, Terrovitis J, Chang CY, Engles JM, Higuchi T, Lautamaki R, Yu J, Fox J, Pomper M, Wahl RL, Tsui BM, O'Rourke B, Bengel FM, Marban E, Abraham MR, J Nucl Cardiol 2011 18 443 450 10.1007/s12350-011-9369-9 21448759