CD47 blockade reduces ischemia-reperfusion injury and improves outcomes in a rat kidney transplant model

Transplantation

Volumn 98, Issue 4, 2014, Pages 394-401

  Lin, Yiing ^a   Manning, Pamela T ^b   Jia, Jianluo ^a   Gaut, Joseph P ^a   Xiao, Zhenyu ^a   Capoccia, Benjamin J ^a   Chen, Chun Cheng ^a   Hiebsch, Ronald R ^b   Upadhya, Gundumi ^a   Mohanakumar, Thalachallour ^a   Frazier, William A ^a   Chapman, William C ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Vasculox Inc   (United States)

Author keywords

Antibody therapy; Ischemia reperfusion injury; Kidney transplant; Nitric oxide

Indexed keywords

BETA 2 MICROGLOBULIN; CD47 ANTIGEN; CLUSTERIN; CREATININE; CYSTATIN C; IMMUNOGLOBULIN; MAGNESIUM; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD47; NITRIC OXIDE; OSTEOPONTIN; OX 101; PHOSPHORUS; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UNCLASSIFIED DRUG; VASCULOTROPIN A; CD47 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; GRAFT RECIPIENT; HISTOLOGY; IMMUNOHISTOCHEMISTRY; KIDNEY BLOOD FLOW; KIDNEY INJURY; KIDNEY NECROSIS; KIDNEY TRANSPLANTATION; LASER DOPPLER FLOWMETRY; MALE; NEPHRECTOMY; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; SURVIVAL; UREA NITROGEN BLOOD LEVEL; ANIMAL; GRAFT SURVIVAL; IMMUNOLOGY; KIDNEY; LEWIS RAT; PATHOLOGY; PHYSIOLOGY; TREATMENT OUTCOME; VASCULARIZATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD47; GRAFT SURVIVAL; KIDNEY; KIDNEY TRANSPLANTATION; MALE; RATS; RATS, INBRED LEW; REPERFUSION INJURY; TREATMENT OUTCOME;

EID: 84907978568     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0000000000000252     Document Type: Article

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