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Volumn 7, Issue 1, 2014, Pages

A novel GPR40 agonist, CNX-011-67, suppresses glucagon secretion in pancreatic islets under chronic glucolipotoxic conditions in vitro

Author keywords

CNX 011 67; GCG; Glucagon; Glucolipotoxcity; GPR40

Indexed keywords

CNX-011-67; DRUG; GLUCAGON; GLUCOSE; LIPID;

EID: 84907978038     PISSN: None     EISSN: 17560500     Source Type: Journal    
DOI: 10.1186/1756-0500-7-595     Document Type: Article
Times cited : (7)

References (11)
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    • (1999) Am J Physiol , vol.277 , pp. E283-E290
    • Shah, P.1    Basu, A.2    Basu, R.3    Rizza, R.4
  • 2
    • 0029591383 scopus 로고
    • The key role of islet dysfunction in type II diabetes mellitus
    • Porte D Jr, Kahn SE: The key role of islet dysfunction in type II diabetes mellitus. Clin Invest Med 1995, 18:247-254.
    • (1995) Clin Invest Med , vol.18 , pp. 247-254
    • Porte, D.1    Kahn, S.E.2
  • 4
    • 80052576130 scopus 로고    scopus 로고
    • Acute stimulation of glucagon secretion by linoleic acid results from GPR40 activation and [Ca2+]i increase in pancreatic islet {alpha}-cells
    • Wang L, Zhao Y, Gui B, Fu R, Ma F, Yu J, Qu P, Dong L, Chen C: Acute stimulation of glucagon secretion by linoleic acid results from GPR40 activation and [Ca2+]i increase in pancreatic islet {alpha}-cells. J Endocrinol 2011, 210:173-179.
    • (2011) J Endocrinol , vol.210 , pp. 173-179
    • Wang, L.1    Zhao, Y.2    Gui, B.3    Fu, R.4    Ma, F.5    Yu, J.6    Qu, P.7    Dong, L.8    Chen, C.9
  • 8
    • 84856019616 scopus 로고    scopus 로고
    • The effects of TAK-875, a selective G protein-coupled receptor 40/free fatty acid 1 agonist, on insulin and glucagon secretion in isolated rat and human islets
    • Yashiro H, Tsujihata Y, Takeuchi K, Hazama M, Johnson PR, Rorsman P: The effects of TAK-875, a selective G protein-coupled receptor 40/free fatty acid 1 agonist, on insulin and glucagon secretion in isolated rat and human islets. J Pharmacol Exp Ther 2012, 340:483-489.
    • (2012) J Pharmacol Exp Ther , vol.340 , pp. 483-489
    • Yashiro, H.1    Tsujihata, Y.2    Takeuchi, K.3    Hazama, M.4    Johnson, P.R.5    Rorsman, P.6
  • 11
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    • Inhibition of Ca2+ signaling and glucagon secretion in mouse pancreatic alpha-cells by extracellular ATP and purinergic receptors
    • Tudurí E, Filiputti E, Carneiro EM, Quesada I: Inhibition of Ca2+ signaling and glucagon secretion in mouse pancreatic alpha-cells by extracellular ATP and purinergic receptors. Am J Physiol Endocrinol Metab 2008, 294:E952-60.
    • (2008) Am J Physiol Endocrinol Metab , vol.294 , pp. E952-E960
    • Tudurí, E.1    Filiputti, E.2    Carneiro, E.M.3    Quesada, I.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.