-
1
-
-
0032877316
-
Impact of lack of suppression of glucagon on glucose tolerance in humans
-
Shah P, Basu A, Basu R, Rizza R: Impact of lack of suppression of glucagon on glucose tolerance in humans. Am J Physiol 1999, 277:E283-E290.
-
(1999)
Am J Physiol
, vol.277
, pp. E283-E290
-
-
Shah, P.1
Basu, A.2
Basu, R.3
Rizza, R.4
-
2
-
-
0029591383
-
The key role of islet dysfunction in type II diabetes mellitus
-
Porte D Jr, Kahn SE: The key role of islet dysfunction in type II diabetes mellitus. Clin Invest Med 1995, 18:247-254.
-
(1995)
Clin Invest Med
, vol.18
, pp. 247-254
-
-
Porte, D.1
Kahn, S.E.2
-
3
-
-
84880637351
-
Treatment with CNX-011-67, a novel GPR40 agonist, delays onset and progression of diabetes and improves beta cell preservation and function in male ZDF rats
-
Gowda N, Dandu A, Singh J, Biswas S, Raghav V, Lakshmi MN, Shilpa PC, Sunil V, Reddy A, Sadasivuni M, Aparna K, Verma MK, Moolemath Y, Anup MO, Venkataranganna MV, Somesh BP, Jagannath MR: Treatment with CNX-011-67, a novel GPR40 agonist, delays onset and progression of diabetes and improves beta cell preservation and function in male ZDF rats. BMC Pharmacol Toxicol 2013, 14:28.
-
(2013)
BMC Pharmacol Toxicol
, vol.14
, pp. 28
-
-
Gowda, N.1
Dandu, A.2
Singh, J.3
Biswas, S.4
Raghav, V.5
Lakshmi, M.N.6
Shilpa, P.C.7
Sunil, V.8
Reddy, A.9
Sadasivuni, M.10
Aparna, K.11
Verma, M.K.12
Moolemath, Y.13
Anup, M.O.14
Venkataranganna, M.V.15
Somesh, B.P.16
Jagannath, M.R.17
-
4
-
-
80052576130
-
Acute stimulation of glucagon secretion by linoleic acid results from GPR40 activation and [Ca2+]i increase in pancreatic islet {alpha}-cells
-
Wang L, Zhao Y, Gui B, Fu R, Ma F, Yu J, Qu P, Dong L, Chen C: Acute stimulation of glucagon secretion by linoleic acid results from GPR40 activation and [Ca2+]i increase in pancreatic islet {alpha}-cells. J Endocrinol 2011, 210:173-179.
-
(2011)
J Endocrinol
, vol.210
, pp. 173-179
-
-
Wang, L.1
Zhao, Y.2
Gui, B.3
Fu, R.4
Ma, F.5
Yu, J.6
Qu, P.7
Dong, L.8
Chen, C.9
-
5
-
-
0021711003
-
Insulin within islets is a physiologic glucagon release inhibitor
-
Maruyama H, Hisatomi A, Orci L, Grodsky GM, Unger RH: Insulin within islets is a physiologic glucagon release inhibitor. J Clin Invest 1984, 74:2296-2299.
-
(1984)
J Clin Invest
, vol.74
, pp. 2296-2299
-
-
Maruyama, H.1
Hisatomi, A.2
Orci, L.3
Grodsky, G.M.4
Unger, R.H.5
-
6
-
-
84906922814
-
CNX-011-67, a novel GPR40 agonist, enhances glucose responsiveness, insulin secretion and islet insulin content in n-STZ rats and in islets from type 2 diabetic patients
-
Sunil V, Verma MK, Oommen AM, Sadasivuni M, Singh J, Vijayraghav DN, Chandravanshi B, Shetty J, Biswas S, Dandu A, Moolemath Y, Venkataranganna MV, Somesh BP, Jagannath MR: CNX-011-67, a novel GPR40 agonist, enhances glucose responsiveness, insulin secretion and islet insulin content in n-STZ rats and in islets from type 2 diabetic patients. BMC Pharmacol Toxicol 2014, 15:19.
-
(2014)
BMC Pharmacol Toxicol
, vol.15
, pp. 19
-
-
Sunil, V.1
Verma, M.K.2
Oommen, A.M.3
Sadasivuni, M.4
Singh, J.5
Vijayraghav, D.N.6
Chandravanshi, B.7
Shetty, J.8
Biswas, S.9
Dandu, A.10
Moolemath, Y.11
Venkataranganna, M.V.12
Somesh, B.P.13
Jagannath, M.R.14
-
7
-
-
84879495791
-
Chronic glucolipotoxic conditions in pancreatic islets impair insulin secretion due to dysregulated calcium dynamics, glucose responsiveness and mitochondrial activity
-
Somesh BP, Verma MK, Sadasivuni MK, Mammen-Oommen A, Biswas S, Shilpa PC, Reddy AK, Yateesh AN, Pallavi PM, Nethra S, Smitha R, Neelima K, Narayanan U, Jagannath MR: Chronic glucolipotoxic conditions in pancreatic islets impair insulin secretion due to dysregulated calcium dynamics, glucose responsiveness and mitochondrial activity. BMC Cell Biol 2013, 14:31.
-
(2013)
BMC Cell Biol
, vol.14
, pp. 31
-
-
Somesh, B.P.1
Verma, M.K.2
Sadasivuni, M.K.3
Mammen-Oommen, A.4
Biswas, S.5
Shilpa, P.C.6
Reddy, A.K.7
Yateesh, A.N.8
Pallavi, P.M.9
Nethra, S.10
Smitha, R.11
Neelima, K.12
Narayanan, U.13
Jagannath, M.R.14
-
8
-
-
84856019616
-
The effects of TAK-875, a selective G protein-coupled receptor 40/free fatty acid 1 agonist, on insulin and glucagon secretion in isolated rat and human islets
-
Yashiro H, Tsujihata Y, Takeuchi K, Hazama M, Johnson PR, Rorsman P: The effects of TAK-875, a selective G protein-coupled receptor 40/free fatty acid 1 agonist, on insulin and glucagon secretion in isolated rat and human islets. J Pharmacol Exp Ther 2012, 340:483-489.
-
(2012)
J Pharmacol Exp Ther
, vol.340
, pp. 483-489
-
-
Yashiro, H.1
Tsujihata, Y.2
Takeuchi, K.3
Hazama, M.4
Johnson, P.R.5
Rorsman, P.6
-
9
-
-
0037434991
-
Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40
-
Itoh Y, Kawamata Y, Harada M, Kobayashi M, Fujii R, Fukusumi S, Ogi K, Hosoya M, Tanaka Y, Uejima H, Tanaka H, Maruyama M, Satoh R, Okubo S, Kizawa H, Komatsu H, Matsumura F, Noguchi Y, Shinohara T, Hinuma S, Fujisawa Y, Fujino M: Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40. Nature 2003, 422:173-176.
-
(2003)
Nature
, vol.422
, pp. 173-176
-
-
Itoh, Y.1
Kawamata, Y.2
Harada, M.3
Kobayashi, M.4
Fujii, R.5
Fukusumi, S.6
Ogi, K.7
Hosoya, M.8
Tanaka, Y.9
Uejima, H.10
Tanaka, H.11
Maruyama, M.12
Satoh, R.13
Okubo, S.14
Kizawa, H.15
Komatsu, H.16
Matsumura, F.17
Noguchi, Y.18
Shinohara, T.19
Hinuma, S.20
Fujisawa, Y.21
Fujino, M.22
more..
-
10
-
-
77956399106
-
GLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N-and L-type Ca2+ channel-dependent exocytosis
-
De Marinis YZ, Salehi A, Ward CE, Zhang Q, Abdulkader F, Bengtsson M, Braha O, Braun M, Ramracheya R, Amisten S, Habib AM, Moritoh Y, Zhang E, Reimann F, Rosengren AH, Shibasaki T, Gribble F, Renström E, Seino S, Eliasson L, Rorsman P: GLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N-and L-type Ca2+ channel-dependent exocytosis. Cell Metab 2010, 11:543-553.
-
(2010)
Cell Metab
, vol.11
, pp. 543-553
-
-
De Marinis, Y.Z.1
Salehi, A.2
Ward, C.E.3
Zhang, Q.4
Abdulkader, F.5
Bengtsson, M.6
Braha, O.7
Braun, M.8
Ramracheya, R.9
Amisten, S.10
Habib, A.M.11
Moritoh, Y.12
Zhang, E.13
Reimann, F.14
Rosengren, A.H.15
Shibasaki, T.16
Gribble, F.17
Renström, E.18
Seino, S.19
Eliasson, L.20
Rorsman, P.21
more..
-
11
-
-
45549109667
-
Inhibition of Ca2+ signaling and glucagon secretion in mouse pancreatic alpha-cells by extracellular ATP and purinergic receptors
-
Tudurí E, Filiputti E, Carneiro EM, Quesada I: Inhibition of Ca2+ signaling and glucagon secretion in mouse pancreatic alpha-cells by extracellular ATP and purinergic receptors. Am J Physiol Endocrinol Metab 2008, 294:E952-60.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
, pp. E952-E960
-
-
Tudurí, E.1
Filiputti, E.2
Carneiro, E.M.3
Quesada, I.4
|