Differential activation of placental unfolded protein response pathways implies heterogeneity in causation of early- and late-onset pre-eclampsia

Journal of Pathology

Volumn 234, Issue 2, 2014, Pages 262-276

  Yung, Hong Wa ^a   Atkinson, Daniel ^a   Campion Smith, Tim ^b   Olovsson, Matts ^b   Charnock Jones, D Stephen ^a,c   Burton, Graham J ^a,c  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UPPSALA UNIVERSITY   (Sweden)

^c University of Cambridge ^*  (United Kingdom)

Author keywords

Cell stress responses; Growth restriction; Placenta; Pre eclampsia; Pregnancy; Unfolded protein response

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; ADENOSINE PHOSPHATE ACTIVATED PROTEIN KINASE ALPHA; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 94; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INITIATION FACTOR 2ALPHA; INTERLEUKIN 1BETA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN IRE1; PROTEIN IRE1 ALPHA; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; GLUCOSE REGULATED PROTEINS; GLUCOSE-REGULATED PROTEINS; MEMBRANE PROTEIN;

ADULT; ARTICLE; CELL HYPOXIA; CELL PROLIFERATION; CESAREAN SECTION; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; FEMALE; GESTATIONAL AGE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; PLACENTA; PREECLAMPSIA; PROTEIN PHOSPHORYLATION; REOXYGENATION; SECOND TRIMESTER PREGNANCY; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; CELL CULTURE; CELLULAR STRESS RESPONSE; GROWTH RESTRICTION; INTRAUTERINE GROWTH RETARDATION; METABOLISM; PATHOLOGY; PHYSIOLOGY; PREGNANCY;

CELL STRESS RESPONSES; GROWTH RESTRICTION; PLACENTA; PRE-ECLAMPSIA; PREGNANCY; UNFOLDED PROTEIN RESPONSE;

ADULT; CELLS, CULTURED; FEMALE; FETAL GROWTH RETARDATION; GESTATIONAL AGE; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MEMBRANE PROTEINS; PLACENTA; PRE-ECLAMPSIA; PREGNANCY; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

EID: 84907947988     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4394     Document Type: Article

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