메뉴 건너뛰기




Volumn 46, Issue 9, 2014, Pages 1047-1054

Chemotherapeutic efficacy of an ethanolic Moringa oleifera leaf extract against chromium-induced testicular toxicity in rats

Author keywords

Antioxidant; Chromium; Immunostimulant; Moringa oleifera; Sperm parameters

Indexed keywords

ALBUMIN; ALCOHOL; C REACTIVE PROTEIN; CHROMIUM; COPPER; DICHROMATE POTASSIUM; GLOBULIN; GLUTATHIONE; IMMUNOGLOBULIN A; IRON; MALONALDEHYDE; MORINGA OLEIFERA EXTRACT; TESTOSTERONE; ANTIOXIDANT; PLANT EXTRACT;

EID: 84907924627     PISSN: 03034569     EISSN: 14390272     Source Type: Journal    
DOI: 10.1111/and.12196     Document Type: Article
Times cited : (51)

References (44)
  • 1
    • 77953554147 scopus 로고    scopus 로고
    • Mineral composition of Moringa oleifera leaves pods and seeds from two regions in Abuja. Nigeria
    • Anjorin ST, Ikokoh PS, Okolo A (2010) Mineral composition of Moringa oleifera leaves pods and seeds from two regions in Abuja. Nigeria. Int J Agric Biol 12:1560-1569.
    • (2010) Int J Agric Biol , vol.12 , pp. 1560-1569
    • Anjorin, S.T.1    Ikokoh, P.S.2    Okolo, A.3
  • 2
    • 33745959003 scopus 로고    scopus 로고
    • Evaluation of antioxidant activity of some plant extracts and their heat, pH and storage stability
    • Arabshahi DS, Devi V, Urooj A (2007) Evaluation of antioxidant activity of some plant extracts and their heat, pH and storage stability. Food Chem 100:1100-1105.
    • (2007) Food Chem , vol.100 , pp. 1100-1105
    • Arabshahi, D.S.1    Devi, V.2    Urooj, A.3
  • 3
    • 34548507061 scopus 로고    scopus 로고
    • Mineral composition of Moringa oleifera leaves and pods from different regions of Punjab, Pakistan
    • Aslam MF, Anwar R, Nadeem U, Rashid TG, Kazi A, Nadeem M (2005) Mineral composition of Moringa oleifera leaves and pods from different regions of Punjab, Pakistan. Asian J Plant Sci 4:417-421.
    • (2005) Asian J Plant Sci , vol.4 , pp. 417-421
    • Aslam, M.F.1    Anwar, R.2    Nadeem, U.3    Rashid, T.G.4    Kazi, A.5    Nadeem, M.6
  • 4
    • 0025859117 scopus 로고
    • Diagnosis of a testosterone-secreting adrenal adenoma by selective venous catheterization
    • Chen A, Bookstein JJ, Meldrum DR (1991) Diagnosis of a testosterone-secreting adrenal adenoma by selective venous catheterization. Fertil Steril 55:1202-1203.
    • (1991) Fertil Steril , vol.55 , pp. 1202-1203
    • Chen, A.1    Bookstein, J.J.2    Meldrum, D.R.3
  • 6
    • 33750490414 scopus 로고    scopus 로고
    • Antioxidant effects of black rice extract through the induction of superoxide dismutase and catalase activities
    • Chiang AN, Wu HL, Yen HI (2006) Antioxidant effects of black rice extract through the induction of superoxide dismutase and catalase activities. Lipids 41:797-803.
    • (2006) Lipids , vol.41 , pp. 797-803
    • Chiang, A.N.1    Wu, H.L.2    Yen, H.I.3
  • 7
    • 0017151033 scopus 로고
    • Purification and properties of rat lung soluble glutathione peroxidase
    • Chiu D, Fredrick H, Tappel AL (1976) Purification and properties of rat lung soluble glutathione peroxidase. Biochim Biophys Acta 445:558-566.
    • (1976) Biochim Biophys Acta , vol.445 , pp. 558-566
    • Chiu, D.1    Fredrick, H.2    Tappel, A.L.3
  • 8
    • 0004264746 scopus 로고
    • 1st edn. W. B Saunders Co. Philadelphia, London, Toronto
    • Coles EH (1974) Veterinary Clinical Pathology, 1st edn. W. B Saunders Co. Philadelphia, London, Toronto, pp 212-213.
    • (1974) Veterinary Clinical Pathology , pp. 212-213
    • Coles, E.H.1
  • 9
    • 84875452456 scopus 로고    scopus 로고
    • Effect of ethanolic extract of leaves of moringa olifera lam. On acetic acid induced colitis in albino rats
    • Das S, Kanodia L (2012) Effect of ethanolic extract of leaves of moringa olifera lam. On acetic acid induced colitis in albino rats. Asian J Pharm Clin Res 5:110-114.
    • (2012) Asian J Pharm Clin Res , vol.5 , pp. 110-114
    • Das, S.1    Kanodia, L.2
  • 10
    • 29244436102 scopus 로고    scopus 로고
    • Effect of piperine on the epididymis of adult male rats
    • D'cruz M (2005) Effect of piperine on the epididymis of adult male rats. Asian J Androl 7:363-368.
    • (2005) Asian J Androl , vol.7 , pp. 363-368
    • D'cruz, M.1
  • 11
    • 0024424383 scopus 로고
    • Mechanism of chromium (VI) metabolism and genotoxicity
    • DeFlora S, Wetterhahn KE (1989) Mechanism of chromium (VI) metabolism and genotoxicity. Life Chem Rep 7:169-244.
    • (1989) Life Chem Rep , vol.7 , pp. 169-244
    • DeFlora, S.1    Wetterhahn, K.E.2
  • 12
    • 84881489327 scopus 로고    scopus 로고
    • Effect of chromium on certain aspects of cellular toxicity
    • Dey SK, Roy S (2009) Effect of chromium on certain aspects of cellular toxicity. Iranian J Toxicol 2:260-267.
    • (2009) Iranian J Toxicol , vol.2 , pp. 260-267
    • Dey, S.K.1    Roy, S.2
  • 15
    • 84902296438 scopus 로고
    • Latex serology test for detection of C-Reactive protein
    • Fisher CL, Nakamura R (1976) Latex serology test for detection of C-Reactive protein. Am J Clin Pathol 66:840-847.
    • (1976) Am J Clin Pathol , vol.66 , pp. 840-847
    • Fisher, C.L.1    Nakamura, R.2
  • 16
    • 0016275313 scopus 로고
    • Glutathione S-transferase: the first enzymatic step in mercapturic acid formation
    • Habig WH, Pabst MI, Jakoby WB (1974) Glutathione S-transferase: the first enzymatic step in mercapturic acid formation. J Biol Chem 249:1730-1739.
    • (1974) J Biol Chem , vol.249 , pp. 1730-1739
    • Habig, W.H.1    Pabst, M.I.2    Jakoby, W.B.3
  • 17
    • 0036774226 scopus 로고    scopus 로고
    • Flavonoid antioxidants: chemistry, metabolism and structure activity relationships
    • Heim KE, Tagliaferro AR, Bobilya DJ (2002) Flavonoid antioxidants: chemistry, metabolism and structure activity relationships. J Nutr Biochem 13:572-584.
    • (2002) J Nutr Biochem , vol.13 , pp. 572-584
    • Heim, K.E.1    Tagliaferro, A.R.2    Bobilya, D.J.3
  • 19
    • 33744935270 scopus 로고    scopus 로고
    • Effect of season and production location on antioxidant activity of Moringa oleifera leaves grown in Pakistan
    • Iqbal S, Bhanger M (2006) Effect of season and production location on antioxidant activity of Moringa oleifera leaves grown in Pakistan. J Food Compost Anal 19:544-551.
    • (2006) J Food Compost Anal , vol.19 , pp. 544-551
    • Iqbal, S.1    Bhanger, M.2
  • 21
    • 0035008460 scopus 로고    scopus 로고
    • Colorimetric method for determination of total antioxidant capacity
    • Koracevic D, Koracevic G (2001) Colorimetric method for determination of total antioxidant capacity. J Clin Pathol 54:356-361.
    • (2001) J Clin Pathol , vol.54 , pp. 356-361
    • Koracevic, D.1    Koracevic, G.2
  • 22
    • 8544224992 scopus 로고    scopus 로고
    • Metal-induced oxidative stress and signal transduction
    • Leonard SS, Harris GK, Shi XL (2004) Metal-induced oxidative stress and signal transduction. Free Radic Biol Med 37:1921-1942.
    • (2004) Free Radic Biol Med , vol.37 , pp. 1921-1942
    • Leonard, S.S.1    Harris, G.K.2    Shi, X.L.3
  • 23
    • 84858962473 scopus 로고    scopus 로고
    • Antioxidant and free radical scavenging activity of Hygrophila schulli (Buch.-Ham.) Almeida and Almeida seeds
    • Lobo VC, Phatak A, Chandra N (2010) Antioxidant and free radical scavenging activity of Hygrophila schulli (Buch.-Ham.) Almeida and Almeida seeds. Adv Biores 1:72-78.
    • (2010) Adv Biores , vol.1 , pp. 72-78
    • Lobo, V.C.1    Phatak, A.2    Chandra, N.3
  • 25
    • 73549092718 scopus 로고    scopus 로고
    • Inhibitory effect of n-butanol fraction of Moringa oleifera Lam. Seeds on ovalbumin-induced airway inflammation in a guinea pig model of asthma
    • Mahajan SG, Banerjee A, Chauhan BF, Padh H, Nivsarkar M, Mehta AA (2009) Inhibitory effect of n-butanol fraction of Moringa oleifera Lam. Seeds on ovalbumin-induced airway inflammation in a guinea pig model of asthma. Int J Toxicol 28:519-527.
    • (2009) Int J Toxicol , vol.28 , pp. 519-527
    • Mahajan, S.G.1    Banerjee, A.2    Chauhan, B.F.3    Padh, H.4    Nivsarkar, M.5    Mehta, A.A.6
  • 26
    • 0015523099 scopus 로고
    • The role of superoxide anion in the auto-oxidation of epinephrine and a simple assay for superoxide dismutase
    • Misra HP, Fridovich I (1972) The role of superoxide anion in the auto-oxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem 247:3170-3175.
    • (1972) J Biol Chem , vol.247 , pp. 3170-3175
    • Misra, H.P.1    Fridovich, I.2
  • 27
    • 84861940125 scopus 로고    scopus 로고
    • Moringa oleifera leaf extract prevent early liver injury and restores antioxidant status in mice fed with high fat diet
    • Nilanjan D, Kunal S, Santinath G, Bernard F, Sanjit D (2012) Moringa oleifera leaf extract prevent early liver injury and restores antioxidant status in mice fed with high fat diet. Indian J Exp Biol 50:404-412.
    • (2012) Indian J Exp Biol , vol.50 , pp. 404-412
    • Nilanjan, D.1    Kunal, S.2    Santinath, G.3    Bernard, F.4    Sanjit, D.5
  • 29
    • 67650649810 scopus 로고    scopus 로고
    • Antioxidative properties of ethyl acetate fraction of Globimetula branuii in normal rats
    • Okpuzor J, Ogbunugafor H, Kareem GK (2009) Antioxidative properties of ethyl acetate fraction of Globimetula branuii in normal rats. J Biol Sci 9:470-475.
    • (2009) J Biol Sci , vol.9 , pp. 470-475
    • Okpuzor, J.1    Ogbunugafor, H.2    Kareem, G.K.3
  • 30
    • 84876240943 scopus 로고    scopus 로고
    • Comparison of antioxidant activity of Moringa oleifera and selected vegetables in South Africa
    • Pakade V, Cukrowska E, Chimuka L (2013) Comparison of antioxidant activity of Moringa oleifera and selected vegetables in South Africa. S Afr J Sci 109:1-5.
    • (2013) S Afr J Sci , vol.109 , pp. 1-5
    • Pakade, V.1    Cukrowska, E.2    Chimuka, L.3
  • 31
    • 0014375629 scopus 로고
    • Proposals for standardization of total protein assays
    • Peters TJ (1968) Proposals for standardization of total protein assays. Clin Chem 14:1147.
    • (1968) Clin Chem , vol.14 , pp. 1147
    • Peters, T.J.1
  • 32
    • 0013937181 scopus 로고
    • Estimation of product of lipid peroxidation (malondialdehyde) in biochemical system
    • Placer ZA, Crushman L, Son BC (1966) Estimation of product of lipid peroxidation (malondialdehyde) in biochemical system. Anal Biochem 16:359-364.
    • (1966) Anal Biochem , vol.16 , pp. 359-364
    • Placer, Z.A.1    Crushman, L.2    Son, B.C.3
  • 33
    • 33745034571 scopus 로고    scopus 로고
    • Antioxidant activity, phenol and flavonoids content of some selected Iranian plants
    • Pourmorad F, Hosseinimehr SJ, Shahabimajd N (2006) Antioxidant activity, phenol and flavonoids content of some selected Iranian plants. Afr J Biotechnol 5:1142-1145.
    • (2006) Afr J Biotechnol , vol.5 , pp. 1142-1145
    • Pourmorad, F.1    Hosseinimehr, S.J.2    Shahabimajd, N.3
  • 34
    • 84868144099 scopus 로고    scopus 로고
    • In vivo antioxidant activity of Moringa oleifera leaf and pod extracts against carbon tetra chloride induced liver damage in albino mice
    • Rakesh S, Singh VJ (2010) In vivo antioxidant activity of Moringa oleifera leaf and pod extracts against carbon tetra chloride induced liver damage in albino mice. J Chem Pharm Res 2:275-283.
    • (2010) J Chem Pharm Res , vol.2 , pp. 275-283
    • Rakesh, S.1    Singh, V.J.2
  • 35
    • 34347336995 scopus 로고    scopus 로고
    • An evaluation of the deleterious effect of unilateral cryptorchidism on the contralateral normally descended testis
    • Saalu LC, Adesanya AO, Oyewopo AO, Raji Y (2007) An evaluation of the deleterious effect of unilateral cryptorchidism on the contralateral normally descended testis. Sci Res Essays 2:74-78.
    • (2007) Sci Res Essays , vol.2 , pp. 74-78
    • Saalu, L.C.1    Adesanya, A.O.2    Oyewopo, A.O.3    Raji, Y.4
  • 36
    • 80051915994 scopus 로고    scopus 로고
    • Moringa oleifera Lamarck (drumstick) leaf extract modulates the evidences of hydroxyurea-induced testicular derangement
    • Saalu LC, Osinubi AA, Akinbami AA, Yama OE, Oyewopo AO, Enaibe BU (2011) Moringa oleifera Lamarck (drumstick) leaf extract modulates the evidences of hydroxyurea-induced testicular derangement. Int J Appl Res Nat Prod 4:32-45.
    • (2011) Int J Appl Res Nat Prod , vol.4 , pp. 32-45
    • Saalu, L.C.1    Osinubi, A.A.2    Akinbami, A.A.3    Yama, O.E.4    Oyewopo, A.O.5    Enaibe, B.U.6
  • 38
    • 33645122590 scopus 로고
    • Estimation of total protein bound and non protein sulfhydryl groups in tissues with Ellman reagent
    • Sedlack J, Lindsay RH (1968) Estimation of total protein bound and non protein sulfhydryl groups in tissues with Ellman reagent. Anal Biochem 86:271-278.
    • (1968) Anal Biochem , vol.86 , pp. 271-278
    • Sedlack, J.1    Lindsay, R.H.2
  • 39
    • 0037427309 scopus 로고    scopus 로고
    • Antioxidant properties of various solvent extracts of total phenolic constituents from three different agroclimatic origins of drumstick tree (Moringa oleifera Lam) leaves
    • Siddhuraju P, Becker K (2003) Antioxidant properties of various solvent extracts of total phenolic constituents from three different agroclimatic origins of drumstick tree (Moringa oleifera Lam) leaves. J Agric Food Chem 51:2144-2155.
    • (2003) J Agric Food Chem , vol.51 , pp. 2144-2155
    • Siddhuraju, P.1    Becker, K.2
  • 40
    • 0015353270 scopus 로고
    • Calorimetric assay of catalase
    • Sinha KA (1971) Calorimetric assay of catalase. Anal Biochem 47:389-394.
    • (1971) Anal Biochem , vol.47 , pp. 389-394
    • Sinha, K.A.1
  • 42
    • 71449112883 scopus 로고    scopus 로고
    • Antioxidant activity and total phenolic content in Moringa oleifera leaves in two stages of maturity
    • Sreelatha S, Padma PR (2010) Antioxidant activity and total phenolic content in Moringa oleifera leaves in two stages of maturity. Plant Foods Hum Nutr 64:303-311.
    • (2010) Plant Foods Hum Nutr , vol.64 , pp. 303-311
    • Sreelatha, S.1    Padma, P.R.2
  • 43
    • 0028798434 scopus 로고
    • Oxidative mechanisms in the toxicity of metal ions
    • Stohs SJ, Bagchi D (1995) Oxidative mechanisms in the toxicity of metal ions. Free Radic Biol Med 18:321-336.
    • (1995) Free Radic Biol Med , vol.18 , pp. 321-336
    • Stohs, S.J.1    Bagchi, D.2
  • 44
    • 0026515041 scopus 로고
    • Role of physiological antioxidant in chromium (VI)-induced cellular injury
    • Sugiyama M (1992) Role of physiological antioxidant in chromium (VI)-induced cellular injury. Free Radic Biol Med 12:397-407.
    • (1992) Free Radic Biol Med , vol.12 , pp. 397-407
    • Sugiyama, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.