Type X collagen levels are elevated in serum from human osteoarthritis patients and associated with biomarkers of cartilage degradation and inflammation

BMC Musculoskeletal Disorders

Volumn 15, Issue 1, 2014, Pages

  He, Yi ^a   Siebuhr, Anne Sofie ^a   Brandt Hansen, Niels Ulrik ^a   Wang, Jianxia ^b   Su, Di ^b   Zheng, Qinlong ^b   Simonsen, Ole ^c   Petersen, Kristian Kjær ^c,d   Arendt Nielsen, Lars ^d   Eskehave, Thomas ^e   Hoeck, Hans Christian ^e   Karsdal, Morten Asser ^a   Bay Jensen, Anne C ^a  

^a NORDIC BIOSCIENCE A S   (Denmark)

^b Zhongguancun Life Science Park   (China)

^c AALBORG UNIVERSITY HOSPITAL   (Denmark)

^d AALBORG UNIVERSITY   (Denmark)

^e Center for Clinicl and Basic Research and C4Pain   (Denmark)

Author keywords

Biomarkers; Cartilage degradation; Hypertrophic chondrocytes; Inflammation; Osteoarthritis; Type II collagen; Type X collagen

Indexed keywords

C REACTIVE PROTEIN; COLLAGEN TYPE 10; COLLAGEN TYPE 2; MATRIX METALLOPROTEINASE; MONOCLONAL ANTIBODY; BIOLOGICAL MARKER;

ADULT; AGED; ANTIBODY SPECIFICITY; ARTICLE; CARTILAGE; CARTILAGE BIOPSY; CARTILAGE CELL; CARTILAGE DEGENERATION; CARTILAGE MATRIX; CELL LYSATE; CHONDROCYTE HYPERTROPHY; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME DEGRADATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HYPERTROPHY; IC50; IMMUNOASSAY; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; IMMUNOREACTIVITY; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; OSTEOARTHRITIS; PROTEIN BLOOD LEVEL; SEQUENCE ALIGNMENT; WESTERN BLOTTING; BLOOD; CARTILAGE DISEASES; COHORT ANALYSIS; OSTEOARTHRITIS, KNEE; TUMOR CELL LINE;

BIOLOGICAL MARKERS; CARTILAGE DISEASES; CELL LINE, TUMOR; COHORT STUDIES; COLLAGEN TYPE X; FEMALE; HUMANS; INFLAMMATION; MALE; OSTEOARTHRITIS, KNEE;

EID: 84907914365     PISSN: None     EISSN: 14712474     Source Type: Journal    
DOI: 10.1186/1471-2474-15-309     Document Type: Article

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