Dexamethasone intravitreous implant versus bevacizumab for central retinal vein occlusion-related macular oedema: A prospective randomized comparison

Clinical and Experimental Ophthalmology

Volumn 42, Issue 7, 2014, Pages 650-655

  Gado, Ahmed S ^a   Macky, Tamer A ^a  

^a Cairo University   (Egypt)

Author keywords

Central retinal vein occlusion; Dexamethasone implant (Ozurdex); Intravitreal bevacizumab (Avastin); Macular oedema

Indexed keywords

BEVACIZUMAB; DEXAMETHASONE; ANGIOGENESIS INHIBITOR; DRUG IMPLANT; GLUCOCORTICOID; MONOCLONAL ANTIBODY; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

AGED; ARTICLE; CENTRAL CORNEAL THICKNESS; CENTRAL RETINA VEIN OCCLUSION; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; FLUORESCENCE ANGIOGRAPHY; FOLLOW UP; HUMAN; INTRAOCULAR PRESSURE; MACULAR EDEMA; MAJOR CLINICAL STUDY; MALE; OPTICAL COHERENCE TOMOGRAPHY; OUTCOME ASSESSMENT; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SLIT LAMP; TREATMENT DURATION; UNIVERSITY HOSPITAL; UNSPECIFIED SIDE EFFECT; VISUAL ACUITY; ADULT; ANTAGONISTS AND INHIBITORS; COMPARATIVE STUDY; COMPLICATION; DRUG EFFECTS; DRUG IMPLANT; INTRAVITREAL DRUG ADMINISTRATION; MIDDLE AGED; RETINAL VEIN OCCLUSION; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANGIOGENESIS INHIBITORS; ANTIBODIES, MONOCLONAL, HUMANIZED; DEXAMETHASONE; DRUG IMPLANTS; FEMALE; FLUORESCEIN ANGIOGRAPHY; GLUCOCORTICOIDS; HUMANS; INTRAOCULAR PRESSURE; INTRAVITREAL INJECTIONS; MACULAR EDEMA; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RETINAL VEIN OCCLUSION; TOMOGRAPHY, OPTICAL COHERENCE; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VISUAL ACUITY;

EID: 84907906125     PISSN: 14426404     EISSN: 14429071     Source Type: Journal    
DOI: 10.1111/ceo.12311     Document Type: Article

References (13)

1. Hayreh SS, Zimmerman MB, Podhajsky P. Incidence of various types of retinal vein occlusion and their recurrence and demographic characteristics. Am J Ophthalmol 1994; 117: 429-441.
2. Wong TY, Larsen EK, Klein R etal. Cardiovascular risk factors for retinal vein occlusion and arteriolar emboli: the Atherosclerosis Risk in Communities & Cardiovascular Health studies. Ophthalmology 2005; 112: 540-547.
3. The Central Retinal Vein Occlusion Group. Evaluation of grid pattern photocoagulation for macular edema in central vein occlusion: the Central Vein Occlusion Study Group M report. Ophthalmology 1995; 102: 1425-1433.
4. The Central Retinal Vein Occlusion Group. A randomized clinical trial of early panretinal photocoagulation for ischemic central vein occlusion: the Central Vein Occlusion Study Group N report. Ophthalmology 1995; 102: 1434-1444.
5. Ip MS, Scott IU, VanVeldhuisen PC etal. A randomized trial comparing the efficacy and safety of intravitreal triamcinolone with observation to treat vision loss associated with macular edema secondary to central retinal vein occlusion: the Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) study report 5. Arch Ophthalmol 2009; 127: 1101-1114.
6. Haller JA, Bandello F, Belfort R etal. Randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with macular edema due to retinal vein occlusion. Ophthalmology 2010; 117: 1134-1146.
7. Boyd SR, Zachary I, Chakravarthy U etal. Correlation of increased vascular endothelial growth factor with neovascularization and permeability in ischemic central vein occlusion. Arch Ophthalmol 2002; 120: 1644-1650.
8. Brown DM, Campochiaro PA, Singh RP etal.; CRUISE Investigators. Ranibizumab for macular edema following central retinal vein occlusion: six-month primary end point results of a phase III study. Ophthalmology 2010; 117: 1124-1133.
9. Algvere PV, Epstein D, von Wendt G, Seregard S, Kvanta A. Intravitreal bevacizumab in central retinal vein occlusion: 18-month results of a prospective clinical trial. Eur J Ophthalmol 2011; 21: 789-795.
10. Prager F, Michels S, Kriechbaum K. Intravitreal bevacizumab (Avastin) for macular oedema secondary to retinal vein occlusion: 12-month results of a prospective clinical trial. Br J Ophthalmol 2009; 93: 452-456.
11. Figueroa MS, Contreras I, Noval S, Arruabarrena C. Results of bevacizumab as the primary treatment for retinal vein occlusions. Br J Ophthalmol 2010; 94: 1052-1056.
12. Opremcak EM, Bruce RA, Lomeo MD, Ridenour CD, Letson AD, Rehmar AJ. Radial optic neurotomy for central retinal vein occlusion: a retrospective pilot study of 11 consecutive cases. Retina 2001; 21: 408-415.
13. Aggermann T, Brunner S, Krebs I etal.; ROVO Study Group. A prospective, randomised, multicenter trial for surgical treatment of central retinal vein occlusion: results of the Radial Optic Neurotomy for Central Vein Occlusion (ROVO) study group. Graefes Arch Clin Exp Ophthalmol 2013; 251: 1065-1072.