Engineering ribosomal leaky scanning and upstream open reading frames for precise control of protein translation

Bioengineered

Volumn 5, Issue 3, 2014, Pages 186-192

  Ferreira, Joshua P ^a   Noderer, William L ^a   Diaz De Arce, Alexander J ^a   Wang, Clifford L ^a  

^a Stanford University   (United States)

Author keywords

Cellular stress; Posttranscriptional regulation; Ribosome scanning; Translation initiation; UORF; Upstream open reading frames

Indexed keywords

CELL STRESS; OPEN READING FRAME; PROTEIN PROCESSING; TRANSLATION INITIATION; ANIMAL; BIOSYNTHESIS; CELL LINE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; GENETICS; HAMSTER; HUMAN; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROCEDURES; PROMOTER REGION; REPORTER GENE; RIBOSOME; RNA TRANSLATION;

ACTIVATING TRANSCRIPTION FACTOR 4; ATF4 PROTEIN, HUMAN; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; MESSENGER RNA; PROTEIN P21; TRIMETHOPRIM;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; BASE SEQUENCE; CELL LINE; CRICETINAE; GENE EXPRESSION REGULATION; GENES, REPORTER; GENETIC ENGINEERING; GREEN FLUORESCENT PROTEINS; HUMANS; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS P21(RAS); RECOMBINANT FUSION PROTEINS; RIBOSOMES; RNA, MESSENGER; TRIMETHOPRIM;

EID: 84907895340     PISSN: 21655979     EISSN: 21655987     Source Type: Journal    
DOI: 10.4161/bioe.27607     Document Type: Article

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