Application of ethylcellulose coating to hydrophilic matrices: A strategy to modulate drug release profile and reduce drug release variability

AAPS PharmSciTech

Volumn 15, Issue 5, 2014, Pages 1049-1059

  Mehta, Raxit Y ^a   Missaghi, Shahrzad ^a   Tiwari, Sandip B ^a   Rajabi Siahboomi, Ali R ^a  

^a Colorcon Inc ^*  (United States)

Author keywords

bio relevant media; drug release variability; ethylcellulose coating; hydrophilic matrix tablets; hypromellose

Indexed keywords

ETHYL CELLULOSE; HYDROCHLOROTHIAZIDE; HYDROXYPROPYLMETHYLCELLULOSE; LACTOSE; POLYMER; STARCH; CELLULOSE; DIURETIC AGENT; ENTERIC COATED TABLET; EXCIPIENT;

ARTICLE; CONTROLLED STUDY; DRUG COATING; DRUG ELIMINATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STORAGE; FILM COATING; HYDRATION; HYDROPHILICITY; HYDROSTATIC PRESSURE; MAIZE; MATRIX TABLET; PHARMACOLOGICAL PARAMETERS; TABLET FORMULATION; TABLET SURFACE; ZERO ORDER RELEASE KINETIC; ANALOGS AND DERIVATIVES; CHEMISTRY; DRUG STABILITY; ENTERIC COATED TABLET; MEDICINAL CHEMISTRY; PROCEDURES;

CELLULOSE; CHEMISTRY, PHARMACEUTICAL; DIURETICS; DRUG LIBERATION; DRUG STABILITY; DRUG STORAGE; EXCIPIENTS; HYDROCHLOROTHIAZIDE; TABLETS, ENTERIC-COATED;

EID: 84907876365     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-014-0128-5     Document Type: Article

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