In vitro and in vivo erosion of two different hydrophilic gel matrix tablets

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 46, Issue 1, 1998, Pages 69-75

  Abrahamsson, Bertil ^a   Alpsten, Magne ^b   Bake, Björn ^b   Larsson, Annhild ^b   Sjögren, John ^a  

^a ASTRAZENECA R AND D   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Gamma scintigraphy; Hydrophilic matrix tablets; In vitro in vivo correlation; Tablet erosion

Indexed keywords

CARBOMER; ETHYL CELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; NIFEDIPINE; SODIUM CHLORIDE;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; GAMMA SCINTIGRAPHY; GASTROINTESTINAL TRANSIT; GEL; HUMAN; HUMAN EXPERIMENT; IONIC STRENGTH; MATRIX TABLET; MECHANICAL STRESS; MODEL; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; STOMACH EMPTYING; TABLET DISINTEGRATION;

ADULT; CHEMISTRY, PHARMACEUTICAL; DIGESTIVE SYSTEM; HUMANS; HYDROGELS; MALE; METHYLCELLULOSE; RADIONUCLIDE IMAGING; TABLETS;

EID: 0032424398     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(98)00002-2     Document Type: Article

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