Novel dexamethasone-loaded nanomicelles for the intermediate and posterior segment uveitis

AAPS PharmSciTech

Volumn 15, Issue 5, 2014, Pages 1238-1251

  Vaishya, Ravi D ^a   Gokulgandhi, Mitan ^a   Patel, Sulabh ^a   Minocha, Mukul ^b   Mitra, Ashim K ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

Author keywords

design of experiment; dexamethasone; nanomicelles; ocular drug delivery; quality by design; response surface design; uveitis

Indexed keywords

DEXAMETHASONE; POLYMER; ANTIINFLAMMATORY AGENT; MICELLE; NANOPARTICLE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CRITICAL MICELLE CONCENTRATION; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG SOLUBILITY; DRUG SYNTHESIS; EX VIVO STUDY; EXPERIMENTAL RABBIT; IN VITRO STUDY; MALE; MICELLE; MICELLIZATION; MOLECULAR WEIGHT; NANOMICELLE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RESPONSE SURFACE METHOD; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SURFACE PROPERTY; ANIMAL; CELL SURVIVAL; CONJUNCTIVA; CYTOLOGY; DRUG EFFECTS; EPITHELIUM CELL; HUMAN; METABOLISM; RABBIT; SCLERA; SOLUBILITY; UVEITIS, INTERMEDIATE; UVEITIS, POSTERIOR;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL SURVIVAL; CONJUNCTIVA; DEXAMETHASONE; EPITHELIAL CELLS; HUMANS; IN VITRO TECHNIQUES; MICELLES; NANOPARTICLES; RABBITS; SCLERA; SOLUBILITY; UVEITIS, INTERMEDIATE; UVEITIS, POSTERIOR;

EID: 84907874527     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-014-0100-4     Document Type: Article

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