Transfusion threshold of 7 g per deciliter - The new normal

New England Journal of Medicine

Volumn 371, Issue 15, 2014, Pages 1459-1461

  Hébert, Paul C ^a   Carson, Jeffrey L ^b  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^b ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN;

ACUTE CORONARY SYNDROME; BLOOD TRANSFUSION; CLINICAL PROTOCOL; CRITICALLY ILL PATIENT; DISEASE PREDISPOSITION; DISEASE SEVERITY; EDITORIAL; EVIDENCE BASED MEDICINE; GASTROINTESTINAL HEMORRHAGE; HEART MUSCLE ISCHEMIA; HEART MUSCLE OXYGEN CONSUMPTION; HEART SURGERY; HEMATOLOGICAL PARAMETERS; HEMOGLOBIN DETERMINATION; HUMAN; HYPOXEMIA; INTENSIVE CARE; ISCHEMIC HEART DISEASE; LUNG EDEMA; MORTALITY; PATIENT SAFETY; PERIOPERATIVE PERIOD; PRACTICE GUIDELINE; REFERENCE VALUE; RESUSCITATION; SEPTIC SHOCK; SYSTEMIC DISEASE; VENOUS OXYGEN TENSION; ERYTHROCYTE TRANSFUSION; FEMALE; MALE; NOTE;

ERYTHROCYTE TRANSFUSION; FEMALE; HEMOGLOBINS; HUMANS; MALE; SHOCK, SEPTIC;

EID: 84907868241     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMe1408976     Document Type: Editorial

References (18)

1. Holst LB, Haase N, Wetterslev J, et al. Lower versus higher hemoglobin threshold for transfusion in septic shock. N Engl J Med 2014;371:1381-91.
2. Hébert PC, Wells G, Blajchman MA, et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med 1999;340:409-17.
3. Hébert PC, Wells G, Blajchman MA, et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med 1999;340:1056.
4. Carson JL, Carless PA, Hebert PC. Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion. Cochrane Database Syst Rev 2012;4:CD002042.
5. Lacroix J, Hébert PC, Hutchison JS, et al. Transfusion strategies for patients in pediatric intensive care units. N Engl J Med 2007;356:1609-19.
6. Walsh TS, Boyd JA, Watson D, et al. Restrictive versus liberal transfusion strategies for older mechanically ventilated critically ill patients: A randomized pilot trial. Crit Care Med 2013;41:2354- 63.
7. Robertson CS, Hannay HJ, Yamal JM, et al. Effect of erythropoietin and transfusion threshold on neurological recovery after traumatic brain injury: A randomized clinical trial. JAMA 2014; 312:36-47.
8. The ProCESS Investigators. A randomized trial of protocolbased care for early septic shock. N Engl J Med 2014;370:1683- 93.
9. The ARISE Investigators and the ANZICS Clinical Trials Group. Goal-directed resuscitation for patients with early septic shock. N Engl J Med. DOI: 10.1056/NEJMoa1404380.
10. Rivers E, Nguyen B, Havstad S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001;345:1368-77.
11. Villanueva C, Colomo A, Bosch A, et al. Transfusion strategies for acute upper gastrointestinal bleeding. N Engl J Med 2013; 368:11-21.
12. Villanueva C, Colomo A, Bosch A, et al. Transfusion strategies for acute upper gastrointestinal bleeding, N Engl J Med 2013;368:2341.
13. Napolitano LM, Kurek S, Luchette FA, et al. Clinical practice guideline: red blood cell transfusion in adult trauma and critical care. Crit Care Med 2009;37:3124-57.
14. Napolitano LM, Kurek S, Luchette FA, et al. Clinical practice guideline: red blood cell transfusion in adult trauma and critical care, Crit Care Med 2010;38:1621.
15. Carson JL, Grossman BJ, Kleinman S, et al. Red blood cell transfusion: A clinical practice guideline from the AABB. Ann Intern Med 2012;157:49-58.
16. Retter A, Wyncoll D, Pearse R, et al. Guidelines on the management of anaemia and red cell transfusion in adult critically ill patients. Br J Haematol 2013;160:445-64.
17. Patient blood management guidelines. Canberra, ACT, Australia: National Blood Authority Australia, 2012 (http://www.blood.gov.au/pbm-guidelines).
18. Surviving Sepsis Campaign (http://www.survivingsepsis.org/Guidelines/Pages/default.aspx).