Unravelling the cross-talk between iron starvation and oxidative stress responses highlights the key role of PerR (alr0957) in peroxide signalling in the cyanobacterium NostocPCC 7120

Environmental Microbiology Reports

Volumn 6, Issue 5, 2014, Pages 468-475

  Yingping, Fan ^a   Lemeille, Sylvain ^b   Talla, Emmanuel ^a   Janicki, Annick ^a   Denis, Yann ^c   Zhang, Cheng Cai ^a   Latifi, Amel ^a  

^a AIX MARSEILLE UNIVERSITÉ   (France)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^c CNRS and Aix Marseille University   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; IRON; PEROXIDE; REPRESSOR PROTEIN;

GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NOSTOC; OXIDATIVE STRESS;

BACTERIAL PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; IRON; NOSTOC; OXIDATIVE STRESS; PEROXIDES; REPRESSOR PROTEINS;

EID: 84907861824     PISSN: None     EISSN: 17582229     Source Type: Journal    
DOI: 10.1111/1758-2229.12157     Document Type: Article

References (30)

1. Allahverdiyeva, Y., Mustila, H., Ermakova, M., Bersanini, L., Richaud, P., Ajlani, G., etal. (2013) Flavodiiron proteins Flv1 and Flv3 enable cyanobacterial growth and photosynthesis under fluctuating light. Proc Natl Acad Sci USA 110: 4111-4116.
2. Boileau, C., Eme, L., Brochier-Armanet, C., Janicki, A., Zhang, C.C., and Latifi, A. (2011) A eukaryotic-like sulfiredoxin involved in oxidative stress responses and in the reduction of the sulfinic form of 2-Cys peroxiredoxin in the cyanobacterium Anabaena PCC 7120. New Phytol 191: 1108-1118.
3. Bsat, N., Herbig, A., Casillas-Martinez, L., Setlow, P., and Helmann, J.D. (1998) Bacillus subtilis contains multiple Fur homologues: identification of the iron uptake (Fur) and peroxide regulon (PerR) repressors. Mol Microbiol 29: 189-198.
4. Dubbs, J.M., and Mongkolsuk, S. (2012) Peroxide-sensing transcriptional regulators in bacteria. J Bacteriol 194: 5495-5503.
5. Dufour, P.S., Sarazin, G., Quiblier, C., Sane, S., and Leboulanger, C. (2006) Cascading nutrient limitation of the cyanobacterium Cylindrospermopsis raciborskii in a Sahelian lake (North Senegal). Aquat Microb Ecol 44: 219-230.
6. Ermakova, M., Battchikova, N., Allahverdiyeva, Y., and Aro, E.M. (2013) Novel heterocyst-specific flavodiiron proteins in Anabaena sp. PCC 7120. FEBS Lett 587: 82-87.
7. Fitzgerald, M.P., Husain, A., Hutber, G.N., and Rogers, L.J. (1977) Studies on the flavodoxins from a cyanobacterium and a red alga [proceedings]. Biochem Soc Trans 5: 1505-1506.
8. Gonzalez, A., Bes, M.T., Barja, F., Peleato, M.L., and Fillat, M.F. (2010) Overexpression of FurA in Anabaena sp. PCC 7120 reveals new targets for this regulator involved in photosynthesis, iron uptake and cellular morphology. Plant Cell Physiol 51: 1900-1914.
9. Gonzalez, A., Bes, M.T., Peleato, M.L., and Fillat, M.F. (2011) Unravelling the regulatory function of FurA in Anabaena sp. PCC 7120 through 2-D DIGE proteomic analysis. J Proteomics 74: 660-671.
10. Gonzalez, A., Bes, M.T., Valladares, A., Peleato, M.L., and Fillat, M.F. (2012) FurA is the master regulator of iron homeostasis and modulates the expression of tetrapyrrole biosynthesis genes in Anabaena sp. PCC 7120. Environ Microbiol 14: 3175-3187.
11. Helman, Y., Tchernov, D., Reinhold, L., Shibata, M., Ogawa, T., Schwarz, R., etal. (2003) Genes encoding A-type flavoproteins are essential for photoreduction of O2 in cyanobacteria. Curr Biol 13: 230-235.
12. Houot, L., Floutier, M., Marteyn, B., Michaut, M., Picciocchi, A., Legrain, P., etal. (2007) Cadmium triggers an integrated reprogramming of the metabolism of Synechocystis PCC6803, under the control of the Slr1738 regulator. BMC Genomics 8: 350.
13. Imlay, J.A. (2003) Pathways of oxidative damage. Annu Rev Microbiol 57: 395-418.
14. Jeanjean, R., Zuther, E., Yeremenko, N., Havaux, M., Matthijs, H.C., and Hagemann, M. (2003) A photosystem 1 psaFJ-null mutant of the cyanobacterium Synechocystis PCC 6803 expresses the isiAB operon under iron replete conditions. FEBS Lett 549: 52-56.
15. Kanesaki, Y., Yamamoto, H., Paithoonrangsarid, K., Shoumskaya, M., Suzuki, I., Hayashi, H., and Murata, N. (2007) Histidine kinases play important roles in the perception and signal transduction of hydrogen peroxide in the cyanobacterium, Synechocystis sp. PCC 6803. Plant J 49: 313-324.
16. Latifi, A., Jeanjean, R., Lemeille, S., Havaux, M., and Zhang, C.C. (2005) Iron starvation leads to oxidative stress in Anabaena sp. strain PCC 7120. J Bacteriol 187: 6596-6598.
17. Latifi, A., Ruiz, M., and Zhang, C.C. (2009) Oxidative stress in cyanobacteria. FEMS Microbiol Rev 33: 258-278.
18. Lee, J.W., and Helmann, J.D. (2006) The PerR transcription factor senses H2O2 by metal-catalysed histidine oxidation. Nature 440: 363-367.
19. Lemeille, S., Geiselmann, J., and Latifi, A. (2005) Crosstalk regulation among group 2-sigma factors in Synechocystis PCC6803. BMC Microbiol 5: 18.
20. Li, H., Singh, A.K., McIntyre, L.M., and Sherman, L.A. (2004) Differential gene expression in response to hydrogen peroxide and the putative PerR regulon of Synechocystis sp. strain PCC 6803. J Bacteriol 186: 3331-3345.
21. Michel, K.P., Berry, S., Hifney, A., Kruip, J., and Pistorius, E.K. (2003) Adaptation to iron deficiency: a comparison between the cyanobacterium Synechococcus elongatus PCC 7942 wild-type and a DpsA-free mutant. Photosynth Res 75: 71-84.
22. Nodop, A., Pietsch, D., Hocker, R., Becker, A., Pistorius, E.K., Forchhammer, K., and Michel, K.P. (2008) Transcript profiling reveals new insights into the acclimation of the mesophilic fresh-water cyanobacterium Synechococcus elongatus PCC 7942 to iron starvation. Plant Physiol 147: 747-763.
23. Ruiz, M., Bettache, A., Janicki, A., Vinella, D., Zhang, C.C., and Latifi, A. (2010) The alr2505 (osiS) gene from Anabaena sp. strain PCC7120 encodes a cysteine desulfurase induced by oxidative stress. FEBS J 277: 3715-3725.
24. Shih, P.M., Wu, D., Latifi, A., Axen, S.D., Fewer, D.P., Talla, E., etal. (2013) Improving the coverage of the cyanobacterial phylum using diversity-driven genome sequencing. Proc Natl Acad Sci USA 110: 1053-1058.
25. Singh, A.K., McIntyre, L.M., and Sherman, L.A. (2003) Microarray analysis of the genome-wide response to iron deficiency and iron reconstitution in the cyanobacterium Synechocystis sp. PCC 6803. Plant Physiol 132: 1825-1839.
26. Singh, A.K., Li, H., and Sherman, L.A. (2004) Microarray analysis and redox control of gene expression in the cyanobacterium Synechocystis sp. PCC 6803. Physiol Plant 120: 27-35.
27. Stevanovic, M., Hahn, A., Nicolaisen, K., Mirus, O., and Schleiff, E. (2012) The components of the putative iron transport system in the cyanobacterium Anabaena sp. PCC 7120. Environ Microbiol 14: 1655-1670.
28. Storz, G., Tartaglia, L.A., and Ames, B.N. (1990) Transcriptional regulator of oxidative stress-inducible genes: direct activation by oxidation. Science 248: 189-194.
29. Xu, W.L., Jeanjean, R., Liu, Y.D., and Zhang, C.C. (2003) pkn22 (alr2502) encoding a putative Ser/Thr kinase in the cyanobacterium Anabaena sp. PCC 7120 is induced by both iron starvation and oxidative stress and regulates the expression of isiA. FEBS Lett 553: 179-182.
30. Yousef, N., Pistorius, E.K., and Michel, K.P. (2003) Comparative analysis of idiA and isiA transcription under iron starvation and oxidative stress in Synechococcus elongatus PCC 7942 wild-type and selected mutants. Arch Microbiol 180: 471-483.