Joint testing of genotypic and gene-environment interaction identified novel association for BMP4 with non-syndromic CL/P in an asian population using data from an International Cleft Consortium

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Chen, Qianqian ^a,b   Wang, Hong ^a,b   Schwender, Holger ^c   Zhang, Tianxiao ^d   Hetmanski, Jacqueline B ^e   Chou, Yah Huei Wu ^f   Ye, Xiaoqian ^g   Yeow, Vincent ^h   Chong, Samuel S ⁱ   Zhang, Bo ^j   Jabs, Ethylin Wang ^g,k   Parker, Margaret M ^e   Scott, Alan F ^k   Beaty, Terri H ^e  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b BEIJING HOSPITAL   (China)

^c HEINRICH HEINE UNIVERSITY   (Germany)

^d WASHINGTON UNIVERSITY   (United States)

^e JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^f CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^g MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^h K K Women's and Children's Hospital   (Singapore)

ⁱ NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^j XI'AN JIAOTONG UNIVERSITY   (China)

^k JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; TOBACCO SMOKE; BMP4 PROTEIN, HUMAN; PASSIVE SMOKING;

ADULT; ARTICLE; ASIAN; BONE MORPHOGENETIC PROTEIN 4 GENE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; EUROPEAN; FIRST TRIMESTER PREGNANCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE ENVIRONMENT INTERACTION; HOME ENVIRONMENT; HUMAN; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; MOUTH MALFORMATION; NON SYNDROMIC CLEFT LIP WITH CLEFT PALATE; NON SYNDROMIC CLEFT LIP WITHOUT CLEFT PALATE; SINGLE NUCLEOTIDE POLYMORPHISM; WORKPLACE; ADVERSE EFFECTS; ASIAN CONTINENTAL ANCESTRY GROUP; CLEFT LIP; CLEFT PALATE; COMPLICATION; FEMALE; GENETIC LINKAGE; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; PASSIVE SMOKING; PREGNANCY; RISK FACTOR; SMOKING;

ASIAN CONTINENTAL ANCESTRY GROUP; BONE MORPHOGENETIC PROTEIN 4; CLEFT LIP; CLEFT PALATE; FEMALE; GENE-ENVIRONMENT INTERACTION; GENETIC LINKAGE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; MATERNAL EXPOSURE; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANCY; RISK FACTORS; SMOKING; TOBACCO SMOKE POLLUTION;

EID: 84907855742     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0109038     Document Type: Article

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