Synergistic cytotoxic effect of gold nanoparticles and 5-aminolevulinic acid-mediated photodynamic therapy against skin cancer cells

Iranian Journal of Medical Sciences

Volumn 39, Issue 5, 2014, Pages 452-458

  Hadizadeh, Mahnaz ^a   Fateh, Mohsen ^b  

^a IRANIAN RESEARCH ORGANIZATION FOR SCIENCE AND TECHNOLOGY IROST   (Iran)

^b AVICENNA RESEARCH INSTITUTE   (Iran)

Author keywords

Aminolevulinic acid; Nanoparticles; Photochemotherapy

Indexed keywords

AMINOLEVULINIC ACID; GOLD NANOPARTICLE;

ARTICLE; CELL DEATH; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; DRUG POTENTIATION; DRUG SCREENING; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; LIGHT INTENSITY; PHOTODYNAMIC THERAPY; PHOTOTOXICITY; SQUAMOUS CELL CARCINOMA; SQUAMOUS CELL CARCINOMA CELL LINE;

EID: 84907848239     PISSN: 02530716     EISSN: 17353688     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Hopper C. Photodynamic therapy: a clinical reality in the treatment of cancer. Lancet Oncol. 2000;1:212-9. doi: 10.1016/S1470- 2045(00)00166-2. PubMed PMID: 11905638.
2. Ichihara E, Kiura K, Tanimoto M. Targeting angiogenesis in cancer therapy. Acta Med Okayama. 2011;65:353-62. PubMed PMID: 22189475.
3. Lambert JM. Drug-conjugated antibodies for the treatment of cancer. Br J Clin Pharmacol. 2013;76:248-62. doi: 10.1111/bcp.12044. PubMed PMID: 23173552.
4. Touchefeu Y, Harrington KJ, Galmiche JP, Vassaux G. Review article: gene therapy, recent developments and future prospects in gastrointestinal oncology. Aliment Pharmacol Ther. 2010;32:953-68. doi: 10.1111/j.1365- 2036.2010.04424.x. PubMed PMID: 20937041.
5. Dougherty TJ. An update on photodynamic therapy applications. J Clin Laser Med Surg. 2002;20:3-7. doi: 10.1089/104454702753474931. PubMed PMID: 11902352.
6. Garcia-Zuazaga J, Cooper KD, Baron ED. Photodynamic therapy in dermatology: current concepts in the treatment of skin cancer. Expert Rev Anticancer Ther. 2005;5:791-800. doi: 10.1586/14737140.5.5.791. PubMed PMID: 16221049.
7. Almeida RD, Manadas BJ, Carvalho AP, Duarte CB. Intracellular signaling mechanisms in photodynamic therapy. Biochim Biophys Acta. 2004;1704:59-86. doi: 10.1016/j.bbcan.2004.05.003. PubMed PMID: 15363861.
8. Nowis D, Makowski M, Stokłosa T, Legat M, Issat T, Gołab J. Direct tumor damage mechanisms of photodynamic therapy. Acta Biochim Pol. 2005;52:339-52. PubMed PMID: 15990919.
9. Yoo JO, Ha KS. New insights into the mechanisms for photodynamic therapyinduced cancer cell death. Int Rev Cell Mol Biol. 2012;295:139-74. doi: 10.1016/B978- 0-12-394306-4.00010-1. PubMed PMID: 22449489.
10. Postiglione I, Chiaviello A, Palumbo G. Enhancing Photodynamyc Therapy Efficacy by Combination Therapy: Dated, Current and Oncoming Strategies. Cancers. 2011;3:2597-629. doi: 10.3390/cancers3022597.
11. Collaud S, Juzeniene A, Moan J, Lange N. On the selectivity of 5-aminolevulinic acidinduced protoporphyrin IX formation. Curr Med Chem Anticancer Agents. 2004;4:301-16. doi: 10.2174/1568011043352984. PubMed PMID: 15134506.
12. Fukuda H, Casas A, Batlle A. Aminolevulinic acid: from its unique biological function to its star role in photodynamic therapy. Int J Biochem Cell Biol. 2005;37:272-6. doi: 10.1016/j. biocel.2004.04.018. PubMed PMID: 15474973.
13. Wachowska M, Muchowicz A, Firczuk M, Gabrysiak M, Winiarska M, Wańczyk M, et al. Aminolevulinic acid (ALA) as a prodrug in photodynamic therapy of cancer. Molecules. 2011;16:4140-64. doi: 10.3390/ molecules16054140.
14. Tschen EH, Wong DS, Pariser DM, Dunlap FE, Houlihan A, Ferdon MB. Photodynamic therapy using aminolaevulinic acid for patients with nonhyperkeratotic actinic keratoses of the face and scalp: phase IV multicentre clinical trial with 12-month follow up. Br J Dermatol. 2006;155:1262-9. doi: 10.1111/j.1365-2133.2006.07520.x. PubMed PMID: 17107399.
15. Smits T, Kleinpenning MM, van Erp PE, van de Kerkhof PC, Gerritsen MJ. A placebocontrolled randomized study on the clinical effectiveness, immunohistochemical changes and protoporphyrin IX accumulation in fractionated 5-aminolaevulinic acidphotodynamic therapy in patients with psoriasis. Br J Dermatol. 2006;155:429-36. doi: 10.1111/j.1365-2133.2006.07290.x. PubMed PMID: 16882185.
16. Horn M, Wolf P, Wulf HC, Warloe T, Fritsch C, Rhodes LE, et al. Topical methyl aminolaevulinate photodynamic therapy in patients with basal cell carcinoma prone to complications and poor cosmetic outcome with conventional treatment. Br J Dermatol. 2003;149:1242-9. doi: 10.1111/j.1365- 2133.2003.05600.x. PubMed PMID: 14674903.
17. Jain S, Hirst DG, O'Sullivan JM. Gold nanoparticles as novel agents for cancer therapy. Br J Radiol. 2012;85:101-13. doi: 10.1259/bjr/59448833. PubMed PMID: 22010024.
18. Tsai CY, Lu SL, Hu CW, Yeh CS, Lee GB, Lei HY. Size-dependent attenuation of TLR9 signaling by gold nanoparticles in macrophages. J Immunol. 2012;188:68-76. doi: 10.4049/jimmunol.1100344. PubMed PMID: 22156340.
19. Cheng Y, Samia A, Meyers JD, Panagopoulos I, Fei B, Burda C. Highly efficient drug delivery with gold nanoparticle vectors for in vivo photodynamic therapy of cancer. J Am Chem Soc. 2008;130:10643-7. doi: 10.1021/ja801631c. PubMed PMID: 18642918.
20. Wieder ME, Hone DC, Cook MJ, Handsley MM, Gavrilovic J, Russell DA. Intracellular photodynamic therapy with photosensitizernanoparticle conjugates: cancer therapy using a 'Trojan horse'. Photochem Photobiol Sci. 2006;5:727-34. doi: 10.1039/b602830f. PubMed PMID: 16886087.
21. Kimling J, Maier M, Okenve B, Kotaidis V, Ballot H, Plech A. Turkevich method for gold nanoparticle synthesis revisited. J Phys Chem B. 2006;110:15700-7. doi:10.1021/jp061667w. PubMed PMID: 16898714.
22. Li Q, Verschraegen CF, Mendoza J, Hassan R. Cytotoxic activity of the recombinant anti-mesothelin immunotoxin, SS1(dsFv)PE38, towards tumor cell lines established from ascites of patients with peritoneal mesotheliomas. Anticancer Res. 2004;24:1327-35. PubMed PMID: 15274292.
23. Merlin JL, Azzi S, Lignon D, Ramacci C, Zeghari N, Guillemin F. MTT assays allow quick and reliable measurement of the response of human tumour cells to photodynamic therapy. Eur J Cancer. 1992;28A:1452-8. doi: 10.1016/0959-8049(92)90542-A. PubMed PMID: 1387543.
24. Oo MK, Yang X, Du H, Wang H. 5-aminolevulinic acid-conjugated gold nanoparticles for photodynamic therapy of cancer. Nanomedicine. 2008;3:777-86. doi: 10.2217/17435889.3.6.777. PubMed PMID: 19025452.
25. Xu H, Liu C, Mei J, Yao C, Wang S, Wang J,et al. Effects of light irradiation upon photodynamic therapy based on 5-aminolevulinic acid-gold nanoparticle conjugates in K562 cells via singlet oxygen generation. Int J Nanomedicine. 2012;7:5029-38. doi: 10.2147/IJN.S33261. PubMed PMID: 23055721.
26. Uboldi C, Bonacchi D, Lorenzi G, Hermanns MI, Pohl C, Baldi G, et al. Gold nanoparticles induce cytotoxicity in the alveolar type-II cell lines A549 and NCIH441. Part Fibre Toxicol. 2009;6:18. doi: 10.1186/1743- 8977-6-18. PubMed PMID: 19545423.
27. Zhang XD, Guo ML, Wu HY, Sun YM, Ding YQ, Feng X, et al. Irradiation stability and cytotoxicity of gold nanoparticles for radiotherapy. Int J Nanomedicine. 2009;4:165-73. doi: 10.2147/ IJN.S6723. PubMed PMID: 19774115.
28. Coulter JA, Jain S, Butterworth KT, Taggart LE, Dickson GR, McMahon SJ, et al. Cell type-dependent uptake, localization, and cytotoxicity of 1.9 nm gold nanoparticles. Int J Nanomedicine. 2012;7:2673-85. doi: 10.2147/ IJN.S31751. PubMed PMID: 22701316.
29. Hvolbæk B, Janssens TV, Clausen BS, Falsig H, Christensen CH, Nørskov JK. Catalyticactivity of Au nanoparticles. Nano Today. 2007;2:14-8. doi: 10.1016/ S1748-0132(07)70113-5.
30. Berlanda J, Kiesslich T, Engelhardt V, Krammer B, Plaetzer K. J Photochem Photobiol B. J Photochem Photobiol B. 2010;100:173-80. doi: 10.1016/j.jphotobiol.2010.06.004. PubMed PMID: 20599390.
31. Battah S, Balaratnam S, Casas A, O'Neill S, Edwards C, Batlle A, et al. Macromolecular delivery of 5-aminolaevulinic acid for photodynamic therapy using dendrimer conjugates. Mol Cancer Ther. 2007;6:876-85. doi: 10.1158/1535-7163.MCT-06-0359. PubMed PMID: 17363482.