Neuroprotection of a novel cyclopeptide C∗HSDGIC∗ from the cyclization of PACAP (1-5) in cellular and rodent models of retinal ganglion cell apoptosis

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Cheng, Huanhuan ^a   Ding, Yong ^b   Yu, Rongjie ^c   Chen, Jiansu ^d   Wu, Chunyun ^d  

^a THE THIRD AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF JINAN UNIVERSITY   (China)

^c JINAN UNIVERSITY   (China)

^d MEDICAL COLLEGE OF JINAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; THY 1 ANTIGEN; BENZIMIDAZOLE DERIVATIVE; HOE 33342; N METHYLASPARTIC ACID; NEUROPROTECTIVE AGENT;

A WAVE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; B WAVE; CELL LINE; CELL LOSS; CELL VIABILITY; CONTROLLED STUDY; CYCLIZATION; DRUG EFFECT; ELECTRORETINOGRAPHY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MTT ASSAY; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PHOTOPIC VISION; PHOTOSENSITIVITY; PROTEIN EXPRESSION; RAT; RETINA GANGLION CELL; RGC 5 CELL LINE; RODENT MODEL; ULTRAVIOLET B RADIATION; WESTERN BLOTTING; AMINO ACID SEQUENCE; ANIMAL; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; METABOLISM; MITOCHONDRION; MOLECULAR GENETICS; SPRAGUE DAWLEY RAT; ULTRAVIOLET RADIATION; VISION;

RODENTIA;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BENZIMIDAZOLES; BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; CYCLIZATION; ELECTRORETINOGRAPHY; MITOCHONDRIA; MODELS, ANIMAL; MOLECULAR SEQUENCE DATA; N-METHYLASPARTATE; NEUROPROTECTIVE AGENTS; PEPTIDES, CYCLIC; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RETINAL GANGLION CELLS; ULTRAVIOLET RAYS; VISION, OCULAR;

EID: 84907841734     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108090     Document Type: Article

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