Method development and validation for simultaneous quantification of 15 drugs of abuse and prescription drugs and 7 of their metabolites in whole blood relevant in the context of driving under the influence of drugs--Usefulness of multi-analyte calibration

Forensic Science International

Volumn 244, Issue , 2014, Pages 92-101

  Steuer, Andrea E ^a   Forss, Anna Maria ^a   Dally, Annika M ^a   Kraemer, Thomas ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

DUID; LC MS MS; Multi analyte approach; Validation

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; 3,4 METHYLENEDIOXYMETHAMPHETAMINE; BENZOYLECGONINE; CODEINE; DIHYDROCODEINE; DRUG METABOLITE; HYDROCODONE; HYDROMORPHONE; METHADONE; METHAMPHETAMINE; METHYLPHENIDATE; MORPHINE; MORPHINE 6 ACETATE; N ETHYL 3,4 METHYLENEDIOXYAMPHETAMINE; OXYCODONE; OXYMORPHONE; PRESCRIPTION DRUG; TRAMADOL; ZOLPIDEM; NARCOTIC AGENT;

ANALYTE RECOVERY; ANALYTICAL PARAMETERS; ARTICLE; BLOOD SAMPLING; CALIBRATION; CAR DRIVING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRIVING UNDER THE INFLUENCE OF DRUG; DRUG ABUSE; DRUG ANALYSIS; DRUG DETERMINATION; HUMAN; INTERMETHOD COMPARISON; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MASS FRAGMENTOGRAPHY; MASS SPECTROMETRY; MATRIX EFFECT; MEASUREMENT ACCURACY; MEASUREMENT PRECISION; MULTI ANALYTE CALIBRATION; MULTIPLE REACTION MONITORING MODE; QUALITY CONTROL; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; THERMOSTABILITY; VALIDATION STUDY; BLOOD; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LEGISLATION AND JURISPRUDENCE; PROCEDURES; SUBSTANCE ABUSE;

AUTOMOBILE DRIVING; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; MASS SPECTROMETRY; NARCOTICS; PRESCRIPTION DRUGS; SOLID PHASE EXTRACTION; SUBSTANCE ABUSE DETECTION;

EID: 84907788287     PISSN: 03790738     EISSN: 18726283     Source Type: Journal    
DOI: 10.1016/j.forsciint.2014.08.022     Document Type: Article

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