Effects of deep hypothermic circulatory arrest on the blood brain barrier in a cardiopulmonary bypass model - a pilot study

Heart Lung and Circulation

Volumn 23, Issue 10, 2014, Pages 981-984

  Bartels, Karsten ^a   Ma, Qing ^a   Venkatraman, Talaignair N ^a   Campos, Christopher R ^b   Smith, Lindsay ^b   Cannon, Ronald E ^b   Podgoreanu, Mihai V ^a   Lascola, Christopher D ^a   Miller, David S ^b   Mathew, Joseph P ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Blood brain barrier; Cardiac surgery; Cardiopulmonary bypass; Deep hypothermic circulatory arrest; Neurologic injury

Indexed keywords

ALBUMIN; CLAUDIN 5; GADOBUTROL; OCCLUDIN; CONTRAST MEDIUM; MULTIDRUG RESISTANCE PROTEIN; ORGANOMETALLIC COMPOUND;

ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN; BRAIN CAPILLARY; BRAIN FUNCTION; BRAIN PARENCHYMA; BRAIN VENTRICLE PRESSURE; CARDIOPULMONARY BYPASS; CONTROLLED STUDY; DEEP HYPOTHERMIC CIRCULATORY ARREST; IN VIVO STUDY; MALE; MOLECULAR WEIGHT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; PILOT STUDY; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; RODENT MODEL; SHAM PROCEDURE; WESTERN BLOTTING; ADVERSE EFFECTS; ANIMAL; ANIMAL MODEL; METABOLISM; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; BLOOD-BRAIN BARRIER; CARDIOPULMONARY BYPASS; CIRCULATORY ARREST, DEEP HYPOTHERMIA INDUCED; CLAUDIN-5; CONTRAST MEDIA; MAGNETIC RESONANCE IMAGING; MALE; MODELS, ANIMAL; OCCLUDIN; ORGANOMETALLIC COMPOUNDS; P-GLYCOPROTEIN; PILOT PROJECTS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84907736598     PISSN: 14439506     EISSN: 14442892     Source Type: Journal    
DOI: 10.1016/j.hlc.2014.04.131     Document Type: Article

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