HIPPO Pathway Members Restrict SOX2 to the Inner Cell Mass Where It Promotes ICM Fates in the Mouse Blastocyst

PLoS Genetics

Volumn 10, Issue 10, 2014, Pages

  Wicklow, Eryn ^a   Blij, Stephanie ^a   Frum, Tristan ^a,d   Hirate, Yoshikazu ^b,e   Lang, Richard A ^c   Sasaki, Hiroshi ^b   Ralston, Amy ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b KUMAMOTO UNIVERSITY   (Japan)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^d Michigan State University   (United States)

^e TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 4; LATS2; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN; TEAD4; TRANSCRIPTION FACTOR CDX2; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; WWTR1; YAP; HIPPO PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; NANOG PROTEIN, MOUSE; POU5F1 PROTEIN, MOUSE; PROTEIN SERINE THREONINE KINASE; SOX2 PROTEIN, MOUSE; TRANSCRIPTION FACTOR SOX;

ANIMAL TISSUE; ARTICLE; BLASTOCYST; CELL FATE; CONTROLLED STUDY; EMBRYO; EMBRYO MEMBRANE; EMBRYO PATTERN FORMATION; ENDODERM; GENE CONTROL; GENE EXPRESSION; HIPPO PATHWAY; INNER CELL MASS; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; SIGNAL TRANSDUCTION; TROPHECTODERM; ANIMAL; CELL DIFFERENTIATION; CELL LINEAGE; CYTOLOGY; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING;

ANIMALS; BLASTOCYST; BLASTOCYST INNER CELL MASS; CELL DIFFERENTIATION; CELL LINEAGE; EMBRYONIC DEVELOPMENT; EMBRYONIC STEM CELLS; ENDODERM; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; MICE; OCTAMER TRANSCRIPTION FACTOR-3; PLURIPOTENT STEM CELLS; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; SOXB1 TRANSCRIPTION FACTORS;

EID: 84907735517     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004618     Document Type: Article

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