Salivary inflammatory cytokines may be novel markers of carotid atherosclerosis in a Japanese general population: The Suita study

Atherosclerosis

Volumn 237, Issue 1, 2014, Pages 123-128

  Kosaka, Takayuki ^a   Kokubo, Yoshihiro ^b   Ono, Takahiro ^a   Sekine, Shinichi ^a   Kida, Momoyo ^a   Kikui, Miki ^a   Yamamoto, Masaaki ^a   Watanabe, Makoto ^b   Amano, Atsuo ^a   Maeda, Yoshinobu ^a   Miyamoto, Yoshihiro ^b  

^a OSAKA UNIVERSITY   (Japan)

^b NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Carotid atherosclerosis; Intima media thickness; Periodontal disease; Salivary inflammatory cytokine

Indexed keywords

CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

AGED; ARTERIAL WALL THICKNESS; ARTICLE; CAROTID ATHEROSCLEROSIS; ECHOGRAPHY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; JAPANESE (PEOPLE); MAJOR CLINICAL STUDY; MALE; PERIODONTAL DISEASE; POPULATION; SALIVA; STENOSIS; URBAN POPULATION; ATHEROSCLEROSIS; BLOOD; CAROTID ARTERY; CAROTID ARTERY DISEASE; ETHNOLOGY; INFLAMMATION; JAPAN; METABOLISM; MIDDLE AGED; MULTIVARIATE ANALYSIS; RISK; RISK FACTOR; STATISTICAL MODEL;

AGED; ATHEROSCLEROSIS; CAROTID ARTERIES; CAROTID ARTERY DISEASES; CAROTID INTIMA-MEDIA THICKNESS; CYTOKINES; DINOPROSTONE; FEMALE; HUMANS; INFLAMMATION; INTERLEUKIN-1BETA; INTERLEUKIN-6; JAPAN; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; ODDS RATIO; RISK FACTORS; SALIVA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84907735279     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2014.08.046     Document Type: Article

References (29)

1. Gokulakrishnan K., Deepa R., Mohan V. Association of high sensitivity C-reactive protein (hsCRP) and tumor necrosis factor-alpha (TNF-alpha) with carotid intimal medial thickness in subjects with different grades of glucose intolerance- the Chennai Urban Rural Epidemiology Study (CURE-31). Clin Biochem 2008, 41:480-485.
2. Sardo M.A., Mandraffino G., Campo S., Saitta C., Bitto A., Alibrandi A., et al. Biglycan expression in hypertensive subjects with normal or increased carotid intima-media wall thickness. Clin Chim Acta. 2009, 406:89-93.
3. Pizzi C., Manzoli L., Mancini S., Bedetti G., Fontana F., Costa G.M. Autonomic nervous system, inflammation and preclinical carotid atherosclerosis in depressed subjects with coronary risk factors. Atherosclerosis 2010, 212:292-298.
4. Okazaki S., Furukado S., Abe Y., Tanaka M., Miwa K., Yamagami H., et al. Cerebrovasc Dis 2010, 30:180-187.
5. Scuteri A., Orru M., Morrell C., Piras M.G., Taub D., Schlessinger D., et al. Independent and additive effects of cytokine patterns and the metabolic syndrome on arterial aging in the SardiNIA Study. Atherosclerosis 2011, 215:459-464.
6. Freitas W.M., Quaqlia L.A., Santos S.N., Soares A.A., Japiassú A.V., Boaventura V., et al. Association of systemic inflammatory activity with coronary and carotid atherosclerosis in the very elderly. Atherosclerosis 2011, 216:212-216.
7. Liu Z., Lu F., Pan H., Zhao Y., Wang S., Sun S., et al. Correlation of peripheral Th17 cells and Th17-associated cytokines to the severity of carotid artery plaque and its clinical implication. Atherosclerosis 2012, 221:232-241.
8. Guarneri M., Geraci C., Incalcaterra F., Arsena R., Mule G., Vaccaro F., et al. Subclinical atherosclerosis and fetuin-A plasma levels in essential hypertensive patients. Hypertens Res 2013, 36:129-133.
9. Beloqui Q., Páramo J.A., Orbe J., Benito A., Colina I., Monasterio A., et al. Monocyte cyclooxygenase-2 overactivity: a new marker of subclinical atherosclerosis in asymptomatic subjects with cardiovascular risk factors?. Eur Heart J 2005, 26:153-158.
10. Bahekar A.A., Singh S., Saha S., Molnar J., Arora R. The prevalence and incidence of coronary heart disease is significantly increased in periodontitis: a meta-analysis. Am Heart J 2007, 154:830-837.
11. Lopez-Jornet P., Berna-Mestre J.D., Berna-Serna J.D., Camacho-Alonso F., Fernandez-Millan S., Reus-Pintado M. Measurement of atherosclerosis markers in patients with periodontitis: a case-control study. JPeriodontol 2012, 83:690-698.
12. Genco R., Offenbacher S., Beck J. Periodontal disease and cardiovascular disease: epidemiology and possible mechanisms. JAm Dent Assoc 2002, 133:14S-22S.
13. Kapellas K., Maple-Brown L.J., Jamieson L.M., Do L.G., O'Dea K., Brown A., et al. Effect of periodontal therapy on arterial structure and function among aboriginal Australians: a randomized, controlled trial. Hypertension 2014, 10.1161/HYPERTENSIONAHA.114.03359.
14. Sexton W.M., Lin Y., Kryscio R.J., Dawson D.R., Ebersole J.L., Miller C.S. Salivary biomarkers of periodontal disease in response to treatment. JClin Periodontol 2011, 38:434-441.
15. Yoon A.J., Cheng B., Philipone E., Tumer R., Lamster I.B. Inflammatory biomarkers in saliva: assessing the strength of association of diabetes mellitus and periodontal status with the oral inflammatory burden. JClin Periodontol 2012, 39:434-440.
16. Lee A., Ghaname C.B., Braun T.M., Suqai J.V., Teles R.P., Loesche W.J., et al. Bacterial and salivary biomarkers predict the gingival inflammatory profile. JPeriodontol 2013, 83:79-89.
17. Yue Y., Liu Q., Xu C., Loo W.T., Wang M., Wen G., et al. Comparative evaluation of cytokines in gingival crevicular fluid and saliva of patients with aggressive periodontitis. Int J Biol Markers 2013, 28:108-112.
18. Nomura Y., Shimada Y., Hanada N., Numabe Y., Kamoi K., Sato T., et al. Salivary biomarkers for predicting the progression of chronic periodontitis. Arch Oral Biol 2012, 57:413-420.
19. Kokubo Y., Kamide K., Okamura T., Watanabe M., Higashiyama A., Kawanishi K., et al. Impact of high-normal blood pressure on the risk of cardiovascular disease in a Japanese urban cohort: the Suita study. Hypertension 2008, 52:652-659.
20. Ohara T., Kokubo Y., Toyoda K., Watanabe M., Koga M., Nakamura S., et al. Impact of chronic kidney disease on carotid atherosclerosis according to blood pressure category: the Suita study. Stroke 2013, 44:3537-3539.
21. Ainamo J., Barmes D., Beagrie G., Cutress T., Martin J., Sardo-Infirri J., et al. Development of the World Health Organization (WHO) community periodontal Index of treatment needs (CPITN). Int Dent J 1982, 32:281-291.
22. Yang C., Xiao L., Tongren J.E., Sullivan J., Lal A.A., Collins W.E. Cytokine production in rhesus monkeys infected with Plasmodium coatneyi. Am J Trop Med Hyg 1999, 61:226-229.
23. Shimamoto K., Ando K., Fujita T., Hasebe N., Higaki J., Horiuchi M., et al. The Japanese society of hypertension guidelines for the management of hypertension (JSH 2014). Hypertens Res 2014, 37:253-387.
24. Vita J.A., Loscalzo J. Shouldering the risk factor burden: infection, atherosclerosis, and the vascular endothelium. Circulation 2002, 106:164-166.
25. Higashi Y., Goto C., Jitsuki D., Umemura T., Nishioka K., Takemoto H., et al. Periodontal infection is associated with endothelial dysfunction in healthy subjects and hypertensive patients. Hypertension 2008, 51:446-453.
26. Epstein S.E., Zhou Y.F., Zhu J. Infection and atherosclerosis: emerging mechanistic paradigms. Circulation 1999, 100:e20-e28.
27. Nakashima A., Yorioka N., Asakimori Y., Ito T., Masaki T., Shigemoto K., et al. Different risk factors for the maximum and the mean carotid intima-media thickness in hemodialysis patients. Intern Med 2003, 42:1095-1099.
28. Labat C., Temmar M., Nagy E., Bean K., Brink C., Benetos A., et al. Inflammatory mediators in saliva associated with arterial stiffness and subclinical atherosclerosis. JHypertens 2013, 31:2251-2258.
29. Joldersma M., Klein-Nulend J., Oleksik A.M., Heyligers I.C., Burger E.H. Estrogen enhances mechanical stess-induced prostaglandin production by bone cells from elderly women. Am J Physiol Endocrinol Metab 2001, 280:436-442.