Measurement of atherosclerosis markers in patients with periodontitis: A Case-control study

Journal of Periodontology

Volumn 83, Issue 6, 2012, Pages 690-698

  Lopez Jornet P ^a   Berna Mestre J D ^a   Berna Serna J D ^a   Camacho Alonso, F ^a   Fernandez Millan, S ^a   Reus Pintado, M ^a  

^a UNIVERSITY OF MURCIA   (Spain)

Author keywords

Carotid artery diseases; Case control study; Inflammation; Periodontitis; Risk factor; Statistical

Indexed keywords

AUTACOID; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CHOLESTEROL; GLYCOSYLATED HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; AGE; AGED; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BLOOD; BLOOD PRESSURE; CAROTID ARTERY DISEASE; CASE CONTROL STUDY; CHRONIC PERIODONTITIS; CLASSIFICATION; COMPARATIVE STUDY; ECHOGRAPHY; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; INTERNAL CAROTID ARTERY; INTIMA; MALE; MIDDLE AGED; PERIODONTAL DISEASE; PERIODONTICS; PHYSIOLOGY; TUNICA MEDIA;

ADULT; AGE FACTORS; AGED; ATHEROSCLEROSIS; BIOLOGICAL MARKERS; BLOOD GLUCOSE; BLOOD PRESSURE; C-REACTIVE PROTEIN; CAROTID ARTERY DISEASES; CAROTID ARTERY, INTERNAL; CASE-CONTROL STUDIES; CHOLESTEROL; CHOLESTEROL, HDL; CHOLESTEROL, LDL; CHRONIC PERIODONTITIS; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INFLAMMATION MEDIATORS; MALE; MIDDLE AGED; PERIODONTAL ATTACHMENT LOSS; PERIODONTAL INDEX; PLAQUE, ATHEROSCLEROTIC; TRIGLYCERIDES; TUNICA INTIMA; TUNICA MEDIA;

EID: 84861796252     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2011.110412     Document Type: Article

References (36)

1. Beck JD, Offenbacher S. Systemic effects of periodontitis: Epidemiology of periodontal disease and cardiovascular disease. J Periodontol 2005;76(Suppl. 11):2089-2100.
2. Meurman JH, Sanz M, Janket SJ. Oral health, atherosclerosis, and cardiovascular disease. Crit Rev Oral Biol Med 2004;15:403-413.
3. Joshipura KJ, Wand HC, Merchant AT, Rimm EB. Periodontal disease and biomarkers related to cardiovascular disease. J Dent Res 2004;83:151-155.
4. Oyama N, Gona P, Salton CJ, et al. Differential impact of age, sex, and hypertension on aortic atherosclerosis: The Framingham Heart Study. Arterioscler Thromb Vasc Biol 2008;28:155-159.
5. Desvarieux M, Demmer RT, Rundek T, et al; Oral Infections and Vascular Disease Epidemiology Study (INVEST). Relationship between periodontal disease, tooth loss, and carotid artery plaque: The Oral Infections and Vascular Disease Epidemiology Study (INVEST). Stroke 2003;34:2120-2125.
6. Desvarieux M, Demmer RT, Rundek T, et al. Periodontal microbiota and carotid intima-media thickness: The Oral Infections and Vascular Disease Epidemiology Study (INVEST). Circulation 2005;111:576-582.
7. Bahekar AA, Singh S, Saha S, Molnar J, Arora R. The prevalence and incidence of coronary heart disease is significantly increased in periodontitis: A meta-analysis. Am Heart J 2007;154:830-837.
8. Cueto A, Mesa F, Bravo M, Ocaña-Riola R. Periodontitis as risk factor for acute myocardial infarction. A case control study of Spanish adults. J Periodontal Res 2005;40:36-42.
9. Ridker PM, Silvertown JD. Inflammation, C-reactive protein, and atherothrombosis. J Periodontol 2008; 79(Suppl. 8):1544-1551.
10. Mustapha IZ, Debrey S, Oladubu M, Ugarte R. Markers of systemic bacterial exposure in periodontal disease and cardiovascular disease risk: A systematic review and meta-analysis. J Periodontol 2007;78:2289-2302.
11. Persson GR, Pettersson T, Ohlsson O, Renvert S. High-sensitivity serum C-reactive protein levels in subjects with or without myocardial infarction or periodontitis. J Clin Periodontol 2005;32:219-224.
12. Offenbacher S, Beck JD, Moss K, et al. Results from the Periodontitis and Vascular Events (PAVE) Study: A pilot multicentered, randomized, controlled trial to study effects of periodontal therapy in a secondary prevention model of cardiovascular disease. J Peri-odontol 2009;80:190-201.
13. Grau AJ, Becher H, Ziegler CM, et al. Periodontal disease as a risk factor for ischemic stroke. Stroke 2004;35:496-501.
14. Scannapieco FA, Bush RB, Paju S. Associations between periodontal disease and risk for atherosclerosis, cardiovascular disease, and stroke. A systematic review. Ann Periodontol 2003;8:38-53.
15. Kiechl S, Egger G, Mayr M, et al. Chronic infections and the risk of carotid atherosclerosis: Prospective results from a large population study. Circulation 2001;103: 1064-1070.
16. Hujoel PP, Drangsholt M, Spiekerman C, DeRouen TA. Periodontal disease and coronary heart disease risk. JAMA 2000;284:1406-1410.
17. Desvarieux M, Demmer RT, Jacobs DR Jr, et al. Periodontal bacteria and hypertension: The oral infections and vascular disease epidemiology study (INVEST). J Hypertens 2010;28:1413-1421.
18. Beck JD, Elter JR, Heiss G, Couper D, Mauriello SM, Offenbacher S. Relationship of periodontal disease to carotid artery intima-media wall thickness: The atherosclerosis risk in communities (ARIC) study. Arterioscler Thromb Vasc Biol 2001;21:1816-1822.
19. Burke GL, Evans GW, Riley WA, et al. Arterial wall thickness is associated with prevalent cardiovascular disease in middle-aged adults. The Atherosclerosis Risk in Communities (ARIC) Study. Stroke 1995;26: 386-391.
20. Pignoli P, Tremoli E, Poli A, Oreste P, Paoletti R. Intimal plus medial thickness of the arterial wall: A direct measurement with ultrasound imaging. Circulation 1986;74:1399-1406.
21. Chambless LE, Heiss G, Folsom AR, et al. Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: The Atherosclerosis Risk in Communities (ARIC) Study, 1987-1993. Am JEpidemiol 1997;146:483-494.
22. Salonen JT, Salonen R. Ultrasonographically assessed carotid morphology and the risk of coronary heart disease. Arterioscler Thromb 1991;11:1245-1249.
23. Bots ML, Hoes AW, Koudstaal PJ, Hofman A, Grobbee DE. Common carotid intima-media thickness and risk of stroke and myocardial infarction: The Rotterdam Study. Circulation 1997;96:1432-1437.
24. O'Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson SK Jr; Cardiovascular Health Study Collaborative Research Group. Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. N Engl J Med 1999; 340:14-22.
25. Chambless LE, Folsom AR, Clegg LX, et al. Carotid wall thickness is predictive of incident clinical stroke: The Atherosclerosis Risk in Communities (ARIC) study. Am J Epidemiol 2000;151:478-487.
26. Leivadaros E, van der Velden U, Bizzarro S, et al. A pilot study into measurements of markers of atherosclerosis in periodontitis. J Periodontol 2005;76:121-128.
27. Cairo F, Castellani S, Gori AM, et al. Severe periodontitis in young adults is associated with sub-clinical atherosclerosis. J Clin Periodontol 2008;35:465-472.
28. Persson GR, Persson RE. Cardiovascular disease and periodontitis: An update on the associations and risk. J Clin Periodontol 2008; 35(Suppl. 8)362-379.
29. Velázquez F, Berná JD, Abellán JL, Serrano L, Escribano A, Canteras M. Reproducibility of sonographic measurements of carotid intima-media thickness. Acta Radiol 2008;49:1162-1166.
30. Debette S, Leone N, Courbon D, et al. Calf circumference is inversely associated with carotid plaques. Stroke 2008;39:2958-2965.
31. Cao JJ, Arnold AM, Manolio TA, et al. Association of carotid artery intima-media thickness, plaques, and C-protein with future cardiovascular disease and allcause mortality: The Cardiovascular Health Study. Circulation 2007;116:32-38.
32. Elter JR, Champagne CM, Offenbacher S, Beck JD. Relationship of periodontal disease and tooth loss to prevalence of coronary heart disease. J Periodontol 2004;75:782-790.
33. Andriankaja OM, Genco RJ, Dorn J, et al. Periodontal disease and risk of myocardial infarction: The role of gender and smoking. Eur J Epidemiol 2007;22:699-705.
34. Tonetti MS, D'Aiuto F, Nibali L, et al. Treatment of periodontitis and endothelial function. N Engl J Med 2007;356:911-920.
35. Genco RJ, Grossi SG, Ho A, Nishimura F, Murayama Y. A proposed model linking inflammation to obesity, diabetes, and periodontal infections. J Periodontol 2005; 76(Suppl. 11):2075-2084.
36. Chaffee BW, Weston SJ. Association between chronic periodontal disease and obesity: A systematic review and meta-analysis. J Periodontol 2010;81:1708-1724.