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Volumn 124, Issue 14, 2014, Pages 2168-2169

Less Jak2 makes more platelets

Author keywords

[No Author keywords available]

Indexed keywords

JANUS KINASE 2; THROMBOPOIETIN; JAK2 PROTEIN, MOUSE;

EID: 84907699056     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-08-596361     Document Type: Review
Times cited : (8)

References (10)
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    • Genetic studies reveal an unexpected negative regulatory role for Jak2 in thrombopoiesis
    • Meyer SC, Keller MD, Woods BA, et al. Genetic studies reveal an unexpected negative regulatory role for Jak2 in thrombopoiesis. Blood. 2014;124(14):2280-2284.
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    • Meyer, S.C.1    Keller, M.D.2    Woods, B.A.3
  • 2
    • 18244432009 scopus 로고    scopus 로고
    • Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis
    • Neubauer H, Cumano A, Müller M, Wu H, Huffstadt U, Pfeffer K. Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis. Cell. 1998;93(3):397-409.
    • (1998) Cell , vol.93 , Issue.3 , pp. 397-409
    • Neubauer, H.1    Cumano, A.2    Müller, M.3    Wu, H.4    Huffstadt, U.5    Pfeffer, K.6
  • 3
    • 84875424883 scopus 로고    scopus 로고
    • Conditional deletion of Jak2 reveals an essential role in hematopoiesis throughout mouse ontogeny: Implications for Jak2 inhibition in humans
    • Park SO, Wamsley HL, Bae K, et al. Conditional deletion of Jak2 reveals an essential role in hematopoiesis throughout mouse ontogeny: Implications for Jak2 inhibition in humans. PLoS ONE. 2013;8(3):e59675.
    • (2013) PLoS ONE , vol.8 , Issue.3 , pp. e59675
    • Park, S.O.1    Wamsley, H.L.2    Bae, K.3
  • 4
    • 84897459913 scopus 로고    scopus 로고
    • Selective deletion of Jak2 in adult mouse hematopoietic cells leads to lethal anemia and thrombocytopenia
    • Grisouard J, Hao-Shen H, Dirnhofer S, Wagner KU, Skoda RC. Selective deletion of Jak2 in adult mouse hematopoietic cells leads to lethal anemia and thrombocytopenia. Haematologica. 2014;99(4):e52-e54.
    • (2014) Haematologica , vol.99 , Issue.4 , pp. e52-e54
    • Grisouard, J.1    Hao-Shen, H.2    Dirnhofer, S.3    Wagner, K.U.4    Skoda, R.C.5
  • 5
    • 84899095747 scopus 로고    scopus 로고
    • Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferation
    • Ng AP, Kauppi M, Metcalf D, et al. Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferation. Proc Natl Acad Sci USA. 2014;111(16):5884-5889.
    • (2014) Proc Natl Acad Sci USA , vol.111 , Issue.16 , pp. 5884-5889
    • Ng, A.P.1    Kauppi, M.2    Metcalf, D.3
  • 6
    • 0029030356 scopus 로고
    • The reciprocal relationship of thrombopoietin (c-Mpl ligand) to changes in the platelet mass during busulfan-induced thrombocytopenia in the rabbit
    • Kuter DJ, Rosenberg RD. The reciprocal relationship of thrombopoietin (c-Mpl ligand) to changes in the platelet mass during busulfan-induced thrombocytopenia in the rabbit. Blood. 1995;85(10):2720-2730.
    • (1995) Blood , vol.85 , Issue.10 , pp. 2720-2730
    • Kuter, D.J.1    Rosenberg, R.D.2
  • 7
    • 0030048887 scopus 로고    scopus 로고
    • Thrombopoietin in thrombocytopenic mice: Evidence against regulation at the mRNA level and for a direct regulatory role of platelets
    • Stoffel R, Wiestner A, Skoda RC. Thrombopoietin in thrombocytopenic mice: evidence against regulation at the mRNA level and for a direct regulatory role of platelets. Blood. 1996;87(2):567-573.
    • (1996) Blood , vol.87 , Issue.2 , pp. 567-573
    • Stoffel, R.1    Wiestner, A.2    Skoda, R.C.3
  • 8
    • 0029865443 scopus 로고    scopus 로고
    • Regulation of thrombopoietin levels by c-mpl-mediated binding to platelets
    • Fielder PJ, Gurney AL, Stefanich E, et al. Regulation of thrombopoietin levels by c-mpl-mediated binding to platelets. Blood. 1996;87(6):2154-2161.
    • (1996) Blood , vol.87 , Issue.6 , pp. 2154-2161
    • Fielder, P.J.1    Gurney, A.L.2    Stefanich, E.3
  • 9
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    • Incomplete restoration ofMpl expression in the mpl-/- mouse produces partial correction of the stem cell-repopulating defect and paradoxical thrombocytosis
    • Lannutti BJ, Epp A, Roy J, Chen J, Josephson NC. Incomplete restoration ofMpl expression in the mpl-/- mouse produces partial correction of the stem cell-repopulating defect and paradoxical thrombocytosis. Blood. 2009; 113(8):1778-1785.
    • (2009) Blood , vol.113 , Issue.8 , pp. 1778-1785
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  • 10
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    • Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes
    • Tiedt R, Coers J, Ziegler S, et al. Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes. Blood. 2009;113(8):1768-1777.
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    • Tiedt, R.1    Coers, J.2    Ziegler, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.