Prolonged reaction to mental arithmetic stress in first-degree relatives of schizophrenia patients

Clinical Schizophrenia and Related Psychoses

Volumn 8, Issue 3, 2014, Pages 137-142

  Abhishekh, Hulegar A ^a   Kumar, Naveen C ^b   Thirthalli, Jagadisha ^b   Chandrashekar, H ^a   Gangadhar, Bangalore N ^b   Sathyaprabha, Talakad N ^b  

^a Bengaluru Medical College and Research Institute   (India)

^b NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

Author keywords

Arithmetic stress test; Endophenotype; First degree relatives; Heart rate variability; Schizophrenia

Indexed keywords

ADULT; ARTICLE; AUTONOMIC DYSFUNCTION; AUTONOMIC NERVOUS SYSTEM FUNCTION; BIOLOGICAL TRAIT; CONTROLLED STUDY; CONVALESCENCE; FEMALE; FIRST DEGREE RELATIVE; HEART RATE VARIABILITY; HUMAN; HUMAN EXPERIMENT; MALE; MENTAL ARITHMETIC; MENTAL STRESS; NORMAL HUMAN; SCHIZOPHRENIA; TASK PERFORMANCE; AUTONOMIC NERVOUS SYSTEM; FAMILY; HEART RATE; INDIA; MATHEMATICS; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOLOGY; TIME;

ADULT; AUTONOMIC NERVOUS SYSTEM; FAMILY; FEMALE; HEART RATE; HUMANS; INDIA; MALE; MATHEMATICS; SCHIZOPHRENIA; STRESS, PSYCHOLOGICAL; TASK PERFORMANCE AND ANALYSIS; TIME;

EID: 84907685668     PISSN: 19351232     EISSN: 19412010     Source Type: Journal    
DOI: 10.3371/CSRP.ABKU.022213     Document Type: Article

References (32)

1. Toichi M, Kubota Y, Murai T, Kamio Y, Sakihama M, Toriuchi T, et al. The influence of psychotic states on the autonomic nervous system in schizophrenia. Int J Psychophysiol 1999;31(2): 147-154.
2. Bar KJ, Letzsch A, Jochum T, Wagner G, Greiner W, Sauer H. Loss of efferent vagal activity in acute schizophrenia. J Psychiatr Res 2005;39(5): 519-527.
3. Bar KJ, Boettger MK, Koschke M, Schulz S, Chokka P, Yeragani VK, et al. Non-linear complexity measures of heart rate variability in acute schizophrenia. Clin Neurophysiol 2007;118(9): 2009-2015.
4. Peupelmann J, Quick C, Berger S, Hocke M, Tancer ME, Yeragani VK, et al. Linear and non-linear measures indicate gastric dysmotility in patients suffering from acute schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 2009;33(7): 1236-1240.
5. Bar KJ, Boettger MK, Schulz S, Harzendorf C, Agelink MW, Yeragani VK, et al. The interaction between pupil function and cardiovascular regulation in patients with acute schizophrenia. Clin Neurophysiol 2008;119(10): 2209-2213.
6. Peupelmann J, Boettger MK, Ruhland C, Berger S, Ramachandraiah CT, Yeragani VK, et al. Cardio-respiratory coupling indicates suppression of vagal activity in acute schizophrenia. Schizophr Res 2009;112(1-3): 153-157.
7. Berger S, Boettger MK, Tancer M, Guinjoan SM, Yeragani VK, Bar KJ. Reduced cardio-respiratory coupling indicates suppression of vagal activity in healthy relatives of patients with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 2010;34(2): 406-411.
8. Bar KJ, Berger S, Metzner M, Boettger MK, Schulz S, Ramachandraiah CT, et al. Autonomic dysfunction in unaffected first-degree relatives of patients suffering from schizophrenia. Schizophr Bull 2010;36(5): 1050-1058.
9. Castro MN, Vigo DE, Chu EM, Fahrer RD, de Achaval D, Costanzo EY, et al. Heart rate variability response to mental arithmetic stress is abnormal in first-degree relatives of individuals with schizophrenia. Schizophr Res 2009;109(1-3): 134-140.
10. Berger S, Hocke M, Bar KJ. Gastric dysmotility in healthy first-degree relatives of patients with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 2010;34(7): 1294-1299.
11. Heart rate variability. Standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Circulation 1996;93(5): 1043-1065.
12. Singh JP, Larson MG, O'Donnell CJ, Tsuji H, Evans JC, Levy D. Heritability of heart rate variability: The Framingham Heart Study. Circulation 1999;99(17): 2251-2254.
13. The Alcohol Use Disorders Identification Test [database on the Internet]. 2001.
14. Heatherton TF, Kozlowski LT, Frecker RC, Fagerstrom KO. The Fagerstrom Test for Nicotine Dependence: A revision of the Fagerstrom Tolerance Questionnaire. Br J Addict 1991;86(9): 1119-1127.
15. Bharathi AV, Sandhya N, Vaz M. The development & characteristics of a physical activity questionnaire for epidemiological studies in urban middle class Indians. Indian J Med Res 2000;111: 95-102.
16. Family Interview for Genetic Studies [database on the Internet]. 1992.
17. Udupa K, Sathyaprabha TN, Thirthalli J, Kishore KR, Lavekar GS, Raju TR, et al. Alteration of cardiac autonomic functions in patients with major depression: A study using heart rate variability measures. J Affect Disord 2007;100(1-3): 137-141.
18. Pradhan C, Yashavantha BS, Pal PK, Sathyaprabha TN. Spinocerebellar ataxias type 1, 2 and 3: A study of heart rate variability. Acta Neurol Scand 2008;117(5): 337-342.
19. Ewing DJ, editor. Autonomic failure: A textbook of clinical disorders of the autonomic nervous system. 3rd ed. Oxford (UK): Oxford University Press; 1992.
20. Erlenmeyer-Kimling L, Friedman D, Cornblatt B, Jacobsen R. Electrodermal recovery data on children of schizophrenic parents. Psychiatry Res 1985;14(2): 149-161.
21. Salzman LF, Klein RH. Habituation and conditioning of electrodermal responses in high risk children. Schizophr Bull 1978;4(2): 210-222.
22. Prentky RA, Salzman LF, Klein RH. Habituation and conditioning of skin conductance responses in children at risk. Schizophr Bull 1981;7(2): 281-291.
23. Hollister JM, Mednick SA, Brennan P, Cannon TD. Impaired autonomic nervous system-habituation in those at genetic risk for schizophrenia. Arch Gen Psychiatry 1994;51(7): 552-558.
24. Castro MN, Vigo DE, Weidema H, Fahrer RD, Chu EM, de Achaval D, et al. Heart rate variability response to mental arithmetic stress in patients with schizophrenia: Autonomic response to stress in schizophrenia. Schizophr Res 2008;99(1-3): 294-303.
25. Abhishekh HA, Nisarga P, Kisan R, Meghana A, Chandran S, Trichur Raju, et al. Influence of age and gender on autonomic regulation of heart. J Clin Monit Comput 2013;27(3): 259-264.
26. Wright IC, Rabe-Hesketh S, Woodruff PW, David AS, Murray RM, Bullmore ET. Meta-analysis of regional brain volumes in schizophrenia. Am J Psychiatry 2000;157(1): 16-25.
27. Lawrie SM, Abukmeil SS. Brain abnormality in schizophrenia. A systematic and quantitative review of volumetric magnetic resonance imaging studies. Br J Psychiatry 1998;172: 110-120.
28. Wong AH, Van Tol HH. Schizophrenia: From phenomenology to neurobiology. Neurosci Biobehav Rev 2003;27(3): 269-306.
29. Williams LM, Das P, Harris AW, Liddell BB, Brammer MJ, Olivieri G, et al. Dysregulation of arousal and amygdala-prefrontal systems in paranoid schizophrenia. Am J Psychiatry 2004;161(3): 480-489.
30. Flint J, Munafo MR. The endophenotype concept in psychiatric genetics. Psychol Med 2007;37(2): 163-180.
31. Gottesman II, Gould TD. The endophenotype concept in psychiatry: Etymology and strategic intentions. Am J Psychiatry 2003;160(4): 636-645.
32. Berger S, Schulz S, Kletta C, Voss A, Bar KJ. Autonomic modulation in healthy first-degree relatives of patients with major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry 2011;35(7): 1723-1728.