-
1
-
-
0028201742
-
Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 protooncogene
-
van der Lugt NM, Domen J, Linders K, et al. Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 protooncogene. Genes Dev. 1994;8(7):757-769.
-
(1994)
Genes Dev
, vol.8
, Issue.7
, pp. 757-769
-
-
Van Der Lugt, N.M.1
Domen, J.2
Linders, K.3
-
2
-
-
0037673984
-
Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
-
Lessard J, Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature. 2003;423(6937):255-260.
-
(2003)
Nature
, vol.423
, Issue.6937
, pp. 255-260
-
-
Lessard, J.1
Sauvageau, G.2
-
3
-
-
0038349957
-
Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
-
Park I-K, Qian D, Kiel M, et al. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature. 2003;423(6937):302-305.
-
(2003)
Nature
, vol.423
, Issue.6937
, pp. 302-305
-
-
Park, I.-K.1
Qian, D.2
Kiel, M.3
-
4
-
-
0033552813
-
The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
-
Jacobs JJ, Kieboom K, Marino S, DePinho RA, van Lohuizen M. The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature. 1999;397(6715):164-168.
-
(1999)
Nature
, vol.397
, Issue.6715
, pp. 164-168
-
-
Jacobs, J.J.1
Kieboom, K.2
Marino, S.3
DePinho, R.A.4
Van Lohuizen, M.5
-
5
-
-
10344258563
-
Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1
-
Iwama A, Oguro H, Negishi M, et al. Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. Immunity. 2004;21(6):843-851.
-
(2004)
Immunity
, vol.21
, Issue.6
, pp. 843-851
-
-
Iwama, A.1
Oguro, H.2
Negishi, M.3
-
6
-
-
22344449361
-
Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways
-
Molofsky AV, He S, Bydon M, Morrison SJ, Pardal R. Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways. Genes Dev. 2005;19(12):1432-1437.
-
(2005)
Genes Dev
, vol.19
, Issue.12
, pp. 1432-1437
-
-
Molofsky, A.V.1
He, S.2
Bydon, M.3
Morrison, S.J.4
Pardal, R.5
-
7
-
-
20544453888
-
Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice
-
Bruggeman SWM, Valk-Lingbeek ME, van der Stoop PP, et al. Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice. Genes Dev. 2005;19(12):1438-1443.
-
(2005)
Genes Dev
, vol.19
, Issue.12
, pp. 1438-1443
-
-
Bruggeman, S.W.M.1
Valk-Lingbeek, M.E.2
Van Der Stoop, P.P.3
-
8
-
-
33746626042
-
E4F1: A novel candidate factor for mediating BMI1 function in primitive hematopoietic cells
-
Chagraoui J, Niessen SL, Lessard J, et al. E4F1: a novel candidate factor for mediating BMI1 function in primitive hematopoietic cells. Genes Dev. 2006;20(15):2110-2120.
-
(2006)
Genes Dev
, vol.20
, Issue.15
, pp. 2110-2120
-
-
Chagraoui, J.1
Niessen, S.L.2
Lessard, J.3
-
9
-
-
33749350639
-
Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice
-
Oguro H, Iwama A, Morita Y, Kamijo T, van Lohuizen M, Nakauchi H. Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice. J Exp Med. 2006;203(10):2247-2253.
-
(2006)
J Exp Med
, vol.203
, Issue.10
, pp. 2247-2253
-
-
Oguro, H.1
Iwama, A.2
Morita, Y.3
Kamijo, T.4
Van Lohuizen, M.5
Nakauchi, H.6
-
10
-
-
43449084346
-
Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/-multipotent progenitors
-
Akala OO, Park I-K, Qian D, Pihalja M, Becker MW, Clarke MF. Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/-multipotent progenitors. Nature. 2008;453(7192):228-232.
-
(2008)
Nature
, vol.453
, Issue.7192
, pp. 228-232
-
-
Akala, O.O.1
Park, I.-K.2
Qian, D.3
Pihalja, M.4
Becker, M.W.5
Clarke, M.F.6
-
11
-
-
67349156082
-
Bmi1 regulates mitochondrial function and the DNA damage response pathway
-
Liu J, Cao L, Chen J, et al. Bmi1 regulates mitochondrial function and the DNA damage response pathway. Nature. 2009;459(7245):387-392.
-
(2009)
Nature
, vol.459
, Issue.7245
, pp. 387-392
-
-
Liu, J.1
Cao, L.2
Chen, J.3
-
12
-
-
79955076992
-
An anticlastogenic function for the Polycomb Group gene Bmi1
-
Chagraoui J, Hébert J, Girard S, Sauvageau G. An anticlastogenic function for the Polycomb Group gene Bmi1. Proc Natl Acad Sci USA. 2011;108(13):5284-5289.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.13
, pp. 5284-5289
-
-
Chagraoui, J.1
Hébert, J.2
Girard, S.3
Sauvageau, G.4
-
13
-
-
64249099616
-
A functional screen to identify novel effectors of hematopoietic stem cell activity
-
Deneault E, Cellot S, Faubert A, et al. A functional screen to identify novel effectors of hematopoietic stem cell activity. Cell. 2009;137(2):369-379.
-
(2009)
Cell
, vol.137
, Issue.2
, pp. 369-379
-
-
Deneault, E.1
Cellot, S.2
Faubert, A.3
-
14
-
-
77956449328
-
An RNAi screen identifies Msi2 and Prox1 as having opposite roles in the regulation of hematopoietic stem cell activity
-
Hope KJ, Cellot S, Ting SB, et al. An RNAi screen identifies Msi2 and Prox1 as having opposite roles in the regulation of hematopoietic stem cell activity. Cell Stem Cell. 2010;7(1):101-113.
-
(2010)
Cell Stem Cell
, vol.7
, Issue.1
, pp. 101-113
-
-
Hope, K.J.1
Cellot, S.2
Ting, S.B.3
-
15
-
-
0037396675
-
The competitive nature of HOXB4-transduced HSC is limited by PBX1: The generation of ultra-competitive stem cells retaining full differentiation potential
-
Krosl J, Beslu N, Mayotte N, Humphries RK, Sauvageau G. The competitive nature of HOXB4-transduced HSC is limited by PBX1: the generation of ultra-competitive stem cells retaining full differentiation potential. Immunity. 2003;18(4):561-571.
-
(2003)
Immunity
, vol.18
, Issue.4
, pp. 561-571
-
-
Krosl, J.1
Beslu, N.2
Mayotte, N.3
Humphries, R.K.4
Sauvageau, G.5
-
16
-
-
77956222562
-
Polycomb group proteins: Multi-faceted regulators of somatic stem cells and cancer
-
Sauvageau M, Sauvageau G. Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer. Cell Stem Cell. 2010;7(3):299-313.
-
(2010)
Cell Stem Cell
, vol.7
, Issue.3
, pp. 299-313
-
-
Sauvageau, M.1
Sauvageau, G.2
-
17
-
-
84888068789
-
RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity
-
Cellot S, Hope KJ, Chagraoui J, et al. RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity. Blood. 2013;122(9):1545-1555.
-
(2013)
Blood
, vol.122
, Issue.9
, pp. 1545-1555
-
-
Cellot, S.1
Hope, K.J.2
Chagraoui, J.3
-
18
-
-
84897954369
-
Identification of small molecules that support human leukemia stem cell activity ex vivo
-
Pabst C, Krosl J, Fares I, et al. Identification of small molecules that support human leukemia stem cell activity ex vivo. Nat Methods. 2014;11(4):436-442.
-
(2014)
Nat Methods
, vol.11
, Issue.4
, pp. 436-442
-
-
Pabst, C.1
Krosl, J.2
Fares, I.3
-
19
-
-
78751483481
-
RNA-seq analysis of 2 closely related leukemia clones that differ in their self-renewal capacity
-
Wilhelm BT, Briau M, Austin P, et al. RNA-seq analysis of 2 closely related leukemia clones that differ in their self-renewal capacity. Blood. 2011;117(2):e27-e38.
-
(2011)
Blood
, vol.117
, Issue.2
, pp. e27-e38
-
-
Wilhelm, B.T.1
Briau, M.2
Austin, P.3
-
20
-
-
0029155706
-
Inducible gene targeting in mice
-
Kühn R, Schwenk F, Aguet M, Rajewsky K. Inducible gene targeting in mice. Science. 1995;269(5229):1427-1429.
-
(1995)
Science
, vol.269
, Issue.5229
, pp. 1427-1429
-
-
Kühn, R.1
Schwenk, F.2
Aguet, M.3
Rajewsky, K.4
-
21
-
-
3042856262
-
Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus
-
Srinivas S, Watanabe T, Lin CS, et al. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol. 2001;1:4.
-
(2001)
BMC Dev Biol
, vol.1
, pp. 4
-
-
Srinivas, S.1
Watanabe, T.2
Lin, C.S.3
-
22
-
-
84863011309
-
PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes
-
Gao Z, Zhang J, Bonasio R, et al. PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes. Mol Cell. 2012;45(3):344-356.
-
(2012)
Mol Cell
, vol.45
, Issue.3
, pp. 344-356
-
-
Gao, Z.1
Zhang, J.2
Bonasio, R.3
|