Transplantation between monozygotic twins: How identical are they?

Transplantation

Volumn 98, Issue 5, 2014, Pages 485-489

  Day, Elizabeth ^a   Kearns, Patrick K ^a   Taylor, Craig J ^b,c   Bradley, J Andrew ^c,d  

^a SOUTHERN GENERAL HOSPITAL   (United Kingdom)

^b CAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^c NIHR Cambridge Comprehensive Biomedical Research Centre   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Genetic; Transplantation; Twin

Indexed keywords

CALCINEURIN INHIBITOR; CYCLOPHOSPHAMIDE; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; STEROID;

ARTICLE; BREAST RECONSTRUCTION; DOSE RESPONSE; EPIGENETICS; GRAFT FAILURE; GRAFT REJECTION; GRAFT SURVIVAL; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INSULIN DEPENDENT DIABETES MELLITUS; INTESTINE TRANSPLANTATION; KIDNEY FAILURE; KIDNEY PANCREAS TRANSPLANTATION; LIVER CIRRHOSIS; LIVER TRANSPLANTATION; LIVING DONOR; LOW DRUG DOSE; MONOZYGOTIC TWINS; MOSAICISM; NECROTIZING ARTERITIS; ORGAN DONOR; ORGAN TRANSPLANTATION; PHENOTYPE; PRIORITY JOURNAL; TWIN DISCORDANCE; TWIN ZYGOSITY; CHIMERA; GENETIC EPIGENESIS; GENETICS; IMMUNOLOGY; KIDNEY TRANSPLANTATION;

CHIMERISM; EPIGENESIS, GENETIC; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; MOSAICISM; PHENOTYPE; TWINS, MONOZYGOTIC;

EID: 84907598661     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0000000000000274     Document Type: Article

References (48)

1. Merrill JP, Murray JE, Harrison JH, et al. Successful homotransplantation of the human kidney between identical twins. J Am Med Assoc 1956; 160: 277.
2. Krishnan N, Buchanan PM, Dzebisashvili N, et al. Monozygotic transplantation: Concerns and opportunities. Am J Transplant 2008; 8: 2343.
3. Gumprich M, Woeste G, Kohlhaw K, et al. Living related kidney transplantation between identical twins. Transplant Proc 2002; 34: 2205.
4. Kim YK, Yoon HE, Kim SH, et al. Long-term follow-up of three identical twin transplant recipients without maintenance immunosuppressive therapy. Nephrology (Carlton) 2008; 13: 447.
5. Kessaris N, Mukherjee D, Chandak P, et al. Renal transplantation in identical twins in United States and United Kingdom. Transplantation 2008; 86: 1572.
6. Dziewanowski K, Drozd R, Chojnowska A, et al. Kidney transplantation among identical twins: Therapeutic dilemmas. BMJ Case Rep 2011; 2011.
7. Czyz W, Morahan JM, Ebers GC, et al. Genetic, environmental and stochastic factors in monozygotic twin discordance with a focus on epigenetic differences. BMC Med 2012; 10: 93.
8. Bell JT, Spector TD. A twin approach to unraveling epigenetics. Trends Genet 2011; 27: 116.
9. Solomon BD, Hadley DW, Pineda-Alvarez DE, et al. Incidental medical information in whole-exome sequencing. Pediatrics 2012; 129: E1605.
10. Zwijnenburg PJ, Meijers-Heijboer H, Boomsma DI. Identical but not the same: The value of discordant monozygotic twins in genetic research. Am J Med Genet B Neuropsychiatr Genet 2010; 153B: 1134.
11. Touma M, Joshi M, Connolly MC, et al. Whole genome sequencing identifies SCN2A mutation in monozygotic twins with Ohtahara syndrome and unique neuropathologic findings. Epilepsia 2013; 54: e81.
12. Bruder CE, Piotrowski A, Gijsbers AA, et al. Phenotypically concordant and discordant monozygotic twins display different DNA copynumber-variation profiles. Am J Hum Genet 2008; 82: 763.
13. West PM, Love DR, Stapleton PM, et al. Paternal uniparental disomy in monozygotic twins discordant for hemihypertrophy. J Med Genet 2003; 40: 223.
14. Fraga MF, Ballestar E, Paz MF, et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA 2005; 102: 10604.
15. Talens RP, Christensen K, Putter H, et al. Epigenetic variation during the adult lifespan: cross-sectional and longitudinal data on monozygotic twin pairs. Aging Cell 2012; 11: 694.
16. Gordon L, Joo JH, Andronikos R, et al. Expression discordance of monozygotic twins at birth: effect of intrauterine environment and a possible mechanism for fetal programming. Epigenetics 2011; 6: 579.
17. Forsberg LA, Absher D, Dumanski JP. Non-heritable genetics of human disease: spotlight on post-zygotic genetic variation acquired during lifetime. J Med Genet 2013; 50: 1.
18. Khosrotehrani K, Johnson KL, Cha DH, et al. Transfer of fetal cells with multilineage potential to maternal tissue. JAMA 2004; 292: 75.
19. Bianchi DW, Zickwolf GK, Weil GJ, et al. Male fetal progenitor cells persist in maternal blood for as long as 27 years postpartum. Proc Natl Acad Sci USA 1996; 93: 705.
20. Nelson JL. The otherness of self: microchimerism in health and disease. Trends Immunol 2012; 33: 421.
21. Stevens AM, McDonnell WM, Mullarkey ME, et al. Liver biopsies from human females contain male hepatocytes in the absence of transplantation. Lab Invest 2004; 84: 1603.
22. Bayes-Genis A, Bellosillo B, de la Calle O, et al. Identification of male cardiomyocytes of extracardiac origin in the hearts of women with male progeny: male fetal cell microchimerism of the heart. J Heart Lung Transplant 2005; 24: 2179.
23. Lee TH, Donegan E, Slichter S, et al. Transient increase in circulating donor leukocytes after allogeneic transfusions in immunocompetent recipients compatible with donor cell proliferation. Blood 1995; 85: 1207.
24. Starzl TE, Demetris AJ, Trucco M, et al. Chimerism after liver transplantation for type IV glycogen storage disease and type 1 Gaucher's disease. N Engl J Med 1993; 328: 745.
25. O'Huallachain M, Karczewski KJ, Weissman SM, et al. Extensive genetic variation in somatic human tissues. Proc Natl Acad Sci USA 2012; 109: 18018.
26. Moayyeri A, Hammond CJ, Hart DJ, et al. The UK Adult Twin Registry (TwinsUK Resource). Twin Res Hum Genet 2013; 16: 144.
27. Machin G. Non-identical monozygotic twins, intermediate twin types, zygosity testing, and the non-random nature of monozygotic twinning: a review. Am J Med Genet C Semin Med Genet 2009; 151C: 110.
28. Montgomery GW, Zhu G, Hottenga JJ, et al. HLA and genomewide allele sharing in dizygotic twins. Am J Hum Genet 2006; 79: 1052.
29. Baranzini SE,Mudge J, van Velkinburgh JC, et al. Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis. Nature 2010; 464: 1351.
30. Breckpot J, Thienpont B, Gewillig M, et al. Differences in copy number variation between discordant monozygotic twins as a model for exploring chromosomal mosaicism in congenital heart defects. Mol Syndromol 2012; 2: 81.
31. Worthington J, Silman AJ. Genetic control of autoimmunity, lessons from twin studies. Clin Exp Immunol 1995; 101: 390.
32. Gregersen PK. Discordance for autoimmunity in monozygotic twins. Are "identical" twins really identical? Arthritis Rheum 1993; 36: 1185.
33. Zielinski A, Nazarewski S, Bogetti D, et al. Simultaneous pancreaskidney transplant from living related donor: a single-center experience. Transplantation 2003; 76: 547.
34. Benedetti E, Dunn T, Massad MG, et al. Successful living related simultaneous pancreas-kidney transplant between identical twins. Transplantation 1999; 67: 915.
35. Liu LU, Schiano TD, Min AD, et al. Syngeneic living-donor liver transplantation without the use of immunosuppression. Gastroenterology 2002; 123: 1341.
36. Yoshizawa A, Takada Y, Fujimoto Y, et al. Liver transplantation from an identical twin without immunosuppression, with early recurrence of hepatitis C. Am J Transplant 2006; 6: 2812.
37. Sugawara Y, Ohtsuka H, Kaneko J, et al. Successful treatment of hepatitis C virus after liver transplantation from an identical twin. Transplantation 2002; 73: 1850.
38. Schena S, Testa G, Setty S, et al. Successful identical-twin living donor small bowel transplant for necrotizing enterovasculitis secondary to Churg-Strauss syndrome. Transpl Int 2006; 19: 594.
39. Berney T, Genton L, Buhler LH, et al. Five-year follow-up after pediatric living related small bowel transplantation between two monozygotic twins. Transplant Proc 2004; 36: 316.
40. Genton L, Raguso CA, Berney T, et al. Four year nutritional follow up after living related small bowel transplantation between monozygotic twins. Gut 2003; 52: 659.
41. Silber SJ, DeRosa M, Pineda J, et al. A series of monozygotic twins discordant for ovarian failure: ovary transplantation (cortical versus microvascular) and cryopreservation. Hum Reprod 2008; 23: 1531.
42. Hazani R, Coots BK, Buntic RF, et al. Bilateral breast reconstruction: the simultaneous use of autogenous tissue and identical twin isograft. Ann Plast Surg 2009; 63: 496.
43. Cheigh JS, Chami J, Stenzel KH, et al. Renal transplantation between HLA identical siblings. Comparison with transplants from HLA semiidentical related donors. N Engl J Med 1977; 296: 1030.
44. Matzinger P. The danger model: a renewed sense of self. Science 2002; 296: 301.
45. Nickerson PW, Rush DN. Antibodies beyond HLA. Am J Transplant 2013; 13: 831.
46. Bramstedt KA. Living donor transplantation between twins: guidance for Donor Advocate Teams. Clin Transplant 2007; 21: 144.
47. de Mattos AM, Bennett WM, Barry JM, et al. HLA-identical sibling renal transplantationVa 21-yr single-center experience. Clin Transplant 1999; 13: 158.
48. Shimmura H, Tanabe K, Ishida H, et al. Long-term results of living kidney transplantation from HLA-identical sibling donors under calcineurin inhibitor immunosuppression. Int J Urol 2006; 13: 502.