메뉴 건너뛰기




Volumn 83, Issue 4, 2014, Pages 839-849

The Crystal Structure of Netrin-1 in Complex with DCC Reveals the Bifunctionality of Netrin-1 As a Guidance Cue

Author keywords

[No Author keywords available]

Indexed keywords

DELETED IN COLORECTAL CANCER RECEPTOR; MEMBRANE RECEPTOR; NETRIN 1; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; DCC PROTEIN, HUMAN; NERVE GROWTH FACTOR; NETRIN RECEPTORS; NETRIN-1; PROTEIN BINDING; TUMOR SUPPRESSOR PROTEIN; DCC RECEPTOR; NETRIN RECEPTOR; PROTEIN UNC5A; RECEPTOR PROTEIN; SULFATE; TRANSCRIPTION FACTOR;

EID: 84907597938     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2014.07.010     Document Type: Article
Times cited : (90)

References (48)
  • 2
    • 50849109798 scopus 로고    scopus 로고
    • Rational vector design and multi-pathway modulation of HEK 293E cells yield recombinant antibody titers exceeding 1 g/l by transient transfection under serum-free conditions
    • Backliwal G., Hildinger M., Chenuet S., Wulhfard S., De Jesus M., Wurm F.M. Rational vector design and multi-pathway modulation of HEK 293E cells yield recombinant antibody titers exceeding 1 g/l by transient transfection under serum-free conditions. Nucleic Acids Res. 2008, 36:e96.
    • (2008) Nucleic Acids Res. , vol.36
    • Backliwal, G.1    Hildinger, M.2    Chenuet, S.3    Wulhfard, S.4    De Jesus, M.5    Wurm, F.M.6
  • 4
    • 84883894803 scopus 로고    scopus 로고
    • Optimization of protein purification and characterization using Thermofluor screens
    • Boivin S., Kozak S., Meijers R. Optimization of protein purification and characterization using Thermofluor screens. Protein Expr. Purif. 2013, 91:192-206.
    • (2013) Protein Expr. Purif. , vol.91 , pp. 192-206
    • Boivin, S.1    Kozak, S.2    Meijers, R.3
  • 5
  • 7
    • 84871741824 scopus 로고    scopus 로고
    • Crystal structures of the network-forming short-arm tips of the laminin β1 and γ1 chains
    • Carafoli F., Hussain S.-A., Hohenester E. Crystal structures of the network-forming short-arm tips of the laminin β1 and γ1 chains. PLoS ONE 2012, 7:e42473.
    • (2012) PLoS ONE , vol.7
    • Carafoli, F.1    Hussain, S.-A.2    Hohenester, E.3
  • 9
    • 84875609239 scopus 로고    scopus 로고
    • N-terminal horseshoe conformation of DCC is functionally required for axon guidance and might be shared by other neural receptors
    • Chen Q., Sun X., Zhou X.H., Liu J.H., Wu J., Zhang Y., Wang J.H. N-terminal horseshoe conformation of DCC is functionally required for axon guidance and might be shared by other neural receptors. J.Cell Sci. 2013, 126:186-195.
    • (2013) J.Cell Sci. , vol.126 , pp. 186-195
    • Chen, Q.1    Sun, X.2    Zhou, X.H.3    Liu, J.H.4    Wu, J.5    Zhang, Y.6    Wang, J.H.7
  • 10
    • 0028916599 scopus 로고
    • A hot spot of binding energy in a hormone-receptor interface
    • Clackson T., Wells J.A. A hot spot of binding energy in a hormone-receptor interface. Science 1995, 267:383-386.
    • (1995) Science , vol.267 , pp. 383-386
    • Clackson, T.1    Wells, J.A.2
  • 11
    • 0029065329 scopus 로고
    • The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons
    • Colamarino S.A., Tessier-Lavigne M. The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons. Cell 1995, 81:621-629.
    • (1995) Cell , vol.81 , pp. 621-629
    • Colamarino, S.A.1    Tessier-Lavigne, M.2
  • 12
    • 0037032812 scopus 로고    scopus 로고
    • Molecular mechanisms of axon guidance
    • Dickson B.J. Molecular mechanisms of axon guidance. Science 2002, 298:1959-1964.
    • (2002) Science , vol.298 , pp. 1959-1964
    • Dickson, B.J.1
  • 14
    • 62649139615 scopus 로고    scopus 로고
    • DAMMIF, a program for rapid ab-initio shape determination in small-angle scattering
    • Franke D., Svergun D.I. DAMMIF, a program for rapid ab-initio shape determination in small-angle scattering. J.Appl. Cryst. 2009, 42:342-346.
    • (2009) J.Appl. Cryst. , vol.42 , pp. 342-346
    • Franke, D.1    Svergun, D.I.2
  • 16
    • 0042357532 scopus 로고    scopus 로고
    • Netrin binds discrete subdomains of DCC and UNC5 and mediates interactions between DCC and heparin
    • Geisbrecht B.V., Dowd K.A., Barfield R.W., Longo P.A., Leahy D.J. Netrin binds discrete subdomains of DCC and UNC5 and mediates interactions between DCC and heparin. J.Biol. Chem. 2003, 278:32561-32568.
    • (2003) J.Biol. Chem. , vol.278 , pp. 32561-32568
    • Geisbrecht, B.V.1    Dowd, K.A.2    Barfield, R.W.3    Longo, P.A.4    Leahy, D.J.5
  • 17
    • 0033603256 scopus 로고    scopus 로고
    • A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion
    • Hong K., Hinck L., Nishiyama M., Poo M.M., Tessier-Lavigne M., Stein E. A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion. Cell 1999, 97:927-941.
    • (1999) Cell , vol.97 , pp. 927-941
    • Hong, K.1    Hinck, L.2    Nishiyama, M.3    Poo, M.M.4    Tessier-Lavigne, M.5    Stein, E.6
  • 18
    • 0034610795 scopus 로고    scopus 로고
    • Calcium signalling in the guidance of nerve growth by netrin-1
    • Hong K., Nishiyama M., Henley J., Tessier-Lavigne M., Poo M. Calcium signalling in the guidance of nerve growth by netrin-1. Nature 2000, 403:93-98.
    • (2000) Nature , vol.403 , pp. 93-98
    • Hong, K.1    Nishiyama, M.2    Henley, J.3    Tessier-Lavigne, M.4    Poo, M.5
  • 20
    • 0028061313 scopus 로고
    • Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord
    • Kennedy T.E., Serafini T., de la Torre J.R., Tessier-Lavigne M. Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord. Cell 1994, 78:425-435.
    • (1994) Cell , vol.78 , pp. 425-435
    • Kennedy, T.E.1    Serafini, T.2    de la Torre, J.R.3    Tessier-Lavigne, M.4
  • 21
    • 0034676061 scopus 로고    scopus 로고
    • A novel member of the netrin family, beta-netrin, shares homology with the beta chain of laminin: identification, expression, and functional characterization
    • Koch M., Murrell J.R., Hunter D.D., Olson P.F., Jin W., Keene D.R., Brunken W.J., Burgeson R.E. A novel member of the netrin family, beta-netrin, shares homology with the beta chain of laminin: identification, expression, and functional characterization. J.Cell Biol. 2000, 151:221-234.
    • (2000) J.Cell Biol. , vol.151 , pp. 221-234
    • Koch, M.1    Murrell, J.R.2    Hunter, D.D.3    Olson, P.F.4    Jin, W.5    Keene, D.R.6    Brunken, W.J.7    Burgeson, R.E.8
  • 24
    • 84857411679 scopus 로고    scopus 로고
    • Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours
    • Krimpenfort P., Song J.-Y., Proost N., Zevenhoven J., Jonkers J., Berns A. Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours. Nature 2012, 482:538-541.
    • (2012) Nature , vol.482 , pp. 538-541
    • Krimpenfort, P.1    Song, J.-Y.2    Proost, N.3    Zevenhoven, J.4    Jonkers, J.5    Berns, A.6
  • 25
    • 79956314865 scopus 로고    scopus 로고
    • Netrins: versatile extracellular cues with diverse functions
    • Lai Wing Sun K., Correia J.P., Kennedy T.E. Netrins: versatile extracellular cues with diverse functions. Development 2011, 138:2153-2169.
    • (2011) Development , vol.138 , pp. 2153-2169
    • Lai Wing Sun, K.1    Correia, J.P.2    Kennedy, T.E.3
  • 26
    • 37549051660 scopus 로고    scopus 로고
    • Netrin signal transduction and the guanine nucleotide exchange factor DOCK180 in attractive signaling
    • Li X., Gao X., Liu G., Xiong W., Wu J., Rao Y. Netrin signal transduction and the guanine nucleotide exchange factor DOCK180 in attractive signaling. Nat. Neurosci. 2008, 11:28-35.
    • (2008) Nat. Neurosci. , vol.11 , pp. 28-35
    • Li, X.1    Gao, X.2    Liu, G.3    Xiong, W.4    Wu, J.5    Rao, Y.6
  • 27
    • 0037104797 scopus 로고    scopus 로고
    • Identification of domains of netrin UNC-6 that mediate attractive and repulsive guidance and responses from cells and growth cones
    • Lim Y.S., Wadsworth W.G. Identification of domains of netrin UNC-6 that mediate attractive and repulsive guidance and responses from cells and growth cones. J.Neurosci. 2002, 22:7080-7087.
    • (2002) J.Neurosci. , vol.22 , pp. 7080-7087
    • Lim, Y.S.1    Wadsworth, W.G.2
  • 30
    • 45449083263 scopus 로고    scopus 로고
    • DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1
    • Ly A., Nikolaev A., Suresh G., Zheng Y., Tessier-Lavigne M., Stein E. DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1. Cell 2008, 133:1241-1254.
    • (2008) Cell , vol.133 , pp. 1241-1254
    • Ly, A.1    Nikolaev, A.2    Suresh, G.3    Zheng, Y.4    Tessier-Lavigne, M.5    Stein, E.6
  • 34
    • 84866982807 scopus 로고    scopus 로고
    • Less than 5 Netrin-1 molecules initiate attraction but 200 Sema3A molecules are necessary for repulsion
    • Pinato G., Cojoc D., Lien L.T., Ansuini A., Ban J., D'Este E., Torre V. Less than 5 Netrin-1 molecules initiate attraction but 200 Sema3A molecules are necessary for repulsion. Sci Rep 2012, 2:675.
    • (2012) Sci Rep , vol.2 , pp. 675
    • Pinato, G.1    Cojoc, D.2    Lien, L.T.3    Ansuini, A.4    Ban, J.5    D'Este, E.6    Torre, V.7
  • 36
    • 79851482960 scopus 로고    scopus 로고
    • Pattern of invasion of the embryonic mouse spinal cord by microglial cells at the time of the onset of functional neuronal networks
    • Rigato C., Buckinx R., Le-Corronc H., Rigo J.M., Legendre P. Pattern of invasion of the embryonic mouse spinal cord by microglial cells at the time of the onset of functional neuronal networks. Glia 2011, 59:675-695.
    • (2011) Glia , vol.59 , pp. 675-695
    • Rigato, C.1    Buckinx, R.2    Le-Corronc, H.3    Rigo, J.M.4    Legendre, P.5
  • 38
    • 0028138219 scopus 로고
    • The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6
    • Serafini T., Kennedy T.E., Galko M.J., Mirzayan C., Jessell T.M., Tessier-Lavigne M. The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6. Cell 1994, 78:409-424.
    • (1994) Cell , vol.78 , pp. 409-424
    • Serafini, T.1    Kennedy, T.E.2    Galko, M.J.3    Mirzayan, C.4    Jessell, T.M.5    Tessier-Lavigne, M.6
  • 39
    • 33847030646 scopus 로고    scopus 로고
    • Profiling the sulfation specificities of glycosaminoglycan interactions with growth factors and chemotactic proteins using microarrays
    • Shipp E.L., Hsieh-Wilson L.C. Profiling the sulfation specificities of glycosaminoglycan interactions with growth factors and chemotactic proteins using microarrays. Chem. Biol. 2007, 14:195-208.
    • (2007) Chem. Biol. , vol.14 , pp. 195-208
    • Shipp, E.L.1    Hsieh-Wilson, L.C.2
  • 40
    • 0035831295 scopus 로고    scopus 로고
    • Binding of DCC by netrin-1 to mediate axon guidance independent of adenosine A2B receptor activation
    • Stein E., Zou Y., Poo M., Tessier-Lavigne M. Binding of DCC by netrin-1 to mediate axon guidance independent of adenosine A2B receptor activation. Science 2001, 291:1976-1982.
    • (2001) Science , vol.291 , pp. 1976-1982
    • Stein, E.1    Zou, Y.2    Poo, M.3    Tessier-Lavigne, M.4
  • 41
    • 0029185933 scopus 로고
    • CRYSOL - a Program to Evaluate X-ray Solution Scattering of Biological Macromolecules from Atomic Coordinates
    • Svergun D., Barberato C., Koch M.H.J. CRYSOL - a Program to Evaluate X-ray Solution Scattering of Biological Macromolecules from Atomic Coordinates. J.Appl. Cryst. 1995, 28:768-773.
    • (1995) J.Appl. Cryst. , vol.28 , pp. 768-773
    • Svergun, D.1    Barberato, C.2    Koch, M.H.J.3
  • 43
    • 0033564372 scopus 로고    scopus 로고
    • Netrin-3, a mouse homolog of human NTN2L, is highly expressed in sensory ganglia and shows differential binding to netrin receptors
    • Wang H., Copeland N.G., Gilbert D.J., Jenkins N.A., Tessier-Lavigne M. Netrin-3, a mouse homolog of human NTN2L, is highly expressed in sensory ganglia and shows differential binding to netrin receptors. J.Neurosci. 1999, 19:4938-4947.
    • (1999) J.Neurosci. , vol.19 , pp. 4938-4947
    • Wang, H.1    Copeland, N.G.2    Gilbert, D.J.3    Jenkins, N.A.4    Tessier-Lavigne, M.5
  • 44
    • 62549095266 scopus 로고    scopus 로고
    • Autoinhibition of UNC5b revealed by the cytoplasmic domain structure of the receptor
    • Wang R., Wei Z., Jin H., Wu H., Yu C., Wen W., Chan L.-N., Wen Z., Zhang M. Autoinhibition of UNC5b revealed by the cytoplasmic domain structure of the receptor. Mol. Cell 2009, 33:692-703.
    • (2009) Mol. Cell , vol.33 , pp. 692-703
    • Wang, R.1    Wei, Z.2    Jin, H.3    Wu, H.4    Yu, C.5    Wen, W.6    Chan, L.-N.7    Wen, Z.8    Zhang, M.9
  • 45
    • 33746875636 scopus 로고    scopus 로고
    • Neogenin interacts with RGMa and netrin-1 to guide axons within the embryonic vertebrate forebrain
    • Wilson N.H., Key B. Neogenin interacts with RGMa and netrin-1 to guide axons within the embryonic vertebrate forebrain. Dev. Biol. 2006, 296:485-498.
    • (2006) Dev. Biol. , vol.296 , pp. 485-498
    • Wilson, N.H.1    Key, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.