Activity-modulating monoclonal antibodies to the human serine protease HtrA3 provide novel insights into regulating HtrA proteolytic activities

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Singh, Harmeet ^a,b   Nero, Tracy L ^c   Wang, Yao ^a,b   Parker, Michael W ^c,d   Nie, Guiying ^a,b  

^a HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 10H10; MONOCLONAL ANTIBODY 3E6; MONOCLONAL ANTIBODY 6G6; MONOCLONAL ANTIBODY 9C9; PERTUZUMAB; SERINE PROTEASE HTRA3; SERINE PROTEINASE; UNCLASSIFIED DRUG; HTRA3 PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ARTICLE; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SUBSTRATE; EPITOPE MAPPING; HUMAN; HUMAN CELL; IN VIVO STUDY; NUCLEOTIDE SEQUENCE; PDZ DOMAIN; PHARMACOLOGICAL BLOCKING; PROTEIN DEGRADATION; PROTEIN DOMAIN; TROPHOBLAST; X RAY CRYSTALLOGRAPHY; CELL LINE; CELL MOTION; DRUG EFFECTS; FEMALE; IMMUNOLOGY; PHYSIOLOGY; PREGNANCY;

ANTIBODIES, MONOCLONAL; CELL LINE; CELL MOVEMENT; EPITOPES; FEMALE; HUMANS; PREGNANCY; SERINE ENDOPEPTIDASES; TROPHOBLASTS;

EID: 84907587249     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108235     Document Type: Article

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