Early or late IL-10 blockade enhances Th1 and Th17 effector responses and promotes fungal clearance in mice with cryptococcal lung infection

Journal of Immunology

Volumn 193, Issue 8, 2014, Pages 4107-4116

  Murdock, Benjamin J ^a,b   Teitz Tennenbaum, Seagal ^a,b   Chen, Gwo Hsiao ^a,b   Dils, Anthony J ^a,b   Malachowski, Antoni N ^a,b   Curtis, Jeffrey L ^a,b,c   Olszewski, Michal A ^a,b,c   Osterholzer, John J ^a,b,c  

^a VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; CD11B ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR ANTIBODY; UNCLASSIFIED DRUG; BLOCKING ANTIBODY; IL10 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BRAIN INFECTION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL COUNT; CELLULAR IMMUNITY; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; CRYPTOCOCCUS NEOFORMANS STRAIN 52D; DENDRITIC CELL; FUNGAL BURDEN; IMMUNOMODULATION; IMMUNOPHENOTYPING; INFECTION CONTROL; LEUKOCYTE; LUNG ALVEOLUS MACROPHAGE; MOUSE; MURINE MODEL; NONHUMAN; PATHOGEN CLEARANCE; PATHOGEN LOAD; PROTEIN EXPRESSION; PULMONARY CRYPTOCOCCOSIS; TH1 CELL; TH17 CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CRYPTOCOCCOSIS; GENETICS; IMMUNOLOGY; LUNG MYCOSIS; LYMPHOCYTE COUNT; MACROPHAGE; MICROBIOLOGY;

ANIMALS; ANTIBODIES, BLOCKING; B-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; DENDRITIC CELLS; IMMUNOPHENOTYPING; INTERLEUKIN-10; LUNG DISEASES, FUNGAL; LYMPHOCYTE COUNT; MACROPHAGES; MICE; MICE, INBRED C57BL; TH1 CELLS; TH17 CELLS;

EID: 84907546217     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400650     Document Type: Article

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