Prognostic significance of systemic inflammation-based lymphocyte-monocyte ratio in patients with lung cancer: Based on a large cohort study

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Hu, Pingping ^a   Shen, Hongchang ^a   Wang, Guanghui ^a   Zhang, Ping ^a   Liu, Qi ^a   Du, Jiajun ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BLOOD CELL RATIO; CANCER MORTALITY; CANCER PATIENT; CANCER PROGNOSIS; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; COHORT ANALYSIS; DISEASE ASSOCIATION; DISEASE FREE SURVIVAL; FEMALE; GROUPS BY AGE; HIGH RISK PATIENT; HUMAN; INFLAMMATION; LEUKOCYTE COUNT; LUNG CANCER; LYMPHOCYTE COUNT; LYMPHOCYTE MONOCYTE RATIO; MAJOR CLINICAL STUDY; MALE; MONOCYTE COUNT; NON SMALL CELL LUNG CANCER; OVERALL SURVIVAL; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; SMALL CELL LUNG CANCER; SMOKING; KAPLAN MEIER METHOD; LUNG TUMOR; METABOLISM; MIDDLE AGED; MONOCYTE; PATHOLOGY; PROGNOSIS; VERY ELDERLY; YOUNG ADULT;

TUMOR MARKER;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; COHORT STUDIES; FEMALE; HUMANS; INFLAMMATION; KAPLAN-MEIER ESTIMATE; LUNG NEOPLASMS; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; MONOCYTES; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 84907522215     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108062     Document Type: Article

References (33)

1. Dela Cruz CS, Tanoue LT, Matthay RA (2011) Lung cancer: epidemiology, etiology, and prevention. Clinics in chest medicine 32:605-644.
2. Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144:646-674.
3. McMillan DC, Canna K, McArdle CS (2003) Systemic inflammatory response predicts survival following curative resection of colorectal cancer. Br J Surg 90:215-219.
4. McMillan DC (2009) Systemic inflammation, nutritional status and survival in patients with cancer. Curr Opin Clin Nutr Metab Care 12:223-226.
5. Szkandera J, Gerger A, Liegl-Atzwanger B, Absenger G, Stotz M, et al. (2013) The lymphocyte/monocyte ratio predicts poor clinical outcome and improves the predictive accuracy in patients with soft tissue sarcomas. Int J Cancer.
6. Roxburgh CS, McMillan DC (2010) Role of systemic inflammatory response in predicting survival in patients with primary operable cancer. Future oncology 6:149-163.
7. Clarke S, Chua W, Moore M, Kao S, Phan V, et al. (2011) Use of inflammatory markers to guide cancer treatment. Clinical Pharmacology & Therapeutics 90.
8. Guthrie GJ, Charles KA, Roxburgh CS, Horgan PG, McMillan DC, et al. (2013) The systemic inflammation-based neutrophil-lymphocyte ratio: Experience in patients with cancer. Critical reviews in oncology/hematology 88:218-230.
9. Li YL, Pan YY, Jiao Y, Ning J, Fan YG, et al. (2014) Peripheral blood lymphocyte/monocyte ratio predicts outcome for patients with diffuse large B cell lymphoma after standard first-line regimens. Ann Hematol 93:617-626.
10. Porrata LF, Ristow K, Habermann TM, Witzig TE, Colgan JP, et al. (2012) Peripheral blood lymphocyte/monocyte ratio at diagnosis and survival in nodular lymphocyte-predominant Hodgkin lymphoma. Br J Haematol 157:321-330.
11. Porrata LF, Ristow K, Habermann TM, Ozsan N, Dogan A, et al. (2012) Absolute monocyte/lymphocyte count prognostic score is independent of immunohistochemically determined cell of origin in predicting survival in diffuse large B-cell lymphoma. Leuk Lymphoma 53:2159-2165.
12. Li J, Jiang R, Liu WS, Liu Q, Xu M, et al. (2013) A large cohort study reveals the association of elevated peripheral blood lymphocyte-to-monocyte ratio with favorable prognosis in nasopharyngeal carcinoma. PLoS One 8:e83069.
13. Goldstraw P, Crowley J, Chansky K, Giroux DJ, Groome PA, et al. (2007) The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours. J Thorac Oncol 2:706-714.
14. Cihan YB, Ozturk A, Mutlu H (2014) Relationship between prognosis and neutrophil: lymphocyte and platelet: lymphocyte ratios in patients with malignant pleural mesotheliomas. Asian Pac J Cancer Prev 15:2061-2067.
15. Walsh SR, Cook EJ, Goulder F, Justin TA, Keeling NJ (2005) Neutrophillymphocyte ratio as a prognostic factor in colorectal cancer. J Surg Oncol 91:181-184.
16. Li ZM, Huang JJ, Xia Y, Sun J, Huang Y, et al. (2012) Blood lymphocyte-tomonocyte ratio identifies high-risk patients in diffuse large B-cell lymphoma treated with R-CHOP. PLoS One 7:e41658.
17. Aoki K, Tabata S, Yonetani N, Matsushita A, Ishikawa T (2013) The prognostic impact of absolute lymphocyte and monocyte counts at diagnosis of diffuse large B-cell lymphoma in the rituximab era. Acta Haematol 130:242-246.
18. Koh YW, Kang HJ, Park C, Yoon DH, Kim S, et al. (2012) The ratio of the absolute lymphocyte count to the absolute monocyte count is associated with prognosis in Hodgkin's lymphoma: correlation with tumor-associated macrophages. Oncologist 17:871-880.
19. Landskron G, De la Fuente M, Thuwajit P, Thuwajit C, Hermoso MA (2014) Chronic Inflammation and Cytokines in the Tumor Microenvironment. J Immunol Res 2014:149185.
20. Balkwill F, Mantovani A (2001) Inflammation and cancer: back to Virchow? Lancet 357:539-545.
21. Bishara S, Griffin M, Cargill A, Bali A, Gore ME, et al. (2008) Pre-treatment white blood cell subtypes as prognostic indicators in ovarian cancer. Eur J Obstet Gynecol Reprod Biol 138:71-75.
22. Botta C, Barbieri V, Ciliberto D, Rossi A, Rocco D, et al. (2013) Systemic inflammatory status at baseline predicts bevacizumab benefit in advanced nonsmall cell lung cancer patients. Cancer Biol Ther 14:469-475.
23. Haruki K, Shiba H, Fujiwara Y, Furukawa K, Wakiyama S, et al. (2012) Perioperative change in peripheral blood monocyte count may predict prognosis in patients with colorectal liver metastasis after hepatic resection. J Surg Oncol 106:31-35.
24. Lee YY, Choi CH, Sung CO, Do IG, Huh S, et al. (2012) Prognostic value of pre-treatment circulating monocyte count in patients with cervical cancer: comparison with SCC-Ag level. Gynecol Oncol 124:92-97.
25. Stotz M, Pichler M, Absenger G, Szkandera J, Arminger F, et al. (2014) The preoperative lymphocyte to monocyte ratio predicts clinical outcome in patients with stage III colon cancer. Br J Cancer 110:435-440.
26. Mantovani A, Bottazzi B, Colotta F, Sozzani S, Ruco L (1992) The origin and function of tumor-associated macrophages. Immunol Today 13:265-270.
27. Galdiero MR, Garlanda C, Jaillon S, Marone G, Mantovani A (2013) Tumor associated macrophages and neutrophils in tumor progression. J Cell Physiol 228:1404-1412.
28. Lin EY, Li JF, Gnatovskiy L, Deng Y, Zhu L, et al. (2006) Macrophages regulate the angiogenic switch in a mouse model of breast cancer. Cancer Res 66:11238-11246.
29. Clear AJ, Lee AM, Calaminici M, Ramsay AG, Morris KJ, et al. (2010) Increased angiogenic sprouting in poor prognosis FL is associated with elevated numbers of CD163+ macrophages within the immediate sprouting microenvironment. Blood 115:5053-5056.
30. Sarraf KM, Belcher E, Raevsky E, Nicholson AG, Goldstraw P, et al. (2009) Neutrophil/lymphocyte ratio and its association with survival after complete resection in non-small cell lung cancer. J Thorac Cardiovasc Surg 137:425-428.
31. Dou X, Wang RB, Yan HJ, Jiang SM, Meng XJ, et al. (2013) Circulating lymphocytes as predictors of sensitivity to preoperative chemoradiotherapy in rectal cancer cases. Asian Pac J Cancer Prev 14:3881-3885.
32. Zhang J, Huang SH, Li H, Li Y, Chen XL, et al. (2013) Preoperative lymphocyte count is a favorable prognostic factor of disease-free survival in nonsmall-cell lung cancer. Med Oncol 30:352.
33. Kobayashi N, Usui S, Kikuchi S, Goto Y, Sakai M, et al. (2012) Preoperative lymphocyte count is an independent prognostic factor in node-negative nonsmall cell lung cancer. Lung Cancer 75:223-227.