Multiple fragment docking and linking in primary and secondary pockets of dopamine receptors

ACS Medicinal Chemistry Letters

Volumn 5, Issue 9, 2014, Pages 1010-1014

  Vass, Márton ^a   Ágai Csongor, Éva ^a   Horti, Ferenc ^a   Keseru, György M ^b  

^a GEDEON RICHTER LTD   (Hungary)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

dopamine receptors; Fragment docking; fragment linking; G protein coupled receptors; selective antagonists

Indexed keywords

DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE RECEPTOR; ETICLOPRIDE; N [4 [2 (6 CYANO 1,2,3,4 TETRAHYDRO 2 ISOQUINOLINYL)ETHYL]CYCLOHEXYL] 4 QUINOLINECARBOXAMIDE; RACLOPRIDE;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; COMPUTATIONAL FLUID DYNAMICS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG SYNTHESIS; IN VITRO STUDY; MOLECULAR DOCKING; PEPTIDE LIBRARY; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; STEREOCHEMISTRY;

EID: 84907510306     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml500201u     Document Type: Article

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