Molecular characterisation and control of Acinetobacter baumannii isolates resistant to multi-drugs emerging in inter-intensive care units

Annals of Clinical Microbiology and Antimicrobials

Volumn 13, Issue 1, 2014, Pages

  Ertürk, Ayşe ^a   Çiçek, Ayşegül Çopur ^a   Gümüş, Aziz ^a   Cüre, Erkan ^a   Şen, Ahmet ^a   Kurt, Aysel ^a   Karagöz, Alper ^b   Aydoğan, Nebahat ^a   Sandalli, Cemal ^a   Durmaz, Riza ^c  

^a RECEP TAYYIP ERDOGAN UNIVERSITY   (Turkey)

^b Department of Microbiology Reference Laboratories   (Turkey)

^c YILDIRIM BEYAZIT UNIVERSITY   (Turkey)

Author keywords

Acinetobacter baumannii; Clonal relation; OXA; PFGE

Indexed keywords

AMIKACIN; CEFEPIME; CEFTAZIDIME; CIPROFLOXACIN; COLISTIN; COTRIMOXAZOLE; GENTAMICIN; IMIPENEM; MEROPENEM; NETILMICIN; PIPERACILLIN PLUS TAZOBACTAM; SULTAMICILLIN; TIGECYCLINE; TOBRAMYCIN; BACTERIAL DNA; BETA LACTAMASE; RIBOSOME DNA; RNA 16S;

ACINETOBACTER BAUMANNII; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL GENETICS; BACTERIAL STRAIN; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; CONTROLLED STUDY; GENE AMPLIFICATION; HEALTH CARE PERSONNEL; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MOLECULAR CLONING; MULTIDRUG RESISTANCE; NONHUMAN; POLYMERASE CHAIN REACTION; PULSED FIELD GEL ELECTROPHORESIS; RNA SEQUENCE; TURKEY (REPUBLIC); ACINETOBACTER INFECTIONS; CHEMISTRY; CLASSIFICATION; CLUSTER ANALYSIS; CROSS INFECTION; DNA SEQUENCE; DRUG EFFECTS; EPIDEMIC; GENETICS; GENOTYPE; HETEROZYGOTE; ISOLATION AND PURIFICATION; MICROBIOLOGY; MOLECULAR EPIDEMIOLOGY; MOLECULAR TYPING; TURKEY;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTIONS; BETA-LACTAMASES; CARRIER STATE; CLUSTER ANALYSIS; CROSS INFECTION; DISEASE OUTBREAKS; DNA, BACTERIAL; DNA, RIBOSOMAL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; ENVIRONMENTAL MICROBIOLOGY; GENOTYPE; HUMANS; INTENSIVE CARE UNITS; MOLECULAR EPIDEMIOLOGY; MOLECULAR TYPING; POLYMERASE CHAIN REACTION; RNA, RIBOSOMAL, 16S; SEQUENCE ANALYSIS, DNA; TURKEY;

EID: 84907506400     PISSN: None     EISSN: 14760711     Source Type: Journal    
DOI: 10.1186/s12941-014-0036-2     Document Type: Article

References (38)

1. Garnacho-Montero J, Amaya-Villar R: Multiresis-tant Acinetobacter baumannii infections: epidemiology and management. Curr Opin Infect Dis 2010, 23:332-339.
2. Gordon NC, Wareham DW: Multidrug-resistant Acinetobacter baumannii: mechanisms of virulence and resistance. Int J Antimicrob Agents 2010, 35:219-226.
3. Garnacho-Montero J, Ortiz-Leyba C, Fernández-Hinojosa E, Aldabó-Pallás T, Cayuela A, Marquez-Vácaro JA, Garcia-Curiel A, Jiménez-Jiménez FJ: Acinetobacter baumannii ventilator-associated pneumonia: epidemical and clinical findings. Intensive Care Med 2005, 31:649-655.
4. Ayan M, Durmaz R, Aktas E, Durmaz B: Bacteriological, clinical and epidemiological characteristics of hospital-acquired Acinetobacter baumannii infection in a teaching hospital. J Hosp Infect 2003, 54:39-45.
5. Hosoglu S, Hascuhadar M, Yasar E, Uslu S, Aldudak B: Control of an Acinetobacter baumannii outbreak in a neonatal ICU without suspension of service: a devastating outbreak in Diyarbakir, Turkey. Infection 2012, 40:11-18.
6. Schreckenberger PC, Daneshvar MI, Hollis DG: Acinetobacter , Achromo-bacter , Chryseobacterium , Moraxella ve diğer nonfermentatif gram-negatif basiller. In Klinik mikrobiyoloji. 9th edition. Edited by Murray PR, Baron EJ, Jorgensen JH, Landry ML, Pfaller MA. Ankara: Atlas Kitapçilik; 2009:770-802. Edited by: A. Başustaoğlu.
7. Towner KJ: Acinetobacter: an old friend, but a new enemy. J Hosp Infect 2009, 73:355-363.
8. Poirel L, Nordmann P: Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology. Clin Microbiol Infect 2006, 12:826-836.
9. Gordon NC, Wareham DW: A review of clinical and microbiological outcomes following treatment of infections involving multidrug-resistant Acinetobacter baumannii with tigecycline. J Antimicrob Chemother 2009, 63:775-780.
10. Kalin G, Alp E, Akin A, Coskun R, Doganay M: Comparison of colistin and colistin/sulbactam for the treatment of multidrug resistant Acinetobacter baumannii ventilator-associated pneumonia. Infection 2013, doi:10.1007/s15010-013-0495-y.
11. Peleg AY, Potoski BA, Rea R, Adams J, Sethi J, Capitano B, Husain S, Kwak EJ, Bhat SV, Paterson DL: Acinetobacter baumannii bloodstream infection while receiving tigecycline: a cautionary report. J Antimicrob Chemother 2007, 59:128-131.
12. Zer Y, Özgür E, Namiduru M: Acinetobacter baumannii suşlarinda tigesiklin etkinliğinin araştirilmasi. I˙nfeksiyon Derg 2007, 21:193-196.
13. Coelho JM, Turton JF, Kaufmann ME, Glover J, Woodford N, Warner M, Palepou MF, Pike R, Pitt TL, Patel BC, Livermore DM: Occurrence of carbapenem-resistant Acinetobacter baumannii clones at multiple hospitals in London and Southeast England. J Clin Microbiol 2006, 44:3623-3627.
14. Idzenga D, Schouten MA, van Zanten AR: Outbreak of Acinetobac ter genomic species 3 in a Dutch intensive care unit. J Hosp Infect 2006, 63:485-487.
15. Nemec A, Dijkshoorn L, van der Reijden TJ: Long-term predominance of two pan-European clones among multi-resistant Acinetobacter baumannii strains in the Czech Republic. J Med Microbiol 2004, 53:147-153.
16. Turton JF, Kaufmann ME, Warner M, Coelho J, Dijkshoorn L, van der Reijden T, Pitt TL: A prevalent multiresistant clone of Acinetobacter baumannii in Southeast England. J Hosp Infect 2004, 58:170-179.
17. Van Dessel H, Dijkshoorn L, van der Reijden T, Bakker N, Paauw A, van den Broek P, Verhoef J, Brisse S: Identification of a new geographically widespread multiresistant Acinetobacter baumannii clone from European hospitals. Res Microbiol 2004, 155:105-112.
18. Clinical and Laboratory Standards Institute: Performance standards for antimicrobial susceptibility testing: twentieth informational supplement, M100-S20. Wayne, PA: CLSI; 2010.
19. Galani I, Kontopidou F, Souli M, Rekatsina PD, Koratzanis E, Deliolanis J, Giamarellou H: Colistin susceptibility testing by E test and disk diffusion methods. Int J Antimicrob Agents 2008, 31(5):434-439.
20. Jones R, Feraro M, Relle L, Schreckenbeger P, Swenson J, Sader H: Multicenter studies of tigecycline disk diffusion susceptibity results for Acinetobacter spp. J Clin Microbiol 2007, 6:227-230.
21. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ: Basic local alignment search tool. J Mol Biol 1990, 215:403-410.
22. Woodford N, Ellington MJ, Coelho JM, Turton JF, Ward ME, Brown S, Amyes SG, Livermore DM: Multiplex PCR for genes encoding prevalent OXA carbapenemases in Acinetobacter spp. Int J Antimicrob Agent 2006, 27:351-353.
23. Poirel L, Heritier C, Tol'un V, Nordmann P: Emergence of oxacillinase-mediated resistance to imipenem in Klebsiella pneumoniae. Antimicrob Agents Chemother 2004, 48:15-22.
24. Durmaz R, Otlu B, Koksal F: The optimization of a rapid pulsed-field gel electrophoresis protocol for the typing of Acinetobacter baumannii , Escherichia coli and Klebsiella spp. Jpn J Infect Dis 2009, 62:372-377.
25. Tenover FC, Arbeit RD, Goering RV, Mickelsen PA, Murray BE, Persing DH, Swaminathan B: Interpre-ting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995, 33:2233-2239.
26. Giamarellou H, Antoniadou A, Kanellakopoulou K: Acinetobacter baumannii: a universal threat to public health? Int J Antimicrob Agents 2008, 32:106-119.
27. Poirel L, Naas T, Nordmann P: Diversity, epidemiology, and genetics of class D β-lactamases. Antimicrob Agents Chemother 2010, 54:24-38.
28. Durante-Mangoni E, Zarrilli R: Global spread of drug-resistant Acinetobacter baumannii: molecular epidemiology and management of antimicrobial resistance. Future Microbiol 2011, 6:407-422.
29. Baran G, Erbay A, Bodur H, Onguru P, Akinci E, Balaban N, Cevik MA: Risk factors for nosocomial imipenem-resistant Acinetobacter baumannii infections. Int J Infect Dis 2008, 12:16-21.
30. Hande Aydemir GC, Nihal P, Nefise O, Aysegul Seremet K, Elif A, Vildan S, Deniz A: Mortality attributable to carbapenem-resistant nosocomial Acinetobacter baumannii Infections in a Turkish University Hospital. Jpn J Infect Dis 2012, 65:66-71.
31. Lee K, Yong D, Jeong SH, Chong Y: Multidrug-resistant Acinetobacter spp.: increasingly problematic nosocomial pathogens. Yonsei Med J 2011, 52:879-891.
32. Choi WS, Kim SH, Jeon EG, Son MH, Yoon YK, Kim JY, Kim MJ, Sohn JW, Kim MJ, Park DW: Nosocomial outbreak of carbapenem-resistant Acinetobacter baumannii in intensive care units and successful outbreak control program. J Korean Med Sci 2010, 25:999-1004.
33. Doidge M, Allworth AM, Woods M, Marshall P, Terry M, O'Brien K, Goh HM, George N, Nimmo GR, Schembri MA, Lipman J, Paterson DL: Control of an outbreak of carbapenem-resistant Acinetobacter baumannii in Australia after introduction of environmental cleaning with a commercial oxidizing disinfectant. Infect Control Hosp Epidemiol 2010, 31:418-420.
34. Consales G, Gramigni E, Zamidei L, Bettocchi D, De Gaudio AR: A multidrug-resistant Acinetobacter baumannii outbreak in intensive care unit: Antimicrobial and organizational strategies. J Crit Care 2011, 26:453-459.
35. Lin WR, Lu PL, Siu LK, Chen TC, Lin CY, Hung CT, Chen YH: Rapid control of a hospital-wide outbreak caused by extensively drug-resistant OXA-72-producing Acinetobacter baumannii. Kaohsiung J Med Sci 2011, 27:207-214.
36. Baang JH, Axelrod P, Decker BK, Hujer AM, Dash G, Truant AR, Bonomo RA, Fekete T: Longitudinal epidemiology of multidrug-resistant (MDR) Acinetobacter species in a tertiary care hospital. Am J Infect Control 2012, 40:134-137.
37. Herruzo R, de la Cruz J, Fernández-Aceñero MJ, Garcia-Caballero J: Two consecutive outbreaks of Acinetobacter baumannii 1-a in a burn intensive care unit for adults. Burns 2004, 30:419-423.
38. Seifert H, Dolzani L, Bressan R, van der Reijden T, van Strijen B, Stefanik D, Heersma H, Dijkshoorn L: Standardization and interlaboratory reproducibility assessment of pulsed-field gel electrophoresis-generated fingerprints of Acinetobacter baumannii. J Clin Microbiol 2005, 43:4328-4335.