Fluorodeoxyuridine enhances the heat shock response and decreases polyglutamine aggregation in an HSF-1-dependent manner in Caenorhabditis elegans

Mechanisms of Ageing and Development

Volumn 141, Issue , 2014, Pages 1-4

  Brunquell, Jessica ^a   Bowers, Philip ^a   Westerheide, Sandy D ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Caenorhabditis elegans; Fluorodeoxyuridine; Heat shock response; HSF 1; Polyglutamine model; Proteostasis

Indexed keywords

FLOXURIDINE; HEAT SHOCK TRANSCRIPTION FACTOR 1; MESSENGER RNA; POLYGLUTAMINE; ANTINEOPLASTIC ANTIMETABOLITE; CAENORHABDITIS ELEGANS PROTEIN; DNA BINDING PROTEIN; HEAT SHOCK PROTEIN; HEAT STRESS TRANSCRIPTION FACTORS; PEPTIDE; TRANSCRIPTION FACTOR; VEGETABLE PROTEIN;

ARTICLE; CAENORHABDITIS ELEGANS; CARBOXY TERMINAL SEQUENCE; GENE SILENCING; GROWTH INHIBITION; HEAT SHOCK RESPONSE; LARVAL STAGE; NONHUMAN; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN HOMEOSTASIS; RNA INTERFERENCE; ANIMAL; DISEASE MODEL; DRUG EFFECTS; HUNTINGTON DISEASE; METABOLISM;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; FLOXURIDINE; HEAT-SHOCK PROTEINS; HEAT-SHOCK RESPONSE; HUNTINGTON DISEASE; PEPTIDES; PLANT PROTEINS; TRANSCRIPTION FACTORS;

EID: 84907500678     PISSN: 00476374     EISSN: 18726216     Source Type: Journal    
DOI: 10.1016/j.mad.2014.08.002     Document Type: Article

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