Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer

Science

Volumn 346, Issue 6205, 2014, Pages 85-89

  Theurillat, Jean Philippe P ^a,b,c   Udeshi, Namrata D ^a   Errington, Wesley J ^d,e   Svinkina, Tanya ^a   Baca, Sylvan C ^b,c   Pop, Marius ^a,b,c   Wild, Peter J ^f   Blattner, Mirjam ^g   Groner, Anna C ^c   Rubin, Mark A ^g   Moch, Holger ^f   Privé, Gilbert G ^d,e   Carr, Steven A ^a   Garraway, Levi A ^a,b,c  

^a BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

^d UNIVERSITY OF TORONTO   (Canada)

^e PRINCESS MARGARET HOSPITAL   (Canada)

^f UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^g WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; DEK PROTEIN, HUMAN; NONHISTONE PROTEIN; NUCLEAR PROTEIN; ONCOPROTEIN; PROTEASOME; REPRESSOR PROTEIN; SPOP PROTEIN, HUMAN; TRIM24 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

ARTICLE; BINDING SITE; CARCINOGENESIS; GENETICS; HUMAN; MALE; METABOLISM; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; PATHOLOGY; PROSTATE TUMOR; TUMOR CELL LINE; TUMOR INVASION; UBIQUITINATION;

BASE SEQUENCE; BINDING SITES; CARCINOGENESIS; CARRIER PROTEINS; CELL LINE, TUMOR; CHROMOSOMAL PROTEINS, NON-HISTONE; HUMANS; MALE; MOLECULAR SEQUENCE DATA; MUTATION; NEOPLASM INVASIVENESS; NUCLEAR PROTEINS; ONCOGENE PROTEINS; PROSTATIC NEOPLASMS; PROTEASOME ENDOPEPTIDASE COMPLEX; REPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84907485595     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1250255     Document Type: Article

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