Metformin inhibits epithelial-mesenchymal transition in prostate cancer cells: Involvement of the tumor suppressor miR30a and its target gene SOX4

Biochemical and Biophysical Research Communications

Volumn 452, Issue 3, 2014, Pages 746-752

  Zhang, Jing ^a   Shen, Chengwu ^a   Wang, Lin ^a,b   Ma, Quanping ^c   Xia, Pingtian ^a   Qi, Mei ^a   Yang, Muyi ^a   Han, Bo ^a,d  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY   (China)

^c Fourth People's Hospital of Jinan   (China)

^d SHANDONG UNIVERSITY   (China)

Author keywords

Epithelial mesenchymal transition; Metformin; miR30a; Prostate cancer; SOX4

Indexed keywords

BETA CATENIN; DICER; METFORMIN; MICRORNA; MICRORNA 30A; NERVE CELL ADHESION MOLECULE; TRANSCRIPTION FACTOR SOX4; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; ANTIDIABETIC AGENT; CADHERIN; CDH2 PROTEIN, HUMAN; CTNNB1 PROTEIN, HUMAN; LEUKOCYTE ANTIGEN; LUCIFERASE; MESSENGER RNA; MIRN30 MICRORNA, HUMAN; SOX4 PROTEIN, HUMAN; TRANSCRIPTION FACTOR SOX;

ARTICLE; CELL CYCLE ARREST; CELL CYCLE PHASE; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; EPITHELIAL MESENCHYMAL TRANSITION; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; METASTASIS; PROSTATE CANCER CELL LINE; UPREGULATION; CELL MOTION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; PATHOLOGY; PROSTATE; PROSTATE TUMOR; PROSTATECTOMY; REPORTER GENE; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTIGENS, CD; BETA CATENIN; CADHERINS; CELL LINE, TUMOR; CELL MOVEMENT; EPITHELIAL-MESENCHYMAL TRANSITION; G1 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; HUMANS; HYPOGLYCEMIC AGENTS; LUCIFERASES; MALE; METFORMIN; MICRORNAS; PROSTATE; PROSTATECTOMY; PROSTATIC NEOPLASMS; RNA, MESSENGER; SIGNAL TRANSDUCTION; SOXC TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84907479337     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.08.154     Document Type: Article

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