Phenotypic Characterization of the KK/HlJ Inbred Mouse Strain

Veterinary Pathology

Volumn 51, Issue 4, 2014, Pages 846-857

  Berndt, A ^a   Sundberg, B A ^b   Silva, K A ^b   Kennedy, V E ^b   Richardson, M A ^a   Li, Q ^c   Bronson, R T ^b   Uitto, J ^c   Sundberg, J P ^b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b JACKSON LABORATORY   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

ectopic mineralization; KK HlJ mice; PXE model; systemic mineralization; vibrissae dermal sheath

Indexed keywords

AGE; ANIMAL; ANIMAL MODEL; CALCINOSIS; CONGENITAL MALFORMATION; INBRED MOUSE STRAIN; MOUSE; PATHOLOGY; PHENOTYPE; SEX DIFFERENCE; VIBRISSA;

AGE FACTORS; ANIMALS; CALCINOSIS; MICE; MICE, INBRED STRAINS; MODELS, ANIMAL; PHENOTYPE; SEX FACTORS; VIBRISSAE;

EID: 84907466833     PISSN: 03009858     EISSN: 15442217     Source Type: Journal    
DOI: 10.1177/0300985813501335     Document Type: Article

References (39)

1. Austin CP,Battey JF,Bradley A, et al.The knockout mouse project.Nat Genet. 2004;36:921-924
2. Bechtold LSSystematic Characterization of Mouse Mutations. Sundberg JPBoggess D, ed. Boca Raton, FL: CRC Press; 2000:121-129.
3. Begley DA,Krupke DM,Neuhauser SB, et al.The Mouse Tumor Biology Database (MTB): a central electronic resource for locating and integrating mouse tumor pathology data.Vet Pathol. 2012;49:218-223
4. Berndt A,Leme AS,Williams LK, et al.Comparison of unrestrained plethysmography and forced oscillation for identifying genetic variability of airway responsiveness in inbred mice.Physiol Genomics. 2011;43:1-11
5. Berndt A,Li Q,Potter CS, et al.A single-nucleotide polymorphism in the Abcc6 gene associates with connective tissue mineralization in mice similar to targeted models for pseudoxanthoma elasticum.J Invest Dermatol. 2013;133:833-836
6. Ewart SL,Kuperman D,Schadt E, et al.Quantitative trait loci controlling allergen-induced airway hyperresponsiveness in inbred mice.Am J Respir Cell Mol Biol. 2000;23:537-545
7. Ewart SL,Mitzner W,DiSilvestre DA, et al.Airway hyperresponsiveness to acetylcholine: segregation analysis and evidence for linkage to murine chromosome 6.Am J Respir Cell Mol Biol. 1996;14:487-495
8. Frith CH,Ward JMColor Alas of Neoplastic and Non-Neoplastic Lesions in Aging Mice. Amsterdam: Elsevier; 1988:
9. Gorgels TG,Hu X,Scheffer GL, et al.Disruption of Abcc6 in the mouse: novel insight in the pathogenesis of pseudoxanthoma elasticum.Hum Mol Genet. 2005;14:1763-1773
10. Han BG,Hao CM,Tchekneva EE, et al.Markers of glycemic control in the mouse: comparisons of 6-h- and overnight-fasted blood glucoses to Hb A1c.Am J Physiol Endocrinol Metab. 2008;295:E981-E986
11. Hayamizu TF,Mangan M,Corradi JP, et al.The Adult Mouse Anatomical Dictionary: a tool for annotating and integrating data.Genome Biol. 2005;6:R29
12. Herberg L,Coleman DL.Laboratory animals exhibiting obesity and diabetes syndromes.Metabolism. 1977;26:59-99
13. Huang LH,Sery TW.Corneal degeneration in a congenitally diabetic inbred strain of mouse.Br J Ophthalmol. 1971;55:266-271
14. Ikeda H.KK mouse.Diabetes Res Clin Pract. 1994;24 (suppl): S313-S316
15. Kavukcuoglu NB,Li Q,Pleshko N, et al.Connective tissue mineralization in Abcc6–/– mice, a model for pseudoxanthoma elasticum.Matrix Biol. 2012;31:246-252
16. Klement JF,Matsuzaki Y,Jiang QJ, et al.Targeted ablation of the Abcc6 gene results in ectopic mineralization of connective tissues.Mol Cell Biol. 2005;25:8299-8310
17. Krupke DM,Begley DA,Sundberg JP, et al.The Mouse Tumor Biology database.Nat Rev Cancer. 2008;8:459-465
18. Leiter EH.Selecting the “right” mouse model for metabolic syndrome and type 2 diabetes research.Methods Mol Biol. 2009;560:1-17
19. Leme AS,Berndt A,Williams LK, et al.A survey of airway responsiveness in 36 inbred mouse strains facilitates gene mapping studies and identification of quantitative trait loci.Mol Genet Genomics. 2010;283:317-326
20. Li Q,Berndt A,Guo H, et al.A novel animal model for pseudoxanthoma elasticum: the KK/HlJ mouse.Am J Pathol. 2012;181:1190-1196
21. Lu G,Uga S,Miyata M, et al.Histopathological study of congenitally diabetic yellow KK mouse lens.Jpn J Ophthalmol. 1993;37:369-378
22. Mecklenburg L,Paus R,Halata Z, et al.FOXN1 is critical for onycholemmal terminal differentiation in nude (Foxn1) mice.J Invest Dermatol. 2004;123:1001-1011
23. Mohr U,Dungworth DL,Capen CC, et alPathobiology of the Aging Mouse. Washington, DC: ILSI Press; 1996:
24. Mohr U,Dungworth DL,Capen CC, et alPathobiology of the Aging Mouse. Washington, DC: ILSI Press; 1996:
25. Qi Z,Fujita H,Jin J, et al.Characterization of susceptibility of inbred mouse strains to diabetic nephropathy.Diabetes. 2005;54:2628-2637
26. Reddi AS,Velasco CA,Reddy PR, et al.Diabetic microangiopathy in KK mice, VI: effect of glycemic control on renal glycoprotein metabolism and established glomerulosclerosis.Exp Mol Pathol. 1990;53:140-151
27. Sass B,Vernon ML,Peters RL, et al.Mammary tumors, hepatocellular carcinomas, and pancreatic islet changes in C3H-Avy Mice.J Natl Cancer Inst. 1978;60:611-621
28. Schofield PN,Sundberg JP,Sundberg BA, et al.The mouse pathology ontology, MPATH: structure and applications.J Biomed Semantics. In press;:
29. Shimada T.Correlation between metabolic and histopathological changes in the myocardium of the KK mouse: effect of diltiazem on the diabetic heart.Jpn Heart J. 1993;34:617-626
30. Silva KA,Sundberg JPThe Laboratory Mouse. Hedrich HJ, ed. London: Academic Press; 2012:
31. Silver LMMouse Genetics: Concepts and Applications. New York: Oxford University Press; 1995:
32. Smith RS,John SWM,Nashina PM, et alSystematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods. Boca Raton, FL: CRC Press; 2002:
33. Staats J.Standardized nomenclature for inbred strains of mice: fifth listing.Cancer Res. 1972;32:1609-1646
34. Sundberg BA,Schofield PN,Gruenberger M, et al.A data-capture tool for mouse pathology phenotyping.Vet Pathol. 2009;46:1230-1240
35. Sundberg JP,Benrdt A,Sundberg BA, et al.The mouse as a model for understanding chronic diseases of aging: the histopathologic basis of aging in inbred mice [published online June 1, 2011].Pathobiol Aging Age Relat Dis.:
36. Sundberg JP,Sundberg BA,Schofield P.Integrating mouse anatomy and pathology ontologies into a phenotyping database: tools for data capture and training.Mamm Genome. 2008;19:413-419
37. Tordoff MG,Bachmanov AA,Reed DR.Forty mouse strain survey of voluntary calcium intake, blood calcium, and bone mineral content.Physiol Behav. 2007;91:632-643
38. Wills-Karp M,Ewart SL.The genetics of allergen-induced airway hyperresponsiveness in mice.Am J Respir Crit Care Med. 1997;156:S89-S96
39. Zheng QY,Johnson KR,Erway LC.Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses.Hear Res. 1999;130:94-107