Niacin attenuates the production of pro-inflammatory cytokines in LPS-induced mouse alveolar macrophages by HCA2 dependent mechanisms

International Immunopharmacology

Volumn 23, Issue 1, 2014, Pages 121-126

  Zhou, Ershun ^a   Li, Yimeng ^a   Yao, Minjun ^a   Wei, Zhengkai ^a   Fu, Yunhe ^a   Yang, Zhengtao ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

Cytokines; HCA2; Mouse alveolar macrophages; Niacin

Indexed keywords

CYTOKINE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; G PROTEIN COUPLED RECEPTOR; HCA2 PROTEIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; NICOTINIC ACID; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ADENYLATE CYCLASE; ADENYLYL CYCLASE 2; AUTACOID; LIPOPOLYSACCHARIDE; NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATTENUATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; GENE SILENCING; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS MACROPHAGE; MALE; MEDIATOR; MOUSE; NONHUMAN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; ANIMAL; C57BL MOUSE; DRUG EFFECTS; GENETICS; IMMUNOLOGY; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; TRANSCRIPTION INITIATION;

ADENYLATE CYCLASE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CYTOKINES; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MACROPHAGES, ALVEOLAR; MALE; MICE; MICE, INBRED C57BL; NF-KAPPA B; NIACIN; PHOSPHORYLATION; RNA, SMALL INTERFERING; TRANSCRIPTIONAL ACTIVATION;

EID: 84907434361     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.07.006     Document Type: Article

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