메뉴 건너뛰기




Volumn 30, Issue 8, 2014, Pages 742-748

Lixisenatide as add-on to oral anti-diabetic therapy: An effective treatment for glycaemic control with body weight benefits in type 2 diabetes

Author keywords

Glycaemic control; Lixisenatide; Oral anti diabetics; Prandial; Type 2 diabetes mellitus

Indexed keywords

GLUCOSE; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C; LIXISENATIDE; ORAL ANTIDIABETIC AGENT; PLACEBO; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIDIABETIC AGENT; GLUCAGON RECEPTOR; GLUCAGON-LIKE PEPTIDE-1 RECEPTOR; HEMOGLOBIN A1C PROTEIN, HUMAN; METFORMIN; PEPTIDE; PIOGLITAZONE; SULFONYLUREA DERIVATIVE; ZP10A PEPTIDE;

EID: 84907429773     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.2548     Document Type: Article
Times cited : (13)

References (32)
  • 1
    • 84890566037 scopus 로고    scopus 로고
    • American Association of Clinical Endocrinologists' comprehensive diabetes management algorithm 2013 consensus statement - executive summary
    • Garber AJ, Abrahamson MJ, Barzilay JI, et al. American Association of Clinical Endocrinologists' comprehensive diabetes management algorithm 2013 consensus statement - executive summary. Endocr Pract 2013; 19: 536-557.
    • (2013) Endocr Pract , vol.19 , pp. 536-557
    • Garber, A.J.1    Abrahamson, M.J.2    Barzilay, J.I.3
  • 2
    • 33846414720 scopus 로고    scopus 로고
    • Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary. The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD)
    • Ryden L, Standl E, Bartnik M, et al. Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary. The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD). Eur Heart J 2007; 28: 88-136.
    • (2007) Eur Heart J , vol.28 , pp. 88-136
    • Ryden, L.1    Standl, E.2    Bartnik, M.3
  • 3
    • 84878358313 scopus 로고    scopus 로고
    • Efficacy and safety of lixisenatide once-daily morning or evening injections in type 2 diabetes inadequately controlled on metformin (GetGoal-M)
    • Ahren B, Leguizamo DA, Miossec P, Saubadu S, Aronson R. Efficacy and safety of lixisenatide once-daily morning or evening injections in type 2 diabetes inadequately controlled on metformin (GetGoal-M). Diabetes Care 2013; 36: 2543-2550.
    • (2013) Diabetes Care , vol.36 , pp. 2543-2550
    • Ahren, B.1    Leguizamo, D.A.2    Miossec, P.3    Saubadu, S.4    Aronson, R.5
  • 4
    • 84861765116 scopus 로고    scopus 로고
    • Efficacy and safety of the once-daily GLP-1 receptor agonist lixisenatide in monotherapy: a randomized, double-blind, placebo-controlled trial in patients with type 2 diabetes (GetGoal-Mono)
    • Fonseca VA, Alvarado-Ruiz R, Raccah D, Boka G, Miossec P, Gerich JE. Efficacy and safety of the once-daily GLP-1 receptor agonist lixisenatide in monotherapy: a randomized, double-blind, placebo-controlled trial in patients with type 2 diabetes (GetGoal-Mono). Diabetes Care 2012; 35: 1225-1231.
    • (2012) Diabetes Care , vol.35 , pp. 1225-1231
    • Fonseca, V.A.1    Alvarado-Ruiz, R.2    Raccah, D.3    Boka, G.4    Miossec, P.5    Gerich, J.E.6
  • 5
    • 84878592117 scopus 로고    scopus 로고
    • Adding once-daily lixisenatide for type 2 diabetes inadequately controlled by established basal insulin: a 24-week, randomized, placebo-controlled comparison (GetGoal-L)
    • Riddle MC, Aronson R, Home P, et al. Adding once-daily lixisenatide for type 2 diabetes inadequately controlled by established basal insulin: a 24-week, randomized, placebo-controlled comparison (GetGoal-L). Diabetes Care 2013; 36: 2489-2496.
    • (2013) Diabetes Care , vol.36 , pp. 2489-2496
    • Riddle, M.C.1    Aronson, R.2    Home, P.3
  • 6
    • 84878603672 scopus 로고    scopus 로고
    • Adding once-daily lixisenatide for type 2 diabetes inadequately controlled with newly initiated and continuously titrated basal insulin glargine: a 24-week, randomized, placebo-controlled study (GetGoal-Duo 1)
    • Riddle MC, Forst T, Aronson R, et al. Adding once-daily lixisenatide for type 2 diabetes inadequately controlled with newly initiated and continuously titrated basal insulin glargine: a 24-week, randomized, placebo-controlled study (GetGoal-Duo 1). Diabetes Care 2013; 36: 2497-2503.
    • (2013) Diabetes Care , vol.36 , pp. 2497-2503
    • Riddle, M.C.1    Forst, T.2    Aronson, R.3
  • 7
    • 84865979163 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled trial of the once-daily GLP-1 receptor agonist lixisenatide in Asian patients with type 2 diabetes insufficiently controlled on basal insulin with or without a sulfonylurea (GetGoal-L-Asia)
    • Seino Y, Min KW, Niemoeller E, Takami A. Randomized, double-blind, placebo-controlled trial of the once-daily GLP-1 receptor agonist lixisenatide in Asian patients with type 2 diabetes insufficiently controlled on basal insulin with or without a sulfonylurea (GetGoal-L-Asia). Diabetes Obes Metab 2012; 14: 910-917.
    • (2012) Diabetes Obes Metab , vol.14 , pp. 910-917
    • Seino, Y.1    Min, K.W.2    Niemoeller, E.3    Takami, A.4
  • 8
    • 84892556531 scopus 로고    scopus 로고
    • Efficacy and safety of lixisenatide once daily versus placebo in patients with type 2 diabetes insufficiently controlled on metformin (GetGoal-F1)
    • Bolli GB, Munteanu M, Dotsenko S, et al. Efficacy and safety of lixisenatide once daily versus placebo in patients with type 2 diabetes insufficiently controlled on metformin (GetGoal-F1). Diabet Med 2014; 31: 176-184.
    • (2014) Diabet Med , vol.31 , pp. 176-184
    • Bolli, G.B.1    Munteanu, M.2    Dotsenko, S.3
  • 9
    • 84910615132 scopus 로고    scopus 로고
    • on behalf of the GetGoal-M-Asia Study Investigators
    • Lixisenatide in Asian patients with type 2 diabetes (T2DM) uncontrolled on metformin +/- sulfonylurea (SU): GetGoal-M-Asia. 9th International Diabetes Federation Western Pacific Region Congress and the 4th Scientific Meeting of the Asian Association for the Study of Diabetes, 24-27 November, Kyoto, Japan.
    • Pan CY, Shang S, Niemoeller E, on behalf of the GetGoal-M-Asia Study Investigators. Lixisenatide in Asian patients with type 2 diabetes (T2DM) uncontrolled on metformin +/- sulfonylurea (SU): GetGoal-M-Asia. 9th International Diabetes Federation Western Pacific Region Congress and the 4th Scientific Meeting of the Asian Association for the Study of Diabetes, 24-27 November 2012, Kyoto, Japan.
    • (2012)
    • Pan, C.Y.1    Shang, S.2    Niemoeller, E.3
  • 10
    • 84885331631 scopus 로고    scopus 로고
    • Efficacy and safety of lixisenatide once daily versus placebo in type 2 diabetes insufficiently controlled on pioglitazone (GetGoal-P)
    • Pinget M, Goldenberg R, Niemoeller E, Muehlen-Bartmer I, Guo H, Aronson R. Efficacy and safety of lixisenatide once daily versus placebo in type 2 diabetes insufficiently controlled on pioglitazone (GetGoal-P). Diabetes Obes Metab 2013; 15: 1000-1007. doi:10.1111/dom.12121.
    • (2013) Diabetes Obes Metab , vol.15 , pp. 1000-1007
    • Pinget, M.1    Goldenberg, R.2    Niemoeller, E.3    Muehlen-Bartmer, I.4    Guo, H.5    Aronson, R.6
  • 11
    • 84871941957 scopus 로고    scopus 로고
    • Diagnosis and classification of diabetes mellitus
    • American Diabetes Association.
    • American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 2013; 36(Suppl 1): S67-S74.
    • (2013) Diabetes Care , vol.36 , pp. S67-S74
  • 12
    • 84866268783 scopus 로고    scopus 로고
    • Management of hyperglycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
    • Inzucchi SE, Bergenstal RM, Buse JB, et al. Management of hyperglycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 2012; 35: 1364-1379.
    • (2012) Diabetes Care , vol.35 , pp. 1364-1379
    • Inzucchi, S.E.1    Bergenstal, R.M.2    Buse, J.B.3
  • 13
    • 78650720971 scopus 로고    scopus 로고
    • Initial combination therapy for type 2 diabetes mellitus: is it ready for prime time?
    • Zinman B. Initial combination therapy for type 2 diabetes mellitus: is it ready for prime time? Am J Med 2011; 124: S19-S34.
    • (2011) Am J Med , vol.124 , pp. S19-S34
    • Zinman, B.1
  • 14
    • 84883324640 scopus 로고    scopus 로고
    • Efficacy and safety of lixisenatide once daily versus exenatide twice daily in type 2 diabetes inadequately controlled on metformin: a 24-week, randomized, open-label, active-controlled study (GetGoal-X)
    • Rosenstock J, Raccah D, Koranyi L, et al. Efficacy and safety of lixisenatide once daily versus exenatide twice daily in type 2 diabetes inadequately controlled on metformin: a 24-week, randomized, open-label, active-controlled study (GetGoal-X). Diabetes Care 2013; 36: 2945-2951.
    • (2013) Diabetes Care , vol.36 , pp. 2945-2951
    • Rosenstock, J.1    Raccah, D.2    Koranyi, L.3
  • 15
    • 84863309250 scopus 로고    scopus 로고
    • Glycaemic efficacy of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors as add-on therapy to metformin in subjects with type 2 diabetes - a review and meta analysis
    • Deacon CF, Mannucci E, Ahren B. Glycaemic efficacy of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors as add-on therapy to metformin in subjects with type 2 diabetes - a review and meta analysis. Diabetes Obes Metab 2012; 14: 762-767.
    • (2012) Diabetes Obes Metab , vol.14 , pp. 762-767
    • Deacon, C.F.1    Mannucci, E.2    Ahren, B.3
  • 16
    • 79960435775 scopus 로고    scopus 로고
    • GLP-1 receptor agonists and HBA1c target of <7% in type 2 diabetes: meta-analysis of randomized controlled trials
    • Esposito K, Mosca C, Brancario C, Chiodini P, Ceriello A, Giugliano D. GLP-1 receptor agonists and HBA1c target of <7% in type 2 diabetes: meta-analysis of randomized controlled trials. Curr Med Res Opin 2011; 27: 1519-1528.
    • (2011) Curr Med Res Opin , vol.27 , pp. 1519-1528
    • Esposito, K.1    Mosca, C.2    Brancario, C.3    Chiodini, P.4    Ceriello, A.5    Giugliano, D.6
  • 17
    • 80053401330 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor agonists versus insulin in inadequately controlled patients with type 2 diabetes mellitus: a meta-analysis of clinical trials
    • Wang Y, Li L, Yang M, Liu H, Boden G, Yang G. Glucagon-like peptide-1 receptor agonists versus insulin in inadequately controlled patients with type 2 diabetes mellitus: a meta-analysis of clinical trials. Diabetes Obes Metab 2011; 13: 972-981.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 972-981
    • Wang, Y.1    Li, L.2    Yang, M.3    Liu, H.4    Boden, G.5    Yang, G.6
  • 18
    • 84884281474 scopus 로고    scopus 로고
    • Efficacy of various antidiabetic agents as add-on treatments to metformin in type 2 diabetes mellitus: systematic review and meta-analysis
    • Poolsup N, Suksomboon N, Setwiwattanakul W. Efficacy of various antidiabetic agents as add-on treatments to metformin in type 2 diabetes mellitus: systematic review and meta-analysis. ISRN Endocrinol 2012; 2012: 798146.
    • (2012) ISRN Endocrinol , vol.2012 , pp. 798146
    • Poolsup, N.1    Suksomboon, N.2    Setwiwattanakul, W.3
  • 19
    • 84890568491 scopus 로고    scopus 로고
    • Efficacy and safety of dipeptidyl peptidase-4 inhibitors and metformin as initial combination therapy and as monotherapy in patients with type 2 diabetes mellitus: a meta-analysis
    • Wu D, Li L, Liu C. Efficacy and safety of dipeptidyl peptidase-4 inhibitors and metformin as initial combination therapy and as monotherapy in patients with type 2 diabetes mellitus: a meta-analysis. Diabetes Obes Metab 2014; 16: 30-37.
    • (2014) Diabetes Obes Metab , vol.16 , pp. 30-37
    • Wu, D.1    Li, L.2    Liu, C.3
  • 20
    • 77950891085 scopus 로고    scopus 로고
    • Effect of noninsulin antidiabetic drugs added to metformin therapy on glycemic control, weight gain, and hypoglycemia in type 2 diabetes
    • Phung OJ, Scholle JM, Talwar M, Coleman CI. Effect of noninsulin antidiabetic drugs added to metformin therapy on glycemic control, weight gain, and hypoglycemia in type 2 diabetes. JAMA 2010; 303: 1410-1418.
    • (2010) JAMA , vol.303 , pp. 1410-1418
    • Phung, O.J.1    Scholle, J.M.2    Talwar, M.3    Coleman, C.I.4
  • 21
    • 79956351014 scopus 로고    scopus 로고
    • Effect of antihyperglycemic agents added to metformin and a sulfonylurea on glycemic control and weight gain in type 2 diabetes: a network meta-analysis
    • Gross JL, Kramer CK, Leitao CB, et al. Effect of antihyperglycemic agents added to metformin and a sulfonylurea on glycemic control and weight gain in type 2 diabetes: a network meta-analysis. Ann Intern Med 2011; 154: 672-679.
    • (2011) Ann Intern Med , vol.154 , pp. 672-679
    • Gross, J.L.1    Kramer, C.K.2    Leitao, C.B.3
  • 22
    • 84864373256 scopus 로고    scopus 로고
    • Effect of antidiabetic agents added to metformin on glycaemic control, hypoglycaemia and weight change in patients with type 2 diabetes: a network meta-analysis
    • Liu SC, Tu YK, Chien MN, Chien KL. Effect of antidiabetic agents added to metformin on glycaemic control, hypoglycaemia and weight change in patients with type 2 diabetes: a network meta-analysis. Diabetes Obes Metab 2012; 14: 810-820.
    • (2012) Diabetes Obes Metab , vol.14 , pp. 810-820
    • Liu, S.C.1    Tu, Y.K.2    Chien, M.N.3    Chien, K.L.4
  • 23
    • 84904388473 scopus 로고    scopus 로고
    • The extra-pancreatic effects of GLP-1 receptor agonists: a focus on the cardiovascular, gastrointestinal and central nervous systems
    • Seufert J, Gallwitz B. The extra-pancreatic effects of GLP-1 receptor agonists: a focus on the cardiovascular, gastrointestinal and central nervous systems. Diabetes Obes Metab 2013. doi:10.1111/dom.12251.
    • (2013) Diabetes Obes Metab
    • Seufert, J.1    Gallwitz, B.2
  • 24
    • 82655178563 scopus 로고    scopus 로고
    • Beyond metformin: initiating combination therapy in patients with type 2 diabetes mellitus
    • Goldman-Levine JD. Beyond metformin: initiating combination therapy in patients with type 2 diabetes mellitus. Pharmacotherapy 2011; 31: 44S-53S.
    • (2011) Pharmacotherapy , vol.31 , pp. 44S-53S
    • Goldman-Levine, J.D.1
  • 25
    • 0042166232 scopus 로고    scopus 로고
    • Contributions of fasting and postprandial plasma glucose increments to the overall diurnal hyperglycemia of type 2 diabetic patients: variations with increasing levels of HbA(1c)
    • Monnier L, Lapinski H, Colette C. Contributions of fasting and postprandial plasma glucose increments to the overall diurnal hyperglycemia of type 2 diabetic patients: variations with increasing levels of HbA(1c). Diabetes Care 2003; 26: 881-885.
    • (2003) Diabetes Care , vol.26 , pp. 881-885
    • Monnier, L.1    Lapinski, H.2    Colette, C.3
  • 26
    • 84859033619 scopus 로고    scopus 로고
    • Contributions of basal and postprandial hyperglycemia over a wide range of A1C levels before and after treatment intensification in type 2 diabetes
    • Riddle M, Umpierrez G, DiGenio A, Zhou R, Rosenstock J. Contributions of basal and postprandial hyperglycemia over a wide range of A1C levels before and after treatment intensification in type 2 diabetes. Diabetes Care 2011; 34: 2508-2514.
    • (2011) Diabetes Care , vol.34 , pp. 2508-2514
    • Riddle, M.1    Umpierrez, G.2    DiGenio, A.3    Zhou, R.4    Rosenstock, J.5
  • 27
    • 0030831056 scopus 로고    scopus 로고
    • Nonfasting plasma glucose is a better marker of diabetic control than fasting plasma glucose in type 2 diabetes
    • Avignon A, Radauceanu A, Monnier L. Nonfasting plasma glucose is a better marker of diabetic control than fasting plasma glucose in type 2 diabetes. Diabetes Care 1997; 20: 1822-1826.
    • (1997) Diabetes Care , vol.20 , pp. 1822-1826
    • Avignon, A.1    Radauceanu, A.2    Monnier, L.3
  • 28
    • 0032970013 scopus 로고    scopus 로고
    • How valid is fasting plasma glucose as a parameter of glycemic control in non-insulin-using patients with type 2 diabetes?
    • Bouma M, Dekker JH, de Sonnaville JJ, et al. How valid is fasting plasma glucose as a parameter of glycemic control in non-insulin-using patients with type 2 diabetes? Diabetes Care 1999; 22: 904-907.
    • (1999) Diabetes Care , vol.22 , pp. 904-907
    • Bouma, M.1    Dekker, J.H.2    de Sonnaville, J.J.3
  • 29
    • 0032829389 scopus 로고    scopus 로고
    • Postprandial plasma glucose: a good index of glycemic control in type 2 diabetic patients having near-normal fasting glucose levels
    • Soonthornpun S, Rattarasarn C, Leelawattana R, Setasuban W. Postprandial plasma glucose: a good index of glycemic control in type 2 diabetic patients having near-normal fasting glucose levels. Diabetes Res Clin Pract 1999; 46: 23-27.
    • (1999) Diabetes Res Clin Pract , vol.46 , pp. 23-27
    • Soonthornpun, S.1    Rattarasarn, C.2    Leelawattana, R.3    Setasuban, W.4
  • 30
    • 0141783961 scopus 로고    scopus 로고
    • The impact of prandial glucose regulation in practice
    • Verges B. The impact of prandial glucose regulation in practice. Diabetes Nutr Metab 2002; 15: 28-32.
    • (2002) Diabetes Nutr Metab , vol.15 , pp. 28-32
    • Verges, B.1
  • 31
    • 84878549237 scopus 로고    scopus 로고
    • Effects of lixisenatide once daily on gastric emptying in type 2 diabetes - relationship to postprandial glycemia
    • 185C
    • Lorenz M, Pfeiffer C, Steinstrasser A, et al. Effects of lixisenatide once daily on gastric emptying in type 2 diabetes - relationship to postprandial glycemia. Regul Pept 2013; 185C: 1-8.
    • (2013) Regul Pept , pp. 1-8
    • Lorenz, M.1    Pfeiffer, C.2    Steinstrasser, A.3
  • 32
    • 84878863716 scopus 로고    scopus 로고
    • Pharmacodynamic characteristics of lixisenatide once daily versus liraglutide once daily in patients with type 2 diabetes insufficiently controlled on metformin
    • Kapitza C, Forst T, Coester HV, Poitiers F, Ruus P, Hincelin-Mery A. Pharmacodynamic characteristics of lixisenatide once daily versus liraglutide once daily in patients with type 2 diabetes insufficiently controlled on metformin. Diabetes Obes Metab 2013; 15: 642-649.
    • (2013) Diabetes Obes Metab , vol.15 , pp. 642-649
    • Kapitza, C.1    Forst, T.2    Coester, H.V.3    Poitiers, F.4    Ruus, P.5    Hincelin-Mery, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.