Effect of oral magnesium supplementation on physical performance in healthy elderly women involved in a weekly exercise program: A randomized controlled trial

American Journal of Clinical Nutrition

Volumn 100, Issue 3, 2014, Pages 974-981

  Veronese, Nicola ^a   Berton, Linda ^a   Carraro, Sara ^a   Bolzetta, Francesco ^a   De Rui, Marina ^a   Perissinotto, Egle ^a   Toffanello, Elena Debora ^a   Bano, Giulia ^a   Pizzato, Simona ^a   Miotto, Fabrizia ^a   Coin, Alessandra ^a   Manzato, Enzo ^a   Sergi, Giuseppe ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

MAGNESIUM OXIDE; MAGNESIUM; PERFORMANCE ENHANCING SUBSTANCE;

AGED; ARTICLE; BODY COMPOSITION; CONTROLLED STUDY; DIARRHEA; DIETARY INTAKE; EXERCISE; FEMALE; GERIATRIC PATIENT; GRIP STRENGTH; HUMAN; HYPERMAGNESEMIA; LABORATORY TEST; MAGNESIUM DEFICIENCY; MUSCLE STRENGTH; NORMAL HUMAN; NUTRITIONAL ASSESSMENT; OUTCOME ASSESSMENT; PHYSICAL PERFORMANCE; PRURITUS; RANDOMIZED CONTROLLED TRIAL; TREATMENT DURATION; VITAMIN SUPPLEMENTATION; WALKING SPEED; AGING; BLOOD; DIET SUPPLEMENTATION; DIET THERAPY; DOUBLE BLIND PROCEDURE; FOLLOW UP; GAIT; GERIATRIC ASSESSMENT; HAND STRENGTH; ITALY; LEG; PATHOPHYSIOLOGY; PSYCHOMOTOR PERFORMANCE; SEVERITY OF ILLNESS INDEX;

AGED; AGING; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; EXERCISE; FEMALE; FOLLOW-UP STUDIES; GAIT; GERIATRIC ASSESSMENT; HAND STRENGTH; HUMANS; ITALY; LOWER EXTREMITY; MAGNESIUM; MAGNESIUM DEFICIENCY; MAGNESIUM OXIDE; MUSCLE STRENGTH; PERFORMANCE-ENHANCING SUBSTANCES; PSYCHOMOTOR PERFORMANCE; SEVERITY OF ILLNESS INDEX;

EID: 84907379689     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.113.080168     Document Type: Article

References (39)

1. Newhouse IJ, Finstad EW. The effects of magnesium supplementation on exercise performance. Clin J Sport Med 2000;10:195-200.
2. Barbagallo M, Belvedere M, Dominguez LJ. Magnesium homeostasis and aging. Magnes Res 2009;22:235-46.
3. Wolf FI, Cittadini A. Chemistry and biochemistry of magnesium. Mol Aspects Med 2003;24:3-9. (Pubitemid 36092140)
4. Bohl CH, Volpe SL. Magnesium and exercise. Crit Rev Food Sci Nutr 2002;42:533-637.
5. Lukaski HC. Magnesium, zinc, and chromium nutriture and physical activity. Am J Clin Nutr 2000;72(suppl):585S-93S. (Pubitemid 30654796)
6. Dominguez LJ, Barbagallo M, Lauretani F, Bandinelli S, Bos A, Corsi AM, Simonsick EM, Ferrucci L. Magnesium and muscle performance in older persons: the InCHIANTI study. Am J Clin Nutr 2006;84:419-26. (Pubitemid 44699155)
7. Rock E, Astier C, Lab C, Vignon X, Gueux E, Motta C, Rayssiguier Y. Dietary magnesium deficiency in rats enhances free radical production in skeletal muscle. J Nutr 1995;125:1205-10.
8. Rude RK, Singer FR, Gruber HE. Skeletal and hormonal effects of magnesium deficiency. J Am Coll Nutr 2009;28:131-41.
9. Galan P, Preziosi P, Durlach V, Valeix P, Ribas L, Bouzid D, Favier A, Hercberg S. Dietary magnesium intake in a French adult population. Magnes Res 1997;10:321-8. (Pubitemid 127525893)
10. Ahlborg B, Ekelund LG, Nilsson CG. Effect of potassium-magnesium- aspartate on the capacity for prolonged exercise in man. Acta Physiol Scand 1968;74:238-45.
11. Ripari P, Pieralisi G, Giamberardino M, Vecchiet L. Effects of magnesium picolinate on some cardiorespiratory submaximal effort parameters. Magnes Res 1989;2:4.
12. Brilla LR, Haley TF. Effect of magnesium supplementation on strength training in humans. J Am Coll Nutr 1992;11:326-9.
13. Weller E, Bachert P, Meinck HM, Friedmann B, Bartsch P, Mairbaurl H. Lack of effect of oral Mg-supplementation on Mg in serum, blood cells, and calf muscle. Med Sci Sports Exerc 1998;30:1584-91. (Pubitemid 28520522)
14. Terblanche S, Noakes TD, Dennis SC, Marais D, Eckert M. Failure of magnesium supplementation to influence marathon running performance or recovery in magnesium-replete subjects. Int J Sport Nutr 1992;2:154-64.
15. Finstad EW, Newhouse IJ, Lukaski HC, McAuliffe JE, Stewart CR. The effects of magnesium supplementation on exercise performance. Med Sci Sports Exerc 2001;33:493-8. (Pubitemid 32209672)
16. Nielsen FH, Lukaski HC. Update on the relationship between magnesium and exercise. Magnes Res 2006;19:180-9. (Pubitemid 44788513)
17. Tieland M, Brouwer-Brolsma EM, Nienaber-Rousseau C, van Loon LJ, De Groot LC. Low vitamin D status is associated with reduced muscle mass and impaired physical performance in frail elderly people. Eur J Clin Nutr 2013;67:1050-5.
18. Schulz KF, Altman DG, Moher D. CONSORT 2010 statement: Updated guidelines for reporting parallel group randomised trials. J Pharmacol Pharmacother 2010;1:100-7.
19. Institute of Medicine, Food and Nutrition Board. Dietary Reference Intakes: calcium, phosphorus, magnesium, vitamin D and fluoride. Washington, DC: National Academy Press, 1997.
20. Guralnik JM, Simonsick EM, Ferrucci L, Glynn RJ, Berkman LF, Blazer DG, Scherr PA, Wallace RB. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol 1994;49:M85-94. (Pubitemid 24100267)
21. Shepherd JA, Fan B, Lu Y, Wu XP, Wacker WK, Ergun DL, Levine MA. A multinational study to develop universal standardization of whole-body bone density and composition using GE Healthcare Lunar and Hologic DXA systems. J Bone Miner Res 2012;27:2208-16.
22. Heymsfield SB, Smith R, Aulet M, Bensen B, Lichtman S, Wang J, Pierson RN Jr. Appendicular skeletal muscle mass: measurement by dual-photon absorptiometry. Am J Clin Nutr 1990;52:214-8.
23. Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, Martin FC, Michel JP, Rolland Y, Schneider SM, et al. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing 2010;39:412-23.
24. Washburn RA, McAuley E, Katula J, Mihalko SL, Boileau RA. The physical activity scale for the elderly (PASE): evidence for validity. J Clin Epidemiol 1999;52:643-51. (Pubitemid 29281660)
25. Washburn RA, Smith KW, Jette AM, Janney CA. The Physical Activity Scale for the Elderly (PASE): development and evaluation. J Clin Epidemiol 1993;46:153-62. (Pubitemid 23092124)
26. Cameron ME, van Staveren WA. Manual of methodology for food consumption studies. Oxford, United Kingdom: Oxford University Press, 1988.
27. Nes M, van Staveren WA, Zajkas G, Inelmen EM, Moreiras O, Euronut SENECA Investigators. Validity of the dietary history method in elderly subjects. Eur J Clin Nutr 1991;45:S97-104.
28. Carnovale E, Miuccio FC. Tabelle di composizione degli alimenti. [Tables of food composition.] Rome, Italy: Ministry of Agriculture and National Institute of Nutrition, 1989 (in Italian).
29. Kwon S, Perera S, Pahor M, Katula JA, King AC, Groessl EJ, Studenski SA. What is a meaningful change in physical performance? Findings from a clinical trial in older adults (the LIFE-P study). J Nutr Health Aging 2009;13:538-44.
30. Moslehi N, Vafa M, Sarrafzadeh J, Rahimi-Foroushani A. Does magnesium supplementation improve body composition and muscle strength in middle-aged overweight women? A double-blind, placebocontrolled, randomized clinical trial. Biol Trace Elem Res 2013;153:111-8.
31. Perera S, Mody SH, Woodman RC, Studenski SA. Meaningful change and responsiveness in common physical performance measures in older adults. J Am Geriatr Soc 2006;54:743-9. (Pubitemid 44030194)
32. McCarthy EK, Horvat MA, Holtsberg PA, Wisenbaker JM. Repeated chair stands as a measure of lower limb strength in sexagenarian women. J Gerontol A Biol Sci Med Sci 2004;59:1207-12. (Pubitemid 40024281)
33. Hatzistavri LS, Sarafidis PA, Georgianos PI, Tziolas IM, Aroditis CP, Zebekakis PE, Pikilidou MI, Lasaridis AN. Oral magnesium supplementation reduces ambulatory blood pressure in patients with mild hypertension. Am J Hypertens 2009;22:1070-5.
34. Gontijo-Amaral C, Guimaraes EV, Camargos P. Oral magnesium supplementation in children with cystic fibrosis improves clinical and functional variables: a double-blind, randomized, placebo-controlled crossover trial. Am J Clin Nutr 2012;96:50-6.
35. Lukaski HC, Nielsen FH. Dietary magnesium depletion affects metabolic responses during submaximal exercise in postmenopausal women. J Nutr 2002;132:930-5. (Pubitemid 34493555)
36. Dimai HP, Porta S, Wirnsberger G, Lindschinger M, Pamperl I, Dobnig H, Wilders-Truschnig M, Lau KH. Daily oral magnesium supplementation suppresses bone turnover in young adult males. J Clin Endocrinol Metab 1998;83:2742-8. (Pubitemid 28493770)
37. Rodríguez-Moran M, Guerrero-Romero F. Oral magnesium supplementation improves insulin sensitivity and metabolic control in type 2 diabetic subjects: a randomized double-blind controlled trial. Diabetes Care 2003;26:1147-52. (Pubitemid 36929263)
38. Song Y, He K, Levitan EB, Manson JE, Liu S. Effects of oral magnesium supplementation on glycaemic control in Type 2 diabetes: a meta-analysis of randomized double-blind controlled trials. Diabet Med 2006;23:1050-6. (Pubitemid 44401132)
39. Elin RJ. Assessment of magnesium status for diagnosis and therapy. Magnes Res 2010;23:S194-8.