Organophosphate pesticide exposure, PON1, and neurodevelopment in school-age children from the CHAMACOS study

Environmental Research

Volumn 134, Issue , 2014, Pages 149-157

  Eskenazi, Brenda ^a   Kogut, Katherine ^a   Huen, Karen ^a   Harley, Kim G ^a   Bouchard, Maryse ^a,b   Bradman, Asa ^a   Boyd Barr, Dana ^c   Johnson, Caroline ^a   Holland, Nina ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c EMORY UNIVERSITY   (United States)

Author keywords

Attention; Conners' Continuous Performance Test (CPT, KCPT, K CPT); Neurodevelopment; Organophosphates; Paraoxonase; Pesticides; PON1; Wechsler Intelligence Scale for Children (WISC)

Indexed keywords

ALKANEDIOL DERIVATIVE; ARYLDIALKYLPHOSPHATASE; ARYLESTERASE; ORGANOPHOSPHATE PESTICIDE; ORGANOPHOSPHORUS COMPOUND; PESTICIDE; PON1 PROTEIN, HUMAN;

AGRICULTURAL LAND; ENZYME ACTIVITY; GENOTYPE; NEUROLOGY; ORGANOPHOSPHATE; PESTICIDE; POLLUTION EXPOSURE; PREGNANCY; TOXICITY;

ADULT; ARTICLE; COGNITION; CONNERS KIDDIE CONTINUOUS PERFORMANCE TEST; CONTINUOUS PERFORMANCE TEST; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; FEMALE; FOLLOW UP; GENE; GENETIC PREDISPOSITION; GENETIC SUSCEPTIBILITY; HUMAN; INTELLIGENCE QUOTIENT; MAJOR CLINICAL STUDY; MALE; MATERNAL BLOOD; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; NERVE CELL DIFFERENTIATION; PON1 GENE; PRENATAL EXPOSURE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; UMBILICAL CORD BLOOD; URINALYSIS; WECHSLER INTELLIGENCE SCALE; CHILD; CHILD DEVELOPMENT; DRUG EFFECTS; GENETICS; METABOLISM; NEUROPSYCHOLOGICAL TEST; PREGNANCY;

CALIFORNIA; UNITED STATES;

ADULT; ARYLDIALKYLPHOSPHATASE; CHILD; CHILD DEVELOPMENT; ENVIRONMENTAL EXPOSURE; FEMALE; HUMANS; MALE; MATERNAL EXPOSURE; NEUROPSYCHOLOGICAL TESTS; ORGANOPHOSPHORUS COMPOUNDS; PESTICIDES; PREGNANCY;

EID: 84907375523     PISSN: 00139351     EISSN: 10960953     Source Type: Journal    
DOI: 10.1016/j.envres.2014.07.001     Document Type: Article

References (47)

1. Barr D., Bravo R., Weerasekera G., Caltabiano L., Whitehead R. Concentrations of dialkyl phosphate metabolites of organophosphorus pesticides in the U.S. population. Environ. Health Perspect. 2004, 112(2):186-200.
2. Bornstein M.H., Colombo J. Infant cognitive functioning and child mental development. Early Childhood Development and Later Achievement 2012, 118-147. Cambridge University Press, New York. S. Pauen, M. Bornstein (Eds.).
3. Bouchard M.F., Chevrier J., Harley K.G., Kogut K., Vedar M., Calderon N., et al. Prenatal exposure to organophosphate pesticides and iq in 7-year-old children. Environ. Health Perspect. 2011, 119(8):1189-1195.
4. Bradman A., Barr D.B., Claus Henn B.G., Drumheller T., Curry C., Eskenazi B. Measurement of pesticides and other toxicants in amniotic fluid as a potential biomarker of prenatal exposure: a validation study. Environ. Health Perspect. 2003, 111(14):1779-1782.
5. Bradman A., Eskenazi B., Barr D., Bravo R., Castorina R., Chevrier J., et al. Organophosphate urinary metabolite levels during pregnancy and after delivery in women living in an agricultural community. Environ. Health Perspect. 2005, 113(12):1802-1807.
6. Bravo R., Driskell W.J., Whitehead R.D., Needham L.L., Barr D.B. Quantitation of dialkyl phosphate metabolites of organophosphate pesticides in human urine using GC-MS-MS with isotopic internal standards. J. Anal. Toxicol. 2002, 26(5):245-252.
7. Caldwell B., Bradley R. Home Observation For Measurement Of The Environment 1984, University of Arkansas, Little Rock, AR.
8. Chen J., Kumar M., Chan W., Berkowitz G., Wetmur J.G. Increased influence of genetic variation on PON1 activity in neonates. Environ. Health Perspect. 2003, 111(11):1403-1409.
9. Connelly P.W., Maguire G.F., Picardo C.M., Teiber J.F., Draganov D. Development of an immunoblot assay with infrared fluorescence to quantify paraoxonase 1 in serum and plasma. J. Lipid Res. 2008, 49(1):245-250.
10. Conners C.K., Staff M. Conners[U+05F3] Kiddie Continuous Performance Test (K-CPT): Computer Program for Windows Technical Guide and Software Manual 2001, MHS, Toronto, ON.
11. Costa L.G., Cole T.B., Vitalone A., Furlong C.E. Measurement of paraoxonase (PON1) status as a potential biomarker of susceptibility to organophosphate toxicity. Clin. Chim. Acta 2005, 352(1-2):37-47.
12. Dunn L., Dunn L. Peabody Picture Vocabulary Test, Revised 1981, American Guidance Service, Circle Pines, MN.
13. Dunn L., Padilla E., Lugo D., Dunn L. Test de Vocabulario en Imagenes Peabody: Adaptacion Hispanoamericana (Peabody Picture Vocabulary Test: Hispanic-American Adaptation) 1986, Dunn Educational Services, Inc, Circle Pines, MN.
14. Durak D., Uzun F.G., Kalender S., Ogutcu A., Uzunhisarcikli M., Kalender Y. Malathion-induced oxidative stress in human erythrocytes and the protective effect of vitamins C and E in vitro. Environ. Toxicol. 2009, 24(3):235-242.
15. Engel S.M., Wetmur J., Chen J., Zhu C., Barr D.B., Canfield R.L., et al. Prenatal exposure to organophosphates, paraoxonase 1, and cognitive development in childhood. Environ. Health Perspect. 2011, 119(8):1182-1188.
16. Eskenazi B., Harley K., Bradman A., Weltzien E., Jewell N.P., Barr D.B., et al. Association of in utero organophosphate pesticide exposure and fetal growth and length of gestation in an agricultural population. Environ. Health Perspect. 2004, 112(10):1116-1124.
17. Eskenazi B., Huen K., Marks A., Harley K.G., Bradman A., Barr D.B., et al. PON1 and neurodevelopment in children from the CHAMACOS study exposed to organophosphate pesticides in utero. Environ. Health Perspect. 2010, 118(12):1775-1781.
18. Eskenazi B., Marks A.R., Bradman A., Fenster L., Johnson C., Barr D.B., et al. In utero exposure to dichlorodiphenyltrichloroethane (DDT) and dichlorodiphenyldichloroethylene (DDE) and neurodevelopment among young Mexican American children. Pediatrics 2006, 118(1):233-241.
19. Eskenazi B., Marks A.R., Bradman A., Harley K., Barr D.B., Johnson C., et al. Organophosphate pesticide exposure and neurodevelopment in young Mexican-American children. Environ. Health Perspect. 2007, 115(5):792-798.
20. Franco J.L., Posser T., Mattos J.J., Trevisan R., Brocardo P.S., Rodrigues A.L., et al. Zinc reverses malathion-induced impairment in antioxidant defenses. Toxicol. Lett. 2009, 187(3):137-143.
21. Furlong C.E., Holland N., Richter R.J., Bradman A., Ho A., Eskenazi B. PON1 status of farmworker mothers and children as a predictor of organophosphate sensitivity. Pharmacogenet Genomics 2006, 16(3):183-190.
22. Holland N., Furlong C., Bastaki M., Richter R., Bradman A., Huen K., et al. Paraoxonase polymorphisms, haplotypes, and enzyme activity in latino mothers and newborns. Environ. Health Perspect. 2006, 114(7):985-991.
23. Huen K., Barcellos L., Beckman K., Rose S., Eskenazi B., Holland N. Effects of PON polymorphisms and haplotypes on molecular phenotype in Mexican-American mothers and children. Environ. Mol. Mutagen. 2011, 52(2):105-116.
24. Huen K., Bradman A., Harley K., Yousefi P., Boyd Barr D., Eskenazi B., et al. Organophosphate pesticide levels in blood and urine of women and newborns living in an agricultural community. Environ. Res. 2012, 117:8-16.
25. Huen K., Harley K., Bradman A., Eskenazi B., Holland N. Longitudinal changes in PON1 enzymatic activities in Mexican-American mothers and children with different genotypes and haplotypes. Toxicol. Appl. Pharmacol. 2010, 244(2):181-189.
26. Huen K., Harley K., Brooks J., Hubbard A., Bradman A., Eskenazi B., et al. Developmental changes in PON1 enzyme activity in young children and effects of PON1 polymorphisms. Environ. Health Perspect. 2009, 117(10):1632-1638.
27. Huen K., Richter R., Furlong C., Eskenazi B., Holland N. Validation of PON1 enzyme activity assays for longitudinal studies. Clin. Chim. Acta 2009, 402(1-2):67-74.
28. James R.W. A long and winding road: defining the biological role and clinical importance of paraoxonases. Clin. Chem. Lab. Med. 2006, 44(9):1052-1059.
29. Kujiraoka T., Oka T., Ishihara M., Egashira T., Fujioka T., Saito E., et al. A sandwich enzyme-linked immunosorbent assay for human serum paraoxonase concentration. J. Lipid Res. 2000, 41(8):1358-1363.
30. Li H.L., Liu D.P., Liang C.C. Paraoxonase gene polymorphisms, oxidative stress, and diseases. J. Mol. Med. (Berl.) 2003, 81(12):766-779.
31. Lu C., Barr D.B., Pearson M.A., Waller L.A. Dietary intake and its contribution to longitudinal organophosphorus pesticide exposure in urban/suburban children. Environ. Health Perspect. 2008, 116(4):537-542.
32. Marks A.R., Harley K., Bradman A., Kogut K., Barr D.B., Johnson C., et al. Organophosphate pesticide exposure and attention in young Mexican-American children: the CHAMACOS study. Environ. Health Perspect. 2010, 118(12):1768-1774.
33. McGrath E., Wypij D., Rappaport L.A., Newburger J.W., Bellinger D.C. Prediction of IQ and achievement at age 8 years from neurodevelopmental status at age 1 year in children with D-transposition of the great arteries. Pediatrics 2004, 114(5):e572-e576.
34. McKone T.E., Castorina R., Harnly M.E., Kuwabara Y., Eskenazi B., Bradman A. Merging models and biomonitoring data to characterize sources and pathways of human exposure to organophosphorus pesticides in the Salinas Valley of California. Environ. Sci. Technol. 2007, 41(9):3233-3240.
35. Quirós-Alcalá L., Bradman A., Smith K., Weerasekera G., Odetokun M., Barr D.B., et al. Organophosphorous pesticide breakdown products in house dust and children[U+05F3]s urine. J. Expo. Sci. Environ. Epidemiol. 2012, 22(6):559-568.
36. Radloff L. The CES-D scale: a self-report depression scale for research in the general population. Appl. Psychol. Meas. 1977, 1(3):385-401.
37. Richter R.J., Furlong C.E. Determination of paraoxonase (PON1) status requires more than genotyping. Pharmacogenetics 1999, 9(6):745-753.
38. Rojas-Garcia A.E., Solis-Heredia M.J., Pina-Guzman B., Vega L., Lopez-Carrillo L., Quintanilla-Vega B. Genetic polymorphisms and activity of PON1 in a Mexican population. Toxicol. Appl. Pharmacol. 2005, 205(3):282-289.
39. Stata Corporation Stata Statistical Software: Release 2009, 11. Stata Corp LP, College Station, TX.
40. Sugland B.W., Zaslow M., Smith J.R., Brooks-Gunn J., Coates D., Blumenthal C., et al. The early childhood home inventory and home-short form in differing racial/ethnic groups. J. Fam. Issues 1995, 16(5):632-663.
41. Wechsler D. Wechsler Intelligence Scale for Children-Fourth Edition (WISC-IV) Administration and Scoring Manual 2003, Harcourt Assessment Incorporated, San Antonio, TX.
42. Weldon R.H. Biomonitoring Persistent and Non-persistent Chemicals in Human Breast Milk and Endocrine Disruption of Lactation 2010, University of California, Berkeley, Berkeley.
43. Wessels D., Barr D.B., Mendola P. Use of biomarkers to indicate exposure of children to organophosphate pesticides: implications for a longitudinal study of children[U+05F3]s environmental health. Environ. Health Perspect. 2003, 111(16):1939-1946.
44. Whyatt R.M., Barr D.B., Camann D.E., Kinney P.L., Barr J.R., Andrews H.F., et al. Contemporary-use pesticides in personal air samples during pregnancy and blood samples at delivery among urban minority mothers and newborns. Environ. Health Perspect. 2003, 111(5):749-756.
45. Williams M.K., Rundle A., Holmes D., Reyes M., Hoepner L.A., Barr D.B., et al. Changes in pest infestation levels, self-reported pesticide use, and permethrin exposure during pregnancy after the 2000-2001 U.S. Environmental Protection Agency restriction of organophosphates. Environ. Health Perspect. 2008, 116(12):1681-1688.
46. Wolff M.S., Engel S., Berkowitz G., Teitelbaum S., Siskind J., Barr D.B., et al. Prenatal pesticide and PCB exposures and birth outcomes. Pediatr. Res. 2007, 61(2):243-250.
47. Zartarian V.G., Ozkaynak H., Burke J.M., Zufall M.J., Rigas M.L., Furtaw E.J. A modeling framework for estimating children's residential exposure and dose to chlorpyrifos via dermal residue contact and nondietary ingestion. Environ. Health Perspect. 2000, 108(6):505-514.