Exercise training and artery function in humans: Nonresponse and its relationship to cardiovascular risk factors

Journal of Applied Physiology

Volumn 117, Issue 4, 2014, Pages 345-352

  Green, Daniel J ^a,b   Eijsvogels, Thijs ^c,d   Bouts, Yvette M ^a,c   Maiorana, Andrew J ^e,f   Naylor, Louise H ^a   Scholten, Ralph R ^c   Spaanderman, Marc E A ^c   Pugh, Christopher J A ^b   Sprung, Victoria S ^b   Schreuder, Tim ^c   Jones, Helen ^b   Cable, Tim ^b   Hopman, Maria T E ^c   Thijssen, Dick H J ^b,c  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^d HARTFORD HOSPITAL   (United States)

^e CURTIN UNIVERSITY   (Australia)

^f ROYAL PERTH HOSPITAL   (Australia)

Author keywords

Cardiovascular risk; Endothelial function; Flow mediated dilation; Nitric oxide; Physical activity

Indexed keywords

CHOLESTEROL; VASODILATOR AGENT;

ADULT; AGED; ARTERIAL PRESSURE; ARTERY; BLOOD; BODY MASS; CARDIOVASCULAR DISEASE; DIAGNOSTIC USE; ECHOGRAPHY; ENDURANCE; EXERCISE; FEMALE; FITNESS; HUMAN; MALE; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSICAL EDUCATION; PHYSIOLOGY; RISK FACTOR; VASODILATATION;

ADULT; AGED; ARTERIAL PRESSURE; ARTERIES; BODY MASS INDEX; CARDIOVASCULAR DISEASES; CHOLESTEROL; EXERCISE; FEMALE; HUMANS; MALE; MIDDLE AGED; PHYSICAL EDUCATION AND TRAINING; PHYSICAL ENDURANCE; PHYSICAL FITNESS; RISK FACTORS; VASODILATION; VASODILATOR AGENTS;

EID: 84907347239     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00354.2014     Document Type: Article

References (38)

1. Atkinson G, Batterham AM, Thijssen DH, Green DJ. A new approach to improve the specificity of flow-mediated dilation for indicating endothelial function in cardiovascular research. J Hypertens 31: 287-291, 2013.
2. Birk GK, Dawson EA, Atkinson C, Haynes A, Cable NT, Thijssen DH, Green DJ. Brachial artery adaptation to lower limb exercise training: role of shear stress. J Appl Physiol 112: 1653-1658, 2012.
3. Black MA, Cable NT, Thijssen DH, Green DJ. Importance of measuring the time course of flow-mediated dilatation in humans. Hypertension 51: 203-210, 2008.
4. Bouchard C, Blair SN, Church TS, Earnest CP, Hagberg JM, Hakkinen K, Jenkins NT, Karavirta L, Kraus WE, Leon AS, Rao DC, Sarzynski MA, Skinner JS, Slentz CA, Rankinen T. Adverse metabolic response to regular exercise: is it a rare or common occurrence? PLoS One 7: e37887, 2012.
5. Bouchard C, Rankinen T. Individual differences in response to regular physical activity. Med Sci Sports Exerc 33: S446-S451; discussion S452-S443, 2001.
6. Bouchard C, Sarzynski MA, Rice TK, Kraus WE, Church TS, Sung YJ, Rao DC, Rankinen T. Genomic predictors of the maximal O2 uptake response to standardized exercise training programs. J Appl Physiol 110: 1160-1170, 2011.
7. Cornelissen VA, Buys R, Smart NA. Endurance exercise beneficially affects ambulatory blood pressure: a systematic review and meta-analysis. J Hypertens 31: 639-648, 2013.
8. Cornelissen VA, Fagard RH, Coeckelberghs E, Vanhees L. Impact of resistance training on blood pressure and other cardiovascular risk factors: a meta-analysis of randomized, controlled trials. Hypertension 58: 950-958, 2011.
9. Dawson EA, Rathore S, Cable NT, Wright DJ, Morris JL, Green DJ. Impact of catheter insertion using the radial approach on vasodilatation in humans. Clin Sci (Lond) 118: 633-640, 2010.
10. Green DJ, Dawson EA, Groenewoud HM, Jones H, Thijssen DH. Is flow-mediated dilation nitric oxide mediated?: A meta-analysis. Hypertension 63: 376-382, 2014.
11. Green DJ, Jones H, Thijssen D, Cable NT, Atkinson G. Flow-mediated dilation and cardiovascular event prediction: does nitric oxide matter? Hypertension 57: 363-369, 2011.
12. Green DJ, O'Driscoll G, Joyner MJ, Cable NT. Exercise and cardiovascular risk reduction: time to update the rationale for exercise? J Appl Physiol 105: 766-768, 2008.
13. Green DJ, Walsh JH, Maiorana A, Best MJ, Taylor RR, O'Driscoll JG. Exercise-induced improvement in endothelial dysfunction is not mediated by changes in CV risk factors: pooled analysis of diverse patient populations. Am J Physiol Heart Circ Physiol 285: H2679-H2687, 2003.
14. Hunt JE, Galea D, Tufft G, Bunce D, Ferguson RA. Time course of regional vascular adaptations to low load resistance training with blood flow restriction. J Appl Physiol 115: 403-411, 2013.
15. Inaba Y, Chen JA, Bergmann SR. Prediction of future cardiovascular outcomes by flow-mediated vasodilatation of brachial artery: a metaanalysis. Int J Cardiovasc Imaging 26: 631-640, 2010.
16. Jones H, Green DJ, George K, Atkinson G. Intermittent exercise abolishes the diurnal variation in endothelial-dependent flow-mediated dilation in humans. Am J Physiol Regul Integr Comp Physiol 298: R427-R432, 2010.
17. Joyner MJ, Green DJ. Exercise protects the cardiovascular system: effects beyond traditional risk factors. J Physiol 587: 5551-5558, 2009.
18. Kodama S, Tanaka S, Saito K, Shu M, Sone Y, Onitake F, Suzuki E, Shimano H, Yamamoto S, Kondo K, Ohashi Y, Yamada N, Sone H. Effect of aerobic exercise training on serum levels of high-density lipoprotein cholesterol: a meta-analysis. Arch Intern Med 167: 999-1008, 2007.
19. Laughlin MH. Endothelium-mediated control of coronary vascular tone after chronic exercise training. Med Sci Sports Exerc 27: 1135-1144, 1995.
20. Lee IM, Sesso HD, Oguma Y, Paffenbarger RS Jr. Relative intensity of physical activity and risk of coronary heart disease. Circulation 107: 1110-1116, 2003.
21. Lee IM, Shiroma EJ, Lobelo F, Puska P, Blair SN, Katzmarzyk PT. Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy. Lancet 380: 219-229, 2012.
22. Maiorana AJ, Naylor LH, Exterkate A, Swart A, Thijssen DH, Lam K, O'Driscoll G, Green DJ. The impact of exercise training on conduit artery wall thickness and remodeling in chronic heart failure patients. Hypertension 57: 56-62, 2011.
23. Midgley AW, McNaughton LR, Polman R, Marchant D. Criteria for determination of maximal oxygen uptake: a brief critique and recommendations for future research. Sports Med 37: 1019-1028, 2007.
24. Mora S, Cook N, Buring JE, Ridker PM, Lee IM. Physical activity and reduced risk of cardiovascular events: potential mediating mechanisms. Circulation 116: 2110-2118, 2007.
25. Morris JN, Heady JA, Raffle PA, Roberts CG, Parks JW. Coronary heart-disease and physical activity of work. Lancet 265: 1111-1120; concl, 1953.
26. Ras RT, Streppel MT, Draijer R, Zock PL. Flow-mediated dilation and cardiovascular risk prediction: A systematic review with meta-analysis. Int J Cardiol 168: 344-351, 2013.
27. Rowley NJ, Dawson EA, Birk GK, Cable NT, George K, Whyte G, Thijssen DH, Green DJ. Exercise and arterial adaptation in humans: uncoupling localized and systemic effects. J Appl Physiol 110: 1190-1195, 2011.
28. Skinner JS, Jaskolski A, Jaskolska A, Krasnoff J, Gagnon J, Leon AS, Rao DC, Wilmore JH, Bouchard C. Age, sex, race, initial fitness, and response to training: the HERITAGE Family Study. J Appl Physiol 90: 1770-1776, 2001.
29. Spence AL, Naylor LH, Carter HH, Buck CL, Dembo L, Murray CP, Watson P, Oxborough D, George KP, Green DJ. A prospective randomised longitudinal MRI study of left ventricular adaptation to endurance and resistance exercise training in humans. J Physiol 589: 5443-5452, 2011.
30. Takase B, Uehata A, Akima T, Nagai T, Nishioka T, Hamabe A, Satomura K, Ohsuzu F, Kurita A. Endothelium-dependent flow-mediated vasodilation in coronary and brachial arteries in suspected coronary artery disease. Am J Cardiol 82: 1535-1539, A1537-A1538, 1998.
31. Thijssen DH, Black MA, Pyke KE, Padilla J, Atkinson G, Harris RA, Parker B, Widlansky ME, Tschakovsky ME, Green DJ. Assessment of flow-mediated dilation in humans: a methodological and physiological guideline. Am J Physiol Heart Circ Physiol 300: H2-H12, 2011.
32. Thompson PD, Lim V. Physical activity in the prevention of atherosclerotic coronary heart disease. Curr Treat Options Cardiovasc Med 5: 279-285, 2003.
33. Tinken TM, Thijssen DH, Black MA, Cable NT, Green DJ. Time course of change in vasodilator function and capacity in response to exercise training in humans. J Physiol 586: 5003-5012, 2008.
34. Tinken TM, Thijssen DH, Hopkins N, Dawson EA, Cable NT, Green DJ. Shear stress mediates endothelial adaptations to exercise training in humans. Hypertension 55: 312-318, 2010.
35. Weinheimer EM, Sands LP, Campbell WW. A systematic review of the separate and combined effects of energy restriction and exercise on fat-free mass in middle-aged and older adults: implications for sarcopenic obesity. Nutr Rev 68: 375-388, 2010.
36. Williams MR, Westerman RA, Kingwell BA, Paige J, Blombery PA, Sudhir K, Komesaroff PA. Variations in endothelial function and arterialv compliance during the menstrual cycle. J Clin Endocrinol Metab 86: 5389-5395, 2001.
37. Wisloff U, Stoylen A, Loennechen JP, Bruvold M, Rognmo O, Haram PM, Tjonna AE, Helgerud J, Slordahl SA, Lee SJ, Videm V, Bye A, Smith GL, Najjar SM, Ellingsen O, Skjaerpe T. Superior cardiovascular effect of aerobic interval training versus moderate continuous training in heart failure patients: a randomized study. Circulation 115: 3086-3094, 2007.
38. Woodman RJ, Playford DA, Watts GF, Cheetham C, Reed C, Taylor RR, Puddey IB, Beilin LJ, Burke V, Mori TA, Green D. Improved analysis of brachial artery ultrasound using a novel edge-detection software system. J Appl Physiol 91: 929-937, 2001.